Sunday 
 
 
2:00 pm - 9:00 pm 
	
Arrival and Check-in
 
 
						 
						 
					
						
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						 
						 
					
						
						
7:30 pm - 7:40 pm 
	
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
 
 
						 
						 
					
						
						
7:40 pm - 9:30 pm 
	
Evolution of Gametes and Fertilization Mechanisms 
 
 
 
						 
						 
					
						
						
7:40 pm - 7:45 pm 
	
Introduction by Discussion Leader
 
 
						 
						 
					
						
						
7:45 pm - 8:10 pm 
	
"Sperm Development in Drosophila" 
 
 
 
						 
						 
					
						
						
8:10 pm - 8:20 pm 
	
Discussion
 
 
						 
						 
					
						
						
8:20 pm - 8:45 pm 
	
"Egg Size Plasticity in the Reproductively Specialized Queens of Honey Bees" 
 
 
 
						 
						 
					
						
						
8:45 pm - 8:55 pm 
	
Discussion
 
 
						 
						 
					
						
						
8:55 pm - 9:20 pm 
	
"Ancient Molecular Origins of Fertilization Failure" 
 
 
 
						 
						 
					
						
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						 
						 
					
						
						
	Monday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						 
						 
					
						
						
8:30 am - 9:00 am 
	
Group Photo
 
 
						 
						 
					
						
						
9:00 am - 12:30 pm 
	
Sperm Maturation, Function, and Guidance 
 
 
 
						 
						 
					
						
						
9:00 am - 9:10 am 
	
Introduction by Discussion Leader
 
 
						 
						 
					
						
						
9:10 am - 9:35 am 
	
"Sperm Specific Cytoskeletal Proteins; Elaborating on Their Role in Spermatogenesis Using Gene Edited Mice" 
 
 
 
						 
						 
					
						
						
9:35 am - 9:45 am 
	
Discussion
 
 
						 
						 
					
						
						
9:45 am - 10:10 am 
	
"A (male) Na+ /H+  Exchanger with Potential" 
 
 
 
						 
						 
					
						
						
10:10 am - 10:20 am 
	
Discussion
 
 
						 
						 
					
						
						
10:20 am - 10:50 am 
	
Coffee Break
 
 
						 
						 
					
						
						
10:50 am - 11:15 am 
	
"Mammalian CatSper: A Fresh Perspective on an Essential Channel" 
 
 
 
						 
						 
					
						
						
11:15 am - 11:25 am 
	
Discussion
 
 
						 
						 
					
						
						
11:25 am - 11:50 am 
	
"Protecting Paternal Chromosomes from Premature Division in the Drosophila Egg" 
 
 
 
						 
						 
					
						
						
11:50 am - 12:00 pm 
	
Discussion
 
 
						 
						 
					
						
						
12:00 pm - 12:10 pm 
	
"TEX38/ZDHHC19 Complex Regulates Sperm Head Morphogenesis and is Essential for Male Fertility in Mice" 
 
 
 
						 
						 
					
						
						
12:10 pm - 12:15 pm 
	
Discussion
 
 
						 
						 
					
						
						
12:15 pm - 12:25 pm 
	
"Sperm Metabolism Beyond Glucose" 
 
 
 
						 
						 
					
						
						
12:25 pm - 12:30 pm 
	
Discussion
 
 
						 
						 
					
						
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						 
						 
					
						
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						 
						 
					
						
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						 
						 
					
						
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						 
						 
					
						
						
7:30 pm - 9:30 pm 
	
Oogenesis and Preparation for Fertilization 
 
 
 
						 
						 
					
						
						
7:30 pm - 7:45 pm 
	
Introduction by Discussion Leader
 
 
						 
						 
					
						
						
7:45 pm - 8:10 pm 
	
"Meiotic Midbodies: Large Extracellular Vesicles That Contribute to Embryonic Development" 
 
 
 
						 
						 
					
						
						
8:10 pm - 8:20 pm 
	
Discussion
 
 
						 
						 
					
						
						
8:20 pm - 8:45 pm 
	
"Mechanics of Oocyte Divisions and Impact on Competence" 
 
 
 
						 
						 
					
						
						
8:45 pm - 8:55 pm 
	
Discussion
 
 
						 
						 
					
						
						
8:55 pm - 9:20 pm 
	
"Imaging Approaches to Understand the Events During the Oocyte-to-Embryo Transition" 
 
 
 
						 
						 
					
						
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						 
						 
					
						
						
	Tuesday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						 
						 
					
						
						
9:00 am - 12:30 pm 
	
The Influence of the Reproductive Tract and the Environment on Fertilization 
 
 
 
						 
						 
					
						
						
9:00 am - 9:10 am 
	
Introduction by Discussion Leader
 
 
						 
						 
					
						
						
9:10 am - 9:35 am 
	
"Contribution of the Epididymis to Early Embryo Development" 
 
 
 
						 
						 
					
						
