| SUNDAY | 
| 4:00 pm - 8:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:45 pm) | 
| 6:00 pm | Dinner | 
| 7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff | 
| 7:40 pm - 9:30 pm | Keynote presentations: The FGF family | 
|  | Discussion Leaders: Sabine Werner (ETH Zurich, Switzerland) and Moosa Mohammadi (New York University School of Medicine, New York, USA) | 
| 7:40 pm - 8.00 pm | Judith Abraham (Novartis Institutes for BioMedical Research, Emeryville, USA) "Key events of the 'early days' of FGF research"
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| 8:00 pm - 8:10 pm | Discussion | 
| 8:10 pm - 8:35 pm | Joseph Schlessinger (Yale University, New Haven, USA) "Regulatory mechanisms underlying FGF receptors and other receptor tyrosine kinases"
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| 8:35 pm - 8:45 pm | Discussion | 
| 8:45 pm - 9:10 pm | Steven Kliewer (University of Texas, Dallas, USA) "Endocrine FGFs: From feast to famine"
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| 9:10 pm - 9:20 pm | Discussion | 
| MONDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 8:30 am | Group Photo | 
| 9:00 am - 12:30 pm | Biochemistry of FGFs, FGF signaling | 
|  | Discussion Leader: Jeremy Turnbull (University of Liverpool, UK) | 
| 9:00 am - 9:20 am | Jeremy Turnbull (University of Liverpool, UK) "Extracellular regulation of FGF signalling - Roles of anosmin and heparan sulfates"
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| 9:20 am - 9:30 am | Discussion | 
| 9:30 am - 9:50 am | David Fernig (University of Liverpool, UK) "Tracking of individual FGFs on living cells reveals novel modes of molecular diffusion at the cell surface and of oligomerisation of signalling complexes"
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| 9:50 am - 10:00 am | Discussion | 
| 10:00 am | Coffee Break | 
| 10:30 am - 10:50 am | Walter Nickel (University of Heidelberg, Germany) "Molecular analysis of the unconventional secretory pathway of FGF2"
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| 10:50 am - 11:00 am | Discussion | 
| 11:00 am - 11:20 am | John Heath (University of Birmingham, UK) "Architecture and dynamics of the FGF signaling pathway(s)"
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| 11:20 am - 11:30 am | Discussion | 
| 11:30 am - 11:50 am | Akira Imamoto (University of Chicago, USA) "Probing protein-protein interactions for an FGFR1/2 signaling feedforward loop"
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| 11:50 am - 12:00 pm | Discussion | 
| 12:00 pm - 12:10 pm | Andrew Beenken (New York University, School of Medicine, USA) "Structural basis for FGF-FGFR binding specificity and promiscuity"
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| 12:10 pm - 12:15 pm | Discussion | 
| 12:15 pm - 12:25 pm | Arno Muller (University of Dundee, UK) "The Drosophila nesthocker mutation reveals a novel link between O-GlcNAcylation and Fibroblast Growth Factor signalling"
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| 12:25 pm - 12:30 pm | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 6:00 pm | Poster Session | 
| 6:00 pm | Dinner | 
| 7:30 pm - 9:30 pm | Interactions of FGFs with other signaling pathways | 
|  | Discussion Leader: Gail Martin (University of California, San Francisco, USA) | 
| 7:30 pm - 7:50 pm | Claudio Basilico (New York University School of Medicine, New York, USA) "FGF induces Sox2 to promote osteoblast self-renewal"
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| 7:50 pm - 8:00 pm | Discussion | 
| 8:00 pm - 8:10 pm | Hichem Miraoui (INSERM U606, Paris, France) "Increased EGF and PDGF-alpha receptor signaling by mutant FGF receptor 2 contributes to osteoblast dysfunction in Apert craniosynostosis"
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| 8:10 pm - 8:15 pm | Discussion | 
| 8:15 pm - 8:25 pm | Toru Imamura (National Institute of Advanced Industrial Science and Technology, Tsukaba, Japan) "Association between FGF18 signaling and resting phase of hair growth"
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| 8:25 pm - 8:30 pm | Discussion | 
| 8:30 pm - 8:50 pm | Irma Thesleff (University of Helsinki, Finland) "Integration of FGF and other signal pathways during tooth development"
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| 8:50 pm - 9:00 pm | Discussion | 
| 9:00 pm - 9:20 pm | David Ornitz (Washington University, St. Louis, USA) "Intracellular FGFs: conserved structure, unique function"
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| 9:20 pm - 9:30 pm | Discussion | 
| TUESDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am - 12:30 pm | FGFs in Development | 
|  | Discussion Leader: David Ornitz (Washington University, St. Louis, USA) | 
| 9:00 am - 9:20 am | Olivier Pourquié (Institute of Genetics and Molecular and Cellular Biology, Strasbourg, France) "Role of FGF signaling in patterning the vertebrate embryonic axis"
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| 9:20 am - 9:30 am | Discussion | 
| 9:30 am - 9:50 am | Joseph Yost (University of Utah, Salt Lake City, USA) "FGF signaling pathways and HSPG fine structures regulate cilia functions in development"
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| 9:50 am - 10:00 am | Discussion | 
| 10:00 am | Coffee Break | 
| 10:30 am - 10:50 am | Deborah Yelon (University of California, San Diego, USA) "Effects of FGF signaling on the zebrafish heart fields"
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| 10:50 am - 11:00 am | Discussion | 
| 11:00 am - 11:10 am | Judith Neugebauer (University of Utah, Salt Lake City, USA) "FGF signaling controls brain laterality in early embryo development"
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| 11:10 am - 11:15 am | Discussion | 
| 11:15 am - 11:25 am | Angela Stathopoulos (Caltech, Pasadena, USA) "Mesoderm migration in Drosophila is a multi-step process requiring two FGF ligands"
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| 11:25 am - 11:30 am | Discussion | 
| 11:30 am - 11:50 am | Gail Martin (University of California, San Francisco, USA) "Regulation of oriented cell division by FGF signaling in airway morphogenesis"
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| 11:50 am - 12:00 pm | Discussion | 
| 12:00 pm - 12:10 pm | Sung-Ho Huh (Washington University, St. Louis, USA) "FGF9 subfamily regulates organ of Corti development"
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| 12:10 pm - 12:15 pm | Discussion | 
| 12:15 pm - 12:25 pm | Albert Basson (King's College, London, UK) "Sprouty genes function as negative regulators of the FGF signalling pathway during cerebellar development"
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| 12:25 pm - 12:30 pm | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 6:00 pm | Poster Session | 
| 6:00 pm | Dinner | 
| 7:30 pm - 9:30 pm | FGFs in the Nervous System | 
|  | Discussion Leader: Klaus Unsicker (University of Freiburg, Germany) | 
| 7:30 pm - 7:50 pm | Steve Wilson (University College London, UK) "A role for FGF signalling in the establishment of brain asymmetry"
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| 7:50 pm - 8:00 pm | Discussion | 
| 8:00 pm - 8:10 pm | James Li (University of Connecticut, Farmington, USA) "Interactions among different FGF8 splice forms in the control of midbrain-hindbrain development"
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| 8:10 pm - 8:15 pm | Discussion | 
| 8:15 pm - 8:35 pm | Juha Partanen (University of Helsinki, Finland) "FGF signalling and neuronal development in the embryonic midbrain"
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| 8:35 pm - 8:45 pm | Discussion | 
| 8:45 pm - 9:05 pm | Klaus Unsicker (University of Freiburg, Germany) "Regulation of astroglial functions and neural progenitor cells by FGF2"
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| 9:05 pm - 9:15 pm | Discussion | 
| 9:15 pm - 9:25 pm | Mohammad Hajihosseini (School of Biological Sciences, Norwich, UK) "FGF10 expressing tanycytes in the adult hypothalamus resemble neural stem cells and generate both neurons and glia in vivo"
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| 9:25 pm - 9:30 pm | Discussion | 
| WEDNESDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am - 12:30 pm | Endocrine FGFs | 
|  | Discussion Leader: Steven Kliewer (University of Texas, Dallas, USA) | 
| 9:00 am - 9:20 am | Wallace McKeehan (Texas A&M Health Science Center, Houston) "Beta-Klotho directs FGFR4 and FGFR1 signaling to metabolism and tumor suppression"
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| 9:20 am - 9:30 am | Discussion | 
| 9:30 am - 9:50 am | Nobuyuki Itoh (Kyoto University, Japan) "Roles of FGF21 signaling in energy metabolism"
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| 9:50 am - 10:00 am | Discussion | 
| 10:00 am | Coffee Break | 
| 10:30 am - 10:40 am | Yang Li (Amgen Inc., South San Francisco, USA) "FGF19 activates different FGFRs to control distinct biological responses"
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| 10:40 am - 10:45 am | Discussion | 
| 10:45 am - 11:05 am | Beate Lanske (Harvard Medical School, Boston, USA) "FGF23: an endocrine hormone derived from bone"
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| 11:05 am - 11:15 am | Discussion | 
| 11:15 am - 11:35 am | Makoto Kuro-O (University of Texas, Dallas, USA) "Endocrine FGFs and Klothos"
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| 11:35 am - 11:45 am | Discussion | 
| 11:45 am - 12:05 pm | Yo-Ishi Nabeshima (Kyoto University, Japan) | 
| 12:05 pm - 12:15 pm | Discussion | 
| 12:15 pm - 12:25 pm | Barbara Haenzi (Friedrich Miescher Laboratories, Basel, Switzerland) "MEMO, a novel downstream effector of the FGFR pathway"
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| 12:25 pm - 12:30 pm | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 6:00 pm | Poster Session | 
| 6:00 pm | Dinner | 
| 7:30 pm - 9:30 pm | FGFs in Genetic / Developmental Disease | 
|  | Discussion Leader: Bradley Olwin (University of Colorado Boulder, USA) | 
| 7:30 pm - 7:50 pm | Marja Hurley (University of Connecticut, Farmington, USA) "Nuclear FGF2 isoforms are novel regulators of phosphate homeostasis"
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| 7:50 pm - 8:00 pm | Discussion | 
| 8:00 pm - 8:10 pm | Suzi Mansour (University of Utah, Salt Lake City, USA) "Genetic rescue of hearing loss in a mouse model of Muenke syndrome (FGFR3 P244R)"
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| 8:10 pm - 8:15 pm | Discussion | 
| 8:15 pm - 8:25 pm | Richard Grose (Institute of Cancer, Barts and The London School of Medicine and Dentistry, London, UK) "Insights from the FGF22 knockout mouse"
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| 8:25 pm - 8:30 pm | Discussion | 
| 8:30 pm - 8:50 pm | Andrew Wilkie (University of Oxford, UK) "Selfish FGF receptor mutations and spermatogenesis"
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| 8:50 pm - 9:00 pm | Discussion | 
| 9:00 pm - 9:20 pm | Nelly Pitteloud (Massachusetts General Hospital, Boston, USA) "Role of FGF signaling in the neuroendocrine control of reproduction"
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| 9:20 pm - 9:30 pm | Discussion | 
| THURSDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am - 12:30 pm | FGFs in Tissue Repair, Regeneration and Remodelling | 
|  | Discussion Leader: Andrew Wilkie (University of Oxford, UK) | 
| 9:00 am - 9:20 am | Saverio Bellusci (University of Southern California, Los Angeles, USA) "Expected and unexpected roles for fibroblast growth factor 10 in development and repair"
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| 9:20 am - 9:30 am | Discussion | 
| 9:30 am - 9:50 am | Michael Simons (Yale University, New Haven, USA) "FGF signaling in the endothelium"
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| 9:50 am - 10:00 am | Discussion | 
| 10:00 am | Coffee Break | 
| 10:30 am - 10:50 am | George Cotsarelis (University of Pennsylvania, Philadelphia, USA) "FGFs in hair follicle neogenesis following wounding"
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| 10:50 am - 11:00 am | Discussion | 
| 11:00 am - 11:10 am | Ariel Arthur (Glasgow Biomedical Research Center, Glasgow, UK) "The role of fibroblast growth factor-9 in chronically demyelinated multiple sclerosis lesions"
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| 11:10 am - 11:15 am | Discussion | 
| 11:15 am - 11:35 am | Bradley Olwin (University of Colorado, Boulder, USA) "A requirement for FGF Receptor 1 in skeletal muscle stem cell self-renewal and muscle regeneration"
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| 11:35 am - 11:45 am | Discussion | 
| 11:45 am - 11:55 am | Janet Bodmer (University of Cincinnati, USA) "The alpha isoform of PKC is necessary for low molecular weight fibroblast growth factor 2-mediated cardioprotection"
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| 11:55 am - 12:00 pm | Discussion | 
| 12:00 pm - 12:10 pm | Pierre Fons (Sanofi-Aventis, Toulouse, France) "SAR106881, a fibroblast growth factor receptor agonist aimed at improving peripheral vascularization and wound healing and at reducing neuropathic pain"
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| 12:10 pm - 12:15 pm | Discussion | 
| 12:15 pm - 12:25 pm | Christoph Ladel (Merck Serono Research, Geneva, Switzerland) "FGF18 evaluated in a translational dog model of osteoarthritis and relation to clinical settings"
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| 12:25 pm - 12:30 pm | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 6:00 pm | Poster Session | 
| 6:00 pm | Dinner | 
| 7:00 pm - 7:35 pm | Business Meeting | 
|  | (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) | 
|  | Afterwards: Introduction of an FGF website by Tomoko Iwata | 
| 7:35 pm - 9:30 pm | FGFs in Cancer | 
|  | Discussion Leader: Judith Abraham (Novartis Institutes for BioMedical Research, Emeryville, USA) | 
| 7:30 pm - 7:55 pm | Fen Wang (Texas A&M Health Science Center, Houston, USA) "The FGF signaling axis in prostate development and tumorigenesis"
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| 7:55 pm - 8:05 pm | Discussion | 
| 8:05 pm - 8:20 pm | Pamela Pollock (The Translational Genomics Research Institute, Phoenix, USA) "FGFR2 in endometrial cancer - receptor activation, inhibition and resistance to FGFR tyrosine kinase inhibitors"
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| 8:20 pm - 8:25 pm | Discussion | 
| 8:25 pm - 8:35 pm | Tomoko Iwata (University of Glasgow, UK) "Towards the mouse model of bladder cancer with FGFR3 mutations; co-operators and tissue-specific signaling"
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| 8:30 pm - 8:40 pm | Discussion | 
| 8:40 pm - 9:00 pm | Jing Qing (Genentech Inc., South San Francisco, USA) "Antibody targeting of FGFR3 in human cancer"
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| 9:00 pm - 9:10 pm | Discussion | 
| 9:10 pm - 9:25 pm | Adam Cheuk (NIH/NCI, Bethesda, USA) "Activating mutations of FGFR4 in rhabdomyosarcoma"
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| 9:25 pm - 9:30 pm | Discussion | 
| FRIDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am | Depart |