Sunday
|
2:00 pm - 8:00 pm |
Arrival and Check-in
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 7:40 pm |
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
|
7:40 pm - 9:30 pm |
Early Embryogenesis: The Origin of the Germline
Discussion Leader: Ian Chambers (University of Edinburgh, United Kingdom)
|
7:40 pm - 7:45 pm |
Introduction by Discussion Leader
|
7:45 pm - 8:10 pm |
Magdalena Zernicka-Goetz (University of Cambridge, United Kingdom)
"Building the Mammalian Embryo In Vivo and In Vitro"
|
8:10 pm - 8:20 pm |
Discussion
|
8:20 pm - 8:45 pm |
Takashi Hiiragi (European Molecular Biology Laboratory (EMBL), Germany)
"Self-Organization in Mouse Development"
|
8:45 pm - 8:55 pm |
Discussion
|
8:55 pm - 9:20 pm |
Jianping Fu (University of Michigan, Ann Arbor, USA)
"Synthetic Human Embryo-Like Structures: A New Paradigm for Human Embryology"
|
9:20 pm - 9:30 pm |
Discussion
|
Monday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am - 12:30 pm |
Genetic Regulation of the Germline
Discussion Leader: Josephine Bowles (The University of Queensland, Australia)
|
9:00 am - 9:05 am |
Introduction by Discussion Leader
|
9:05 am - 9:15 am |
Selected from Poster Abstracts: Walfred Tang (University of Cambridge, United Kingdom)
"A Critical but Divergent Role of PRDM14 in Human Primordial Germ Cell Fate Revealed by Inducible Degrons"
|
9:15 am - 9:20 am |
Discussion
|
9:20 am - 9:45 am |
Martin Matzuk (Baylor College of Medicine, USA)
"Targeting Spermatogenesis for Male Contraception"
|
9:45 am - 9:55 am |
Discussion
|
9:55 am - 10:05 am |
Selected from Poster Abstracts: Julia Spindel (The Babraham Institute, University of Cambridge / MRC Cambridge Stem Cell Institute, United Kingdom)
"The Role and Regulation of UHRF1 During Mammalian Embryogenesis"
|
10:05 am - 10:10 am |
Discussion
|
10:10 am - 10:40 am |
Group Photo / Coffee Break
|
10:40 am - 11:05 am |
Wei Li (Institute of Zoology, Chinese Academy of Sciences, China)
"Deciphering Allelic Imbalance and Its Role in Reproduction"
|
11:05 am - 11:15 am |
Discussion
|
11:15 am - 11:25 am |
Selected from Poster Abstracts: Man Zhang (University of Edinburgh, United Kingdom)
"Otx2 Heterozygosity Enables ESRRB to Induce PGC Differentiation Without Cytokines"
|
11:25 am - 11:30 am |
Discussion
|
11:30 am - 11:55 am |
Peter Koopman (The University of Queensland, Australia)
"Molecular Pathways of Mammalian Sex Determination"
|
11:55 am - 12:05 pm |
Discussion
|
12:05 pm - 12:15 pm |
General Discussion
|
12:15 pm - 12:30 pm |
Poster Previews
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 9:30 pm |
Female Germline Development
Discussion Leader: Lei Lei (University of Michigan, USA)
|
7:30 pm - 7:35 pm |
Introduction by Discussion Leader
|
7:35 pm - 8:00 pm |
Ji Wu (Shanghai Jiao Tong University, China)
"Epigenetic Regulation Mechanism in Differentiation of Female Germline Stem Cells"
|
8:00 pm - 8:10 pm |
Discussion
|
8:10 pm - 8:35 pm |
Evelyn Telfer (University of Edinburgh, United Kingdom)
"Growing Old Human Oocytes and Making New Ones In Vitro"
|
8:35 pm - 8:45 pm |
Discussion
|
8:45 pm - 9:10 pm |
Cai-Xia Yang (Northeast Agricultural University, China)
"Functional Investigation of Long Noncoding RNAs on Porcine Oocyte Maturation and Early Embryo Development"
|
9:10 pm - 9:20 pm |
Discussion
|
9:20 pm - 9:30 pm |
General Discussion
|
Tuesday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am - 12:30 pm |
Single Cell Analyses of Germ Cell Development
Discussion Leader: Blanche Capel (Duke University, USA)
|
9:00 am - 9:05 am |
Introduction by Discussion Leader
|
9:05 am - 9:30 am |
Fuchou Tang (Peking University, China)
"Decoding the Gene Regulation Network of Human Germline Cells by Single Cell Functional Genomics Approach"
|
9:30 am - 9:40 am |
Discussion
|
9:40 am - 10:05 am |
Kikue Tachibana (IMBA - Institute of Molecular Biotechnology, Austrian Academy of Sciences, Austria)
"New Insights into the Causes of the Maternal Age Effect"
|
10:05 am - 10:15 am |
Discussion
|
10:15 am - 10:45 am |
Coffee Break
|
10:45 am - 10:55 am |
Selected from Poster Abstracts: Tsotne Chitiashvili (University of California, Los Angeles, USA)
"Human Primordial Germ Cells Recapitulate X Chromosome Dynamics of Human Pre-Implantation Embryos"
|
10:55 am - 11:00 am |
Discussion
|
11:00 am - 11:25 am |
Sue Hammoud (University of Michigan, USA)
"The Power of One: Single Cell Sequencing Identifies an Unexpected Somatic Cell Progenitor"
|
11:25 am - 11:35 am |
Discussion
|
11:35 am - 12:00 pm |
Brian Hermann (University of Texas at San Antonio, USA)
"Identifying Spermatogonial Stem Cells and Their Regulatory Framework with Single-Cell Transcriptomics"
|
12:00 pm - 12:10 pm |
Discussion
|
12:10 pm - 12:15 pm |
General Discussion
|
12:15 pm - 12:30 pm |
Poster Previews
|
12:30 pm - 1:30 pm |
Lunch
|
2:00 pm - 4:00 pm |
Poster Session
|
4:00 pm - 6:00 pm |
Environmental Impacts on the Germline
Discussion Leader: Patricia Hunt (Washington State University, USA)
|
4:00 pm - 4:05 pm |
Introduction by Discussion Leader
|
4:05 pm - 4:30 pm |
Qi Chen (University of California, Riverside, USA)
"Sperm RNA Code: How Many More Secrets in Programming Offspring Phenotypes?"
|
4:30 pm - 4:40 pm |
Discussion
|
4:40 pm - 5:05 pm |
Adam Watkins (University of Nottingham, United Kingdom)
"Dads, Diet and Disease: The Paternal Programming of Offspring Health"
|
5:05 pm - 5:15 pm |
Discussion
|
5:15 pm - 5:40 pm |
Michael Skinner (Washington State University, USA)
"Environmental Impacts on the Epigenetic Transgenerational Inheritance of Sperm Epimutations and Their Developmental Origins"
|
5:40 pm - 5:50 pm |
Discussion
|
5:50 pm - 6:00 pm |
General Discussion
|
6:00 pm - 7:00 pm |
Dinner
|
Wednesday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am - 12:30 pm |
Spermatogonial Stem Cells and Their Niche
Discussion Leader: Jon Oatley (Washington State University, USA)
|
9:00 am - 9:05 am |
Introduction by Discussion Leader
|
9:05 am - 9:15 am |
Selected from Poster Abstracts: Robin Friedman (Ohana Biosciences, USA)
"Widespread Haploid-Biased Gene Expression in Mammalian Spermatogenesis Associated with Frequent Selective Sweeps and Evolutionary Conflict"
|
9:15 am - 9:20 am |
Discussion
|
9:20 am - 9:45 am |
Bradley Cairns (University of Utah, USA)
"The Human Testis Transcriptional Cell Atlas"
|
9:45 am - 9:55 am |
Discussion
|
9:55 am - 10:05 am |
Selected from Poster Abstracts: Julien Legrand (Monash University, Australia)
"Role of the RNA Helicase DDX5 in Spermatogonial Maintenance and Function"
|
10:05 am - 10:10 am |
Discussion
|
10:10 am - 10:40 am |
Coffee Break
|
10:40 am - 11:05 am |
Xin Chen (Johns Hopkins University, USA)
"Asymmetry from Symmetry or Symmetry from Asymmetry?"
|
11:05 am - 11:15 am |
Discussion
|
11:15 am - 11:25 am |
Selected from Poster Abstracts: Aya Uchida (The University of Tokyo, Japan)
"Non-Cell Autonomous Regionalization of Sertoli Valve Niche in the Terminal Segment of the Seminiferous Tubules of Mouse Testes"
|
11:25 am - 11:30 am |
Discussion
|
11:30 am - 11:55 am |
Jan-Bernd Stukenborg (Karolinska Institutet, Sweden)
"Male Germ Stem Cells, Their Niche and Potential In Vitro"
|
11:55 am - 12:05 pm |
Discussion
|
12:05 pm - 12:15 pm |
Selected from Poster Abstracts: Cameron Berry (Stanford University, USA)
"Developmentally Regulated Differential Cleavage of Transcript 3' Ends Controls a Switch in Proteins Expressed as Male Germline Cells Transition from Proliferation to Differentiation"
|
12:15 pm - 12:20 pm |
Discussion
|
12:20 pm - 12:30 pm |
General Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:00 pm - 7:30 pm |
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
|
7:30 pm - 9:30 pm |
Epigenetic Programming of Germline Development
Discussion Leader: Amander Clark (University of California, Los Angeles, USA)
|
7:30 pm - 7:35 pm |
Introduction by Discussion Leader
|
7:35 pm - 8:00 pm |
Mitinori Saitou (Kyoto University, Japan)
"Mechanism and Reconstitution In Vitro of Human Germ Cell Development"
|
8:00 pm - 8:10 pm |
Discussion
|
8:10 pm - 8:35 pm |
Makoto Tachibana (Graduate School of Frontier Biosciences, Osaka University, Japan)
"Epigenetic Regulation of Spermatogonial Development by Histone Demethylation"
|
8:35 pm - 8:45 pm |
Discussion
|
8:45 pm - 9:10 pm |
Patrick Western (Hudson Institute of Medical Research, Australia)
"Germline Epigenetics: Polycomb Regulated Investment in Offspring Futures"
|
9:10 pm - 9:20 pm |
Discussion
|
9:20 pm - 9:30 pm |
General Discussion
|
Thursday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am - 12:30 pm |
Technological Advances in Germ Cell Research
Discussion Leader: Susana Chuva de Sousa Lopes (Leiden University Medical Center, The Netherlands)
|
9:00 am - 9:05 am |
Introduction by Discussion Leader
|
9:05 am - 9:15 am |
Selected from Poster Abstracts: Swati Sharma (Centre for Reproductive Medicine and Andrology, University of Münster, Germany)
"Testes-on-Chip Model for In Vitro Primate Spermatogenesis"
|
9:15 am - 9:20 am |
Discussion
|
9:20 am - 9:45 am |
Irina Larina (Baylor College of Medicine, USA)
"Regulation of Gametes and Preimplantation Embryos by Oviduct Environment: What Can We Learn from In Vivo Imaging"
|
9:45 am - 9:55 am |
Discussion
|
9:55 am - 10:05 am |
Selected from Poster Abstracts: Magdalena Wagner (Karolinska Institutet, Sweden)
"Characterization of Human Ovarian Tissue Cells"
|
10:05 am - 10:10 am |
Discussion
|
10:10 am - 10:40 am |
Coffee Break
|
10:40 am - 11:05 am |
Goro Yoshizaki (Tokyo University of Marine Science and Technology, Japan)
"Germ Cell Transplantation in Fish: Current Status and Future Prospects"
|
11:05 am - 11:15 am |
Discussion
|
11:15 am - 11:25 am |
Selected from Poster Abstracts: Daisylyn Senna Tan (The University of Hong Kong, Hong Kong SAR China)
"Elucidating the Mechanism for High Performance Cell Fate Reprogramming by an Artificially Evolved POU Factor"
|
11:25 am - 11:30 am |
Discussion
|
11:30 am - 11:55 am |
Masahito Ikawa (Osaka University, Japan)
"CRISPR/Cas9 Mediated Genome Editing and Its Application for the Study of Fertilization"
|
11:55 am - 12:05 pm |
Discussion
|
12:05 pm - 12:15 pm |
Selected from Poster Abstracts: Kanako Ikami (University of Michigan, USA)
"Branched Germline Cysts Formation and Fragmentation in Mouse Gametogenesis"
|
12:15 pm - 12:20 pm |
Discussion
|
12:20 pm - 12:30 pm |
General Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Natural and Induced Mutations in the Germline
Discussion Leader: John McCarrey (University of Texas at San Antonio, USA)
|
4:00 pm - 4:05 pm |
Introduction by Discussion Leader
|
4:05 pm - 4:30 pm |
Itai Yanai (New York University Langone Health, USA)
"Widespread Transcriptional Scanning in Testes Modulates Gene Evolution Rates"
|
4:30 pm - 4:40 pm |
Discussion
|
4:40 pm - 5:05 pm |
Anne Goriely (University of Oxford, United Kingdom)
"Selfish Testes, New Mutations and Human Disease"
|
5:05 pm - 5:15 pm |
Discussion
|
5:15 pm - 5:40 pm |
Jacob Mueller (University of Michigan Medical School, USA)
"A Mus Lineage-Specific Gene Family Is Essential for Male Fertility and Equalized Sex Ratio"
|
5:40 pm - 5:50 pm |
Discussion
|
5:50 pm - 6:00 pm |
General Discussion
|
6:00 pm - 7:00 pm |
Dinner
|
Friday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am |
Departure
|