						
9:35 am - 9:45 am 
	
Discussion
 
 
						 
						 
					
						
						
9:45 am - 10:10 am 
	
"Saving Eggs: The Cumulative Impact of Ovulation on Fertility and Reproductive Lifespan" 
 
 
 
						 
						 
					
						
						
10:10 am - 10:20 am 
	
Discussion
 
 
						 
						 
					
						
						
10:20 am - 10:50 am 
	
Coffee Break
 
 
						 
						 
					
						
						
10:50 am - 11:15 am 
	
"Oviductin: A Key Regulator of Species-Specific Mammalian Fertilization" 
 
 
 
						 
						 
					
						
						
11:15 am - 11:25 am 
	
Discussion
 
 
						 
						 
					
						
						
11:25 am - 11:50 am 
	
"Cytoplasmic Mechanics, Aging and Rejuvenation of Mammalian Oocytes" 
 
 
 
						 
						 
					
						
						
11:50 am - 12:00 pm 
	
Discussion
 
 
						 
						 
					
						
						
12:00 pm - 12:10 pm 
	
"In situ Sperm Entry into the Oocyte During Mouse Fertilization by Nanometer Resolution FIB-SEM Analysis" 
 
 
 
						 
						 
					
						
						
12:10 pm - 12:15 pm 
	
Discussion
 
 
						 
						 
					
						
						
12:15 pm - 12:25 pm 
	
"Bacterial Vaginosis Toxins Impair Sperm Capacitation and Fertilization" 
 
 
 
						 
						 
					
						
						
12:25 pm - 12:30 pm 
	
Discussion
 
 
						 
						 
					
						
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						 
						 
					
						
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						 
						 
					
						
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						 
						 
					
						
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						 
						 
					
						
						
7:30 pm - 9:30 pm 
	
The Molecular Basis of Sperm-Egg Interaction 
 
 
 
						 
						 
					
						
						
7:30 pm - 7:45 pm 
	
Introduction by Discussion Leader
 
 
						 
						 
					
						
						
7:45 pm - 8:10 pm 
	
"Components and Assembly of the C. Elegans  Fertilization Synapse" 
 
 
 
						 
						 
					
						
						
8:10 pm - 8:20 pm 
	
Discussion
 
 
						 
						 
					
						
						
8:20 pm - 8:45 pm 
	
"Molecular Players Involved in Double Fertilization of Flowering Plants" 
 
 
 
						 
						 
					
						
						
8:45 pm - 8:55 pm 
	
Discussion
 
 
						 
						 
					
						
						
8:55 pm - 9:20 pm 
	
"The Key to Life: Unlocking the Molecular Mechanisms of Vertebrate Fertilization" 
 
 
 
						 
						 
					
						
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						 
						 
					
						
						
	Wednesday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						 
						 
					
						
						
9:00 am - 12:30 pm 
	
The Events of Egg Activation and Initiation of Development 
 
 
 
						 
						 
					
						
						
9:00 am - 9:10 am 
	
Introduction by Discussion Leader
 
 
						 
						 
					
						
						
9:10 am - 9:35 am 
	
"Double Fertilization and Activation of Seed Development in Plants" 
 
 
 
						 
						 
					
						
						
9:35 am - 9:45 am 
	
Discussion
 
 
						 
						 
					
						
						
9:45 am - 10:10 am 
	
"Mechanisms Controlling Transcriptional Silencing and Chromatin Dynamics Underlying Oocyte Developmental Competence" 
 
 
 
						 
						 
					
						
						
10:10 am - 10:20 am 
	
Discussion
 
 
						 
						 
					
						
						
10:20 am - 10:50 am 
	
Coffee Break
 
 
						 
						 
					
						
						
10:50 am - 11:15 am 
	
"Trafficking of RNAs and Organelles Regulating Preimplantation Embryogenesis" 
 
 
 
						 
						 
					
						
						
11:15 am - 11:25 am 
	
Discussion
 
 
						 
						 
					
						
						
11:25 am - 11:50 am 
	
"Mechanics of Blastocyst Morphogenesis" 
 
 
 
						 
						 
					
						
						
11:50 am - 12:00 pm 
	
Discussion
 
 
						 
						 
					
						
						
12:00 pm - 12:10 pm 
	
"F-Actin Regulates Polar MTOC Organization and the Fidelity of Meiotic Spindle Formation" 
 
 
 
						 
						 
					
						
						
12:10 pm - 12:15 pm 
	
Discussion
 
 
						 
						 
					
						
						
12:15 pm - 12:25 pm 
	
"Regulation of Maternal Phospho-Proteins During Oocyte Maturation and Egg Activation in Flies and Mice" 
 
 
 
						 
						 
					
						
						
12:25 pm - 12:30 pm 
	
Discussion
 
 
						 
						 
					
						
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						 
						 
					
						
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						 
						 
					
						
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						 
						 
					
						
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						 
						 
					
						
