Sunday
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2:00 pm - 9:00 pm |
Arrival and Check-in
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6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 7:40 pm |
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
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7:40 pm - 9:30 pm |
Keynote Session: Exploring Genome Perturbations in Health and Disease
Discussion Leader: Graham McVicker (Salk Institute for Biological Studies, USA)
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7:40 pm - 7:50 pm |
Opening Remarks
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7:50 pm - 8:00 pm |
Introduction by Discussion Leader
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8:00 pm - 8:35 pm |
Claudia Langenberg (University of Cambridge, United Kingdom and Berlin Institute of Health at Charité, Germany)
"Proteogenomic Studies of the Human Phenome"
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8:35 pm - 8:45 pm |
Discussion
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8:45 pm - 9:20 pm |
Janet Thornton (European Bioinformatics Institute (EMBL-EBI), United Kingdom)
"Using 3D Structures and Genetic Data to Interpret the Impact of Human Variants on Diseases"
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9:20 pm - 9:30 pm |
Discussion
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Monday
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7:30 am - 8:30 am |
Breakfast
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9:00 am - 12:30 pm |
Genome Variation and COVID-19
Discussion Leader: Benjamin Greenbaum (Memorial Sloan Kettering Cancer Center, USA)
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9:00 am - 9:10 am |
Introduction by Discussion Leader
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9:10 am - 9:40 am |
Dennis Ko (Duke University, USA)
"Rapid Cellular Screening of Human Genetic Resistance to Pathogens"
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9:40 am - 9:50 am |
Discussion
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9:50 am - 10:20 am |
Dmitry Korkin (Worcester Polytechnic Institute, USA)
"Unveiling Structure and Dynamics of SARS-CoV-2 via an Integrated Approach"
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10:20 am - 10:30 am |
Discussion
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10:30 am - 10:55 am |
Coffee Break
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10:55 am - 11:25 am |
Brent Richards (McGill University, Canada)
"Using Human Genetics to Identify Biomarkers for COVID-19"
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11:25 am - 11:35 am |
Discussion
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11:35 am - 12:05 pm |
Judith Blake (Jackson Labs, USA)
"Investigating the Genetics of COVID-19 and Severe Co-Morbidities"
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12:05 pm - 12:15 pm |
Discussion
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12:15 pm - 12:25 pm |
Late-Breaking Topic
|
12:25 pm - 12:30 pm |
Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
3:00 pm - 4:00 pm |
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Anna Panchenko (Queen's University, Canada) and Rachel Karchin (Johns Hopkins University, USA)
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4:00 pm - 6:00 pm |
Poster Session
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6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 9:30 pm |
Host Genome and Microbiome Interactions
Discussion Leader: Angela Poole (Cornell University, USA)
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7:30 pm - 7:40 pm |
Introduction by Discussion Leader
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7:40 pm - 8:10 pm |
Alexandra Zhernakova (University Medical Center Groningen, The Netherlands)
"Host Genetics and the Gut Microbiome"
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8:10 pm - 8:20 pm |
Discussion
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8:20 pm - 8:30 pm |
Late-Breaking Topic
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8:30 pm - 8:35 pm |
Discussion
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8:35 pm - 8:45 pm |
Late-Breaking Topic
|
8:45 pm - 8:50 pm |
Discussion
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8:50 pm - 9:20 pm |
Emily Davenport (Pennsylvania State University, USA)
"Using the Microbiome as a Proxy for the Environment in Genome-Wide Association Studies"
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9:20 pm - 9:30 pm |
Discussion
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Tuesday
|
7:30 am - 8:30 am |
Breakfast
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9:00 am - 12:30 pm |
Variants in Development and Early Onset Disease
Discussion Leader: Gary Hon (UT Southwestern Medical Center, USA)
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9:00 am - 9:10 am |
Introduction by Discussion Leader
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9:10 am - 9:40 am |
Elizabeth Bhoj (Children's Hospital of Philadelphia, USA)
"Advances in Novel Human Disease Gene Discovery"
|
9:40 am - 9:50 am |
Discussion
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9:50 am - 10:20 am |
Steven Brenner (University of California, Berkeley, USA)
"The Role of Exome Sequencing in Newborn Screening"
|
