Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Starting Early Embryogenesis
7:40 pm - 7:50 pm
Opening Remarks
7:50 pm - 8:00 pm
Introduction by Discussion Leader
8:00 pm - 8:20 pm
"Developmentally Programmed Tankyrase Activity Licenses Progression of Embryonic Genome Activation"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Imaging How Cells Choose Their Fate, Shape and Position in the Living Embryo"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"The Embryonic Origins of Pluripotency"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Stem Cell Maintenance, piRNAs and Monospermic Fertilization"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Gamete Fusion Mechanisms"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"The Molecular Underpinnings of the C. elegans Fertilization Synapse"
11:15 am - 11:25 am
Discussion
11:25 am - 11:50 am
"Species-Specificity of Fertilization"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"TMEM95 Is Required for Sperm-Egg Membrane Fusion"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Signaling During Gamete Maturation and Fertilization
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"CatSper Regulation by PKA and the Importance of Acrosomal pH for the Acrosome Reaction"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"Dissecting Non-Genomic Progesterone-Dependent Signaling Pathways that Induce Frog Oocyte Maturation"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"The Plasma Membrane Compartmentalization of Na/K ATPase During Sperm Activation Modulates Sperm Migration and Fertility in the Nematode C. elegans "
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"A Chloride Channel Provides the First Defense Against Abnormal Fertilization in Xenopus laevis "
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
The Evolution of Reproductive Strategies and Sperm Competition
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"The Evolutionary Significance of Post-Testicular Sperm Maturation: Insights from Birds, Reptiles and Mammals"
9:30 am - 9:40 am
Discussion
9:40 am - 10:00 am
"How Variations in X Chromosome Segregation Support Skewed Sex Ratios in the Nematode Auanema rhodensis "
10:00 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 11:00 am
"Ejaculate Composition: The Roles of Rivals and Ageing"
11:00 am - 11:10 am
Discussion
11:10 am - 11:30 am
"Egg Activation Mechanisms in Drosophila : Uncovering 'Deep Homology'"
11:30 am - 11:40 am
Discussion
11:40 am - 11:45 am
Introduction by Discussion Leader
11:45 am - 11:55 am
"Metalloproteinase Activity Is Required for Release of Oocyte-Zonapellucida Adhesion"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Insights into Reproductive and Intellectual Disorders in Quiescent Oocytes"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Imaging the Structural Organization of Mammalian Spermatozoa from the Cellular to the Supramolecular Level"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
The Role of the Reproductive Tract During Gametogenesis and Fertilization
7:30 pm - 7:50 pm
"Characterizing Chromatin and Transcriptional States of Germ Cells"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Intrinsic and Extrinsic Forces Are Major Drivers of Wolffian Duct Morphogenesis"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Extracellular Vesicles in the Female Tract: Interaction of Exosomes with Sperm"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"A Changing Matrix: Ovarian Hyaluronan, Inflammation and Reproductive Aging"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Meiosis During Sperm and Egg Development
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Crossover Control During Meiosis"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"How Meiosis Ensures Accurate Chromosome Segregation into Sperm"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"Oocyte Meiotic Progression in the Jellyfish Model Clytia hemisphaerica "
11:15 am - 11:25 am
Discussion
11:25 am - 11:45 am
"PATL Is Required for Oocyte Meiosis/Maturation and Early Development"
11:45 am - 11:55 am
Discussion
11:55 am - 12:20 pm
"Niche Cells Spatially Restrict Stem-Cell Self-Renewal Signalling via Receptor-Ligand Degradation"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Sperm Motility and Finding the Egg
7:30 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:10 pm
"Cryo-Electron Microscopy Studies Provide New Insights into the Structure and Motility of Sperm Flagella"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
"Sperm Ca2+ Signaling Nanodomains in Motility Regulation: CatSper Channels and Beyond"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"New Insights into Molecular Pathways Leading to Human Sperm Capacitation"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Selected Poster Presentations
Short talks selected from the posters.
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:20 am
"Characterization of Candidate Fusexin-Like Gamete Fusion Proteins on Mammalian Eggs"
9:20 am - 9:25 am
Discussion
9:25 am - 9:35 am
"Self-Organized Nuclear Positioning Synchronizes the Cell Cycle in Drosophila Embryos"
9:35 am - 9:40 am
Discussion
9:40 am - 9:50 am
"Change in Energy Metabolism During Sperm Capacitation in Mouse Strains with Different Fecundity"
9:50 am - 9:55 am
Discussion
9:55 am - 10:05 am
"Novel SLO3 Inhibitors as Blockers of Human Sperm Capacitation"
10:05 am - 10:10 am
Discussion
10:10 am - 10:45 am
Coffee Break
10:45 am - 10:50 am
Introduction by Discussion Leader
10:50 am - 11:00 am
"Intercellular Communication Between the Luteinizing Hormone Receptor and the NPR2 Guanylyl Cyclase in Mouse Ovarian Follicles"
11:00 am - 11:05 am
Discussion
11:05 am - 11:15 am
"Egg Activation in Drosophila "
11:15 am - 11:20 am
Discussion
11:20 am - 11:30 am
"Indirect Sexual Selection Drives Rapid Evolution of an Intrinsically Disordered Sperm Protein"
11:30 am - 11:35 am
Discussion
11:35 am - 11:40 am
Introduction by Discussion Leader
11:40 am - 12:20 pm
"Historical Perspectives: Human Preimplantation Embryos, 1969-2019"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Assisted Reproductive Technologies: New Approaches and Ethical Concerns
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Bringing Andrology into the 21st Century: High Throughput Screening for Motile Human Sperm"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"ART in the Era of Single Cell Genomics"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
"The Myth of the Designer Child: Parental Decision Making in an Era of Expanding Reproductive Options"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
Closing Remarks
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure