Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Career Development for Early Career Researchers
Dr. Karen Knudsen, director of the Sidney Kimmel Cancer Center - Jefferson Health and vice president/president-elect of the board of directors for Association of American Cancer Institutes will give a keynote presentation with advice for trainees and an overview of her experiences in becoming a leader in hormone-dependent cancers.
Discussion Leader: Catherine Sevigny (Georgetown University, USA)
3:45 pm - 4:20 pm
Karen Knudsen (Sidney Kimmel Cancer Center, Jefferson Health, USA)
"Career Development for Early Career Researchers"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Hormones that Drive Cancer Development and Metastasis
Discussion Leader: Stacey Joosten (Netherlands Cancer Institute, The Netherlands)
7:30 pm - 7:45 pm
Zannel Blanchard (University of Utah, USA)
"Estrogen-Independent Activity of Mutant Estrogen Receptor Alpha in Endometrial Cancer"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Eric Bolf (University of Vermont, USA)
"Thyroid Hormone Mediated Tumor Suppression in Anaplastic Thyroid Cancer"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Jamie Kutasovic (The University of Queensland, Australia)
"Alternative Oestrogen Regulated Transcription Driving Metastatic Colonisation of Gynaecological Organs"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Isabel Mayayo Peralta (Netherlands Cancer Institute, The Netherlands)
"Characterizing the Interplay Between Steroid Hormone Receptors in Breast Cancer"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Sayali Onkar (University of Pittsburgh School of Medicine, USA)
"Investigating the Immune Microenvironment of Primary Invasive Lobular Breast Carcinoma"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Jessica Pilsworth (BC Cancer, Canada)
"Genomic Characterization of Adult Type Granulosa Cell Tumours Reveals Mutations in Epigenetic Regulators"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Overcoming Drug Resistance in Hormone-Dependent Cancers
Discussion Leader: Justin Hwang (Dana Farber Cancer Institute, USA)
9:00 am - 9:15 am
Mark Daniel (University of Minnesota, USA)
"Wnt Enhanceosome Component TLE3 Functions as an AR Co-Regulator and Supports Anchorage-Independent Growth in AR Variant-Driven Prostate Cancer Models"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Rajdeep Das (University of California, San Francisco, USA)
"Investigating Kinesin Family Member 4A as a Novel Driver of Aggressive Prostate Cancer"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Simon Linder (Netherlands Cancer Institute, The Netherlands)
"Integrative Cistromic Profiling of High-Risk Prostate Cancer Before and After Neoadjuvant Enzalutamide Treatment"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Emmanuel Rosas (University of Colorado Anschutz Medical Campus, USA)
"TGFβ Crosstalk with Androgen Receptors in Triple-Negative Breast Cancer"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Nicole Traphagen (Dartmouth College, USA)
"Estrogen Therapy for Advanced Breast Cancer: Understanding the Mechanism of Action Leads to Strategies to Improve Response and Reduce Toxicity"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Thu Truong (University of Minnesota, USA)
"Steroid Receptor Co-Activators Reprogram Metabolic Pathways that Drive Luminal Breast Cancer Stemness"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Exploring Career Opportunities for Cancer Biologists
During this session, participants will be able to interact with a number of PhD-level career panelists. These panelists come from a variety of backgrounds, including academia, industry, and policy. Participants will be able to ask questions freely and engage in open discussions. Each panelist will offer a unique perspective and valuable advice for success for all of the early career scientists in attendance.
Discussion Leader: Evelyn Bordeaux (University of Colorado Anschutz Medical Campus, USA)
1:30 pm - 2:30 pm
Panel Discussion
Career Opportunities for Cancer Biologists
Courtney Andersen (AstraZeneca, USA)
Charlotte Bevan (Imperial College London, United Kingdom)
Jamie Holloway (Caris Life Sciences, USA)
Daniel Gioeli (University of Virginia, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