10:20 am - 10:30 am |
Discussion
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10:30 am - 10:55 am |
Coffee Break
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10:55 am - 11:25 am |
Wendy Chung (Columbia University, USA)
"Genomic Causes of Congenital Anomalies and the Clinical Applications of this Information"
|
11:25 am - 11:35 am |
Discussion
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11:35 am - 12:05 pm |
Lucia Peixoto (Washington State University, USA)
"Understanding Insomnia in Autism: From Phenotype to Genotype"
|
12:05 pm - 12:15 pm |
Discussion
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12:15 pm - 12:25 pm |
Late-Breaking Topic
|
12:25 pm - 12:30 pm |
Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 9:30 pm |
Human Diversity and Disease
Discussion Leader: Valerie Arboleda (UCLA, USA)
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7:30 pm - 7:40 pm |
Introduction by Discussion Leader
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7:40 pm - 8:10 pm |
Neil Hanchard (National Institutes of Health, USA)
"Genome Variation Leveraged from Diverse Ancestry"
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8:10 pm - 8:20 pm |
Discussion
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8:20 pm - 8:30 pm |
Late-Breaking Topic
|
8:30 pm - 8:35 pm |
Discussion
|
8:35 pm - 8:45 pm |
Late-Breaking Topic
|
8:45 pm - 8:50 pm |
Discussion
|
8:50 pm - 9:20 pm |
Eimear Kenny (Icahn School of Medicine at Mount Sinai, USA)
"Population Genetics in an Era of Genomic Health"
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9:20 pm - 9:30 pm |
Discussion
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Wednesday
|
7:30 am - 8:30 am |
Breakfast
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8:30 am - 9:00 am |
Group Photo
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9:00 am - 12:30 pm |
Cancer Genomics
Discussion Leader: Kuan-lin Huang (Icahn School of Medicine at Mount Sinai, USA)
|
9:00 am - 9:10 am |
Introduction by Discussion Leader
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9:10 am - 9:40 am |
Rachel Karchin (Johns Hopkins University, USA)
"Computational Tools to Predict Immunogenic Mutations"
|
9:40 am - 9:50 am |
Discussion
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9:50 am - 10:20 am |
Anna Panchenko (Queen's University, Canada)
"Epigenetic Cues in Cancer: DNA and Histone Modifications, Mutations and Beyond"
|
10:20 am - 10:30 am |
Discussion
|
10:30 am - 10:55 am |
Coffee Break
|
10:55 am - 11:25 am |
Mona Singh (Princeton University, USA)
"Discovery of Causal Mutations in Cancers"
|
11:25 am - 11:35 am |
Discussion
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11:35 am - 11:45 am |
Late-Breaking Topic
|
11:45 am - 11:50 am |
Discussion
|
11:50 am - 12:20 pm |
Adam Godzik (University of California, Riverside, USA)
"Understanding Cancer Mutation Through Three Dimensional Structures of Proteins and Their Networks"
|
12:20 pm - 12:30 pm |
Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:00 pm - 7:30 pm |
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
|
7:30 pm - 9:30 pm |
Computational Interpretation of Variants in the Clinical Context
Discussion Leader: Constantina Bakolitsa (University of California, Berkeley, USA)
|
7:30 pm - 7:40 pm |
Introduction by Discussion Leader
|
7:40 pm - 8:10 pm |
Sean Mooney (University of Washington, USA)
"From Variant Function to Implementation: Our Efforts to Develop and Bring Data Driven Methods to the Patient and Provider"
|
8:10 pm - 8:20 pm |
Discussion
|
8:20 pm - 8:30 pm |
Late-Breaking Topic
|
8:30 pm - 8:35 pm |
Discussion
|
8:35 pm - 8:45 pm |
Late-Breaking Topic
|
8:45 pm - 8:50 pm |
Discussion
|
8:50 pm - 9:20 pm |
Marylyn Ritchie (University of Pennsylvania, USA)
"Leveraging Electronic Health Records for Precision Medicine Research"
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9:20 pm - 9:30 pm |
Discussion
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Thursday
|
7:30 am - 8:30 am |
Breakfast
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9:00 am - 12:30 pm |
Genome Variation and Disease
Discussion Leader: Laura Conlin (University of Pennsylvania, USA)
|
9:00 am - 9:10 am |
Introduction by Discussion Leader
|
9:10 am - 9:40 am |
Douglas Fowler (University of Washington, USA)
"New Approaches for Evaluating Human Genetic Variants on a Massive Scale"
|
9:40 am - 9:50 am |
Discussion
|
9:50 am - 10:20 am |
Martin Kircher (University of Luebeck, Germany)
"Genome-Wide Ranking and Interpretation of Human Genetic Variation"
|
10:20 am - 10:30 am |
Discussion
|
10:30 am - 10:55 am |
Coffee Break
|
10:55 am - 11:25 am |
Predrag Radivojac (Northeastern University, USA)
"Towards a New Framework and Updated Recommendations for the use of Variant Interpretation Tools in Clinical Practice"
|
11:25 am - 11:35 am |
Discussion
|
11:35 am - 11:45 am |
Late-Breaking Topic
|
11:45 am - 11:50 am |
Discussion
|
11:50 am - 12:20 pm |
Itai Yanai (NYU Grossman School of Medicine, USA)
"Recurrence of Cancer Cell States Across Diverse Tumors and Their Interactions with the Microenvironment"
|
12:20 pm - 12:30 pm |
Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 9:30 pm |
Precision Medicine and Genomic Privacy
Discussion Leader: Gamze Gursoy (Columbia University, USA)
|
7:30 pm - 7:40 pm |
Introduction by Discