Conference Description
The Frontotemporal Dementia and Related Rare Dementias GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes an array of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.
FTD is the most common pre-senile dementia under the age of 60. Highly distinctive from Alzheimer’s Disease (AD) and Parkinson’s Disease (PD), FTD manifests as personality changes, impaired language production and other executive function abnormalities due to progressive focal degeneration of the frontal and temporal lobes. Other rare dementias with intersecting pathobiology include vascular dementia, Lewy body disease, post-viral dementias, and chronic traumatic encephalopathy associated with brain injury. FTD and other rare dementias are much less well understood at the mechanistic level than AD and PD.
The inaugural Gordon Conference on Frontotemporal Dementia (FTD) and Related Rare Dementias: Pathology, Molecular Pathogenesis and Therapeutic Landscape will highlight exciting recent discoveries across the spheres of basic, translational and clinical investigation. The meeting will highlight the evolving nosology of these disorders, biomarker development and the mechanistic basis for genetic and sporadic forms of disease. Particular focus will be on shared and distinctive features of these diseases. Invited speakers will be encouraged to present unpublished work and explore collaborative opportunities to catalyze the development of effective treatments for these disorders. Attendees are encouraged to submit abstracts as the final program will include many talks selected from these submissions.
The topics, speakers, and discussion leaders for the conference sessions are displayed below. The conference chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by October 18, 2025. Please check back for updates.
Keynote Session: FTD and Related Dementias: Clinical Updates on Genetics, Neuropathology and Imaging
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Biomarkers and the Genotype-Phenotype Connection
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Neuroinflammation and Spread of Disease
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Lysosome Biology and Mechanisms in FTD
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Structural Biology of FTD
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Contributions of Lipid Metabolism to FTD and Other Neurodegenerative Diseases
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TDP-43 and LATE
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Vascular Dementia and the Blood Brain Barrier
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Keynote Session: Clinical Translation and Therapeutics in FTD
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