						
7:30 pm - 9:30 pm 
	
The Science of Contraception 
 
 
 
						 
						 
					
						
						
7:30 pm - 7:40 pm 
	
Introduction by Discussion Leader
 
 
						 
						 
					
						
						
7:40 pm - 8:05 pm 
	
"Genetic Validation and Chemical Inhibition of Contraceptive Targets" 
 
 
 
						 
						 
					
						
						
8:05 pm - 8:15 pm 
	
Discussion
 
 
						 
						 
					
						
						
8:15 pm - 8:40 pm 
	
"Antisperm Antibodies Targeting the Egg–Sperm Fertilization Complex" 
 
 
 
						 
						 
					
						
						
8:40 pm - 8:50 pm 
	
Discussion
 
 
						 
						 
					
						
						
8:50 pm - 9:10 pm 
	
"A Humanized C. elegans Model Facilitated the Discovery of Potential Male Birth Control Pharmaceuticals" 
 
 
 
						 
						 
					
						
						
9:10 pm - 9:15 pm 
	
Discussion
 
 
						 
						 
					
						
						
9:15 pm - 9:25 pm 
	
"STED Microscopy Reveals a Highly Structured Distribution of Na+,K+-ATPase a4 and a1 Isoforms in Sperm" 
 
 
 
						 
						 
					
						
						
9:25 pm - 9:30 pm 
	
Discussion
 
 
						 
						 
					
						
						
	Thursday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						 
						 
					
						
						
8:30 am - 9:00 am 
	
Business Meeting 
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s) 
 
 
						 
						 
					
						
						
9:00 am - 12:30 pm 
	
Technologies for Understanding and Improving Reproduction 
 
 
 
						 
						 
					
						
						
9:00 am - 9:10 am 
	
Introduction by Discussion Leader
 
 
						 
						 
					
						
						
9:10 am - 9:35 am 
	
"Microfluidics and Machine Learning for Understanding Reproduction" 
 
 
 
						 
						 
					
						
						
9:35 am - 9:45 am 
	
Discussion
 
 
						 
						 
					
						
						
9:45 am - 10:10 am 
	
"High-Resolution Cryo-EM Structures of Sperm Axonemes Across Diverse Species" 
 
 
 
						 
						 
					
						
						
10:10 am - 10:20 am 
	
Discussion
 
 
						 
						 
					
						
						
10:20 am - 10:50 am 
	
Coffee Break
 
 
						 
						 
					
						
						
10:50 am - 11:15 am 
	
"mRNA-Based Therapy: A New Approach to Restore Sperm Motility and Fertility in a Mouse Model of Male Infertility" 
 
 
 
						 
						 
					
						
						
11:15 am - 11:25 am 
	
Discussion
 
 
						 
						 
					
						
						
11:25 am - 11:50 am 
	
"Construction of Gene Regulatory Networks in Oocytes" 
 
 
 
						 
						 
					
						
						
11:50 am - 12:00 pm 
	
Discussion
 
 
						 
						 
					
						
						
12:00 pm - 12:10 pm 
	
"Assessing Human Sperm Fertilization Potential with a JUNO-Based Binding Assay: Insights from Vitrified Samples" 
 
 
 
						 
						 
					
						
						
12:10 pm - 12:15 pm 
	
Discussion
 
 
						 
						 
					
						
						
12:15 pm - 12:25 pm 
	
"The Structure of Giant Proteasomes Islands in the Human Sperm Nucleus" 
 
 
 
						 
						 
					
						
						
12:25 pm - 12:30 pm 
	
Discussion
 
 
						 
						 
					
						
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						 
						 
					
						
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						 
						 
					
						
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						 
						 
					
						
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						 
						 
					
						
						
7:30 pm - 9:30 pm 
	
Keynote Session: Learning Reproduction and Development from Synthetic Embryology and Embryoid Models 
 
 
 
						 
						 
					
						
						
7:30 pm - 7:45 pm 
	
Introduction by Discussion Leader
 
 
						 
						 
					
						
						
7:45 pm - 7:55 pm 
	
"Probing the Structural Motifs of Proteins That Polymerize the Vitelline Layer of the C. Elegans Egg Coat" 
 
 
 
						 
						 
					
						
						
7:55 pm - 8:00 pm 
	
Discussion
 
 
						 
						 
					
						
						
8:00 pm - 8:10 pm 
	
"Metabolic Regulation of Epigenetic Reprogramming at Fertilization" 
 
 
 
						 
						 
					
						
						
8:10 pm - 8:15 pm 
	
Discussion
 
 
						 
						 
					
						
						
8:15 pm - 9:15 pm 
	
"Synthetic Ex Utero Embryogenesis: From Naive Stem Cells to Bona Fide Whole Embryo Models" 
 
 
 
						 
						 
					
						
						
9:15 pm - 9:30 pm 
	
Discussion
 
 
						 
						 
					
						
						
	Friday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						 
						 
					
						
						
9:00 am 
	
Departure