1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Chromatin and Nuclear Dynamics During DNA Repair
Katherine Baillie (The University of British Columbia, Canada)
3:45 pm - 3:50 pm
Introduction by Discussion Leader
3:50 pm - 4:20 pm
Irene Chiolo (University of Southern California, United States) "Highways for Heterochromatic Double Strand Break Repair"
4:20 pm - 4:30 pm
4:30 pm - 6:00 pm
6:00 pm - 7:00 pm
7:30 pm - 9:30 pm
Genomic Integrity, Chromatin and Nuclear Dynamics during DNA Repair
Jessica Kelliher (University of Arkansas for Medical Sciences, United States)
7:30 pm - 7:45 pm
Sangin Kim (Center for Genomic Integrity, Institute for basic Science (IBS), South Korea) "Unprocessed Ub-PCNA Promotes Break-Induced Replication at Telomeres in ATAD5-deficient ALT Cancer Cells"
7:45 pm - 7:50 pm
7:50 pm - 8:05 pm
Radoslaw Szmyd (Children's Medical Research Institute (CMRI), Australia) "Double-Strand Break Repair Pathway Choice Dictates Cell Death Outcomes After Ablative Radiotherapy"
8:05 pm - 8:10 pm
8:10 pm - 8:25 pm
Gonen Memisoglu (The University of Chicago, United States) "Elucidating Mechanisms of Non-Canonical CDK8 Function in DNA Damage Signaling"
8:25 pm - 8:30 pm
8:30 pm - 8:45 pm
Marton Kovacs (Institut Curie, France) "DNA Damage-Induced Nuclear Envelope Rupture: a New Cancer Vulnerability"
8:45 pm - 8:50 pm
8:50 pm - 9:05 pm
Diana Llerena Schiffmacher (Erasmus MC, The Netherlands) "Protein Dynamics, Functioning and Partners in TC-NER: Following CSB and CSA at an Endogenous Level"
9:05 pm - 9:10 pm
9:10 pm - 9:25 pm
Anthony Sanchez (University of Texas at Austin, United States) "The Histone Demethylase KDM5A Promotes DNA Repair Activities Including Transcriptional Silencing via Poly(ADP-Ribose) Binding and macroH2A"
9:25 pm - 9:30 pm
7:30 am - 8:30 am
9:00 am - 11:00 am
DNA Repair by Homologous Recombination, During Transcription and Replication Stress
Pierce Longmire (University of Arizona, United States)
9:00 am - 9:15 am
Arindam Datta (The Perelman School of Medicine at the University of Pennsylvania, United States) "Autologous K63-Deubiquitylation Within the BRCA1-A Complex Licenses DNA Damage Recognition"
9:15 am - 9:20 am
9:20 am - 9:35 am
Nam woo KIM (Center for genomic integrity, Institute for basic science (IBS-CGI)., South Korea) "Short-Range End Resection Requires Proper PCNA Unloading for Faithful Homologous Recombination Repair"
9:35 am - 9:40 am
9:40 am - 9:55 am
Elizabeth Irvin (North Carolina State University, United States) "R-Loop-Mediated Recruitment of Cohesin and CTCF as a Potential Regulator of Genome Structure and DNA Repair"
9:55 am - 10:00 am
10:00 am - 10:15 am
Eunjin Ryu (Center for Genomic Integrity, Institute of Basic Science / Ph.D. Candidate, South Korea) "ATAD5 Functions as a Regulatory Platform for Ub-PCNA De-ubiquitination"
10:15 am - 10:20 am
10:20 am - 10:35 am
Benjamin Orris (Johns Hopkins University, United States) "Phosphorylation of SAMHD1 Thr592 Increases C-Terminal Domain Dynamics, Tetramer Dissociation, and ssDNA Binding Kinetics"
10:35 am - 10:40 am
10:40 am - 10:55 am
Raissa Ng (University of Hong Kong, Hong Kong SAR China) "Role of ARIP4 in Transcription & DNA Double-Strand Break Metabolism"
10:55 am - 11:00 am
11:00 am - 12:30 pm
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
1:30 pm - 2:30 pm
Mentorship Component: Career Paths for Scientists
Dipika Gupta (NYU School of Medicine, New York, New York., United States)
1:30 pm - 2:30 pm
Career Paths for Scientists
Tanya Paull (University of Texas at Austin, United States)
Irene Chiolo (University of Southern California, United States)
Gaelle Legube (CBI, CNRS, University of Toulouse, France)
2:30 pm - 3:00 pm
Fill in GRS Evaluation Forms