Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: A Roadmap to the Clinical Use of EVs
Discussion Leader: Dandan Zhu (Exopharm, Australia)
3:45 pm - 4:20 pm
Susmita Sahoo (Icahn School of Medicine at Mount Sinai, United States)
"Therapeutic and Diagnostic EVs in Cardiovascular Disease: A Roadmap to Clinic"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Biological Characteristics and Heterogeneity of EVs
Discussion Leader: Mitja Heinemann (Leipzig University Hospital, Germany)
7:30 pm - 7:50 pm
Dylan Krajewski (University of Connecticut Health Center, United States)
"Polarized Release of Endothelial-derived EVs: Significance for EV:Leukocyte Interactions"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
David Rufino-Ramos (Center for Neuroscience and Cell Biology of University of Coimbra, Portugal, Portugal)
"Extracellular Communication in the Brain through Functional Transfer of CRE ExRNA"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Janet Sorrells (University of Illinois at Urbana-Champaign, United States)
"Characterization of Metabolic Signatures of Extracellular Vesicles in Breast Cancer Using Label-Free Nonlinear Optical Microscopy"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Colin Hisey (The Ohio State University, United States)
"Autoencoder-enabled Quantitative Detection of Extracellular Vesicle Mixtures Using Nanoplasmonic Sensors"
9:20 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Elucidating the Adverse Potential of EVs in Disease Initiation and Propagation
Discussion Leader: Nina Erwin (University of Florida, United States)
9:00 am - 9:20 am
Camille Trinidad (University of Kansas Medical Center, United States)
"Extracellular Vesicle Proteomic Fingerprinting of Serous Ovarian Cancer and Fallopian Tube Cell Lines and Tissues to Identify Novel Biomarkers for Early Detection"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Jeff Bouffard (Concordia University, Canada)
"Saccharomyces cerevisiae Transfers Thermotolerance Between Cells Using Extracellular Vesicles Loaded With Heat Shock Proteins"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Kaitlyn Whitefoot-Keliin (Central Michigan University, United States)
"Neutrophil-derived EVs Associate With DNA Released During NETosis"
10:20 am - 10:30 am
Discussion
10:30 am - 10:50 am
Madhusudhan Reddy Bobbili (Ludwig Boltzmann Institute for Traumatology, Austria)
"A Ganglioside-binding IgM as a Diagnostic Tool: Ganglioside-enriched Large Oncosomes are Sufficient for Cancer Prediction"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Therapeutic Potential of EVs in Disease Treatment
Discussion Leader: Vidyanand (Anand) Sasidharan (Stowers, United States)
1:30 pm - 1:40 pm
Ana Salazar Puerta (The Ohio State University, United States)
"Designer Extracellular Vesicle Therapies for Acute Respiratory Distress Syndrome"
1:40 pm - 1:45 pm
Discussion
1:45 pm - 1:55 pm
Zachary Greenberg (University of Florida, United States)
"An End-to-End Machine Learned Peptide Aptamer Strategy to Develop Translational Precision Extracellular Vesicle Therapeutics"
1:55 pm - 2:00 pm
Discussion
2:00 pm - 2:10 pm
Daniel Levy (University of Maryland - College Park, United States)
"Investigating the Therapeutic Potential of Induced Pluripotent Stem Cell-derived Extracellular Vesicles"
2:10 pm - 2:15 pm
Discussion
2:15 pm - 2:25 pm
Koushik Debnath (University of Illinois at Chicago, United States)
"Investigating the Role of Extracellular Vesicle Subpopulations in Restoration of Vascular Hyperpermeability"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes
