Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Regulation of Glycosylation
Discussion Leader: Nicholas Riley (Stanford University, United States)
3:45 pm - 4:00 pm
Andrew Alexander (ETH Zürich, Switzerland)
"Structural and Functional Analysis of ALG9: a Human Endoplasmic Reticulum a1,2-Mannosyltransferase"
4:00 pm - 4:05 pm
Discussion
4:05 pm - 4:20 pm
L?la Fagbami (University of Georgia, United States)
"Elucidating the Mechanism of N-linked Glycosylation in Human Malaria Parasites"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Chemical and Molecular Analysis of Glycosylation
Discussion Leader: Fiona Kearns (University of California, San Diego, United States)
7:30 pm - 7:45 pm
Sarah Lowery (Yale University, United States)
"Coupled MALDI-MSI and LC-MS for Comprehensive O-Glycoproteomic Analysis of FFPE Mucinous Tumor Samples"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Jessica Stark (Stanford University, United States)
"Antibody-lectin Chimeras for Glyco-immune Checkpoint Blockade"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Mana Mukherjee (National Institutes of Health, United States)
"1,3-Pr2 -6-OTs GlcNAlk as bioorthogonal precursor for specific labeling of N-glycan hybrid structure"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Jaclyn Swan (UCSD, United States)
"The Sialome of the Human Retina"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Tiandi Yang (Harvard Medical School, United States)
"An Extra ECM-binding Matriglycan on Dystroglycan"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Nicholas Riley (Stanford University, United States)
"Deciphering O-glycoprotease Substrate Preferences with O-Pair Search"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Glycans in Health and Disease
Discussion Leader: Jaclyn Swan (UCSD, United States)
9:00 am - 9:15 am
Priti Gupta (Gothenburg University, Sweden)
"Effects of Estrogen on IgG Glycosylation and Total Serum Protein Glycosylation"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Rohit Budhraja (Mayo clinic, United States)
"N-glycoproteomic Profiling of Phosphoglucomutase 2 (Pgm2) Knockout Mouse Heart Reveals Distinct Glycosylation Pattern"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Beatriz Calle (Francis Crick Institute, United Kingdom)
"A Chemical Biology Approach to Characterise the Glycoproteome of Breast Cancer"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Lauren Gandy (Rensselaer Polytechnic Institute, United States)
"Characterizing the interface of HSV-1 Glycoprotein D/heparan Sulfate and their Ternary Complex with Tau: Implications for Alzheimer’s Disease and Herpes"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Fiona Kearns (University of California, San Diego, United States)
"Atomic Scale Exploration of Respiratory Mucins and their Interactions with the SARS-CoV-2 Spike Glycoprotein"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Vienvilay Phandanouvong Lozano (University of California Berkeley, United States)
"Interrogating the Preferential Catabolism of Dietary Sialic Acids by the Gut Microbiota"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Careers in Glycoscience
Discussion Leaders: Kathirvel Alagesan (Max Planck Unit for the Science of Pathogens, Germany) and Simon Wisnovsky (Stanford University, United States)
1:30 pm - 2:30 pm
Panel Discussion
Careers in Glycoscience
Nancy Dahms (Medical College of Wisconsin, United States)
Lance Wells (University of Georgia, United States)
Daniel Kolarich (Institute for Glycomics, Griffith University, Australia)
Karin Hoffmeister (Versiti Blood Research Institute, United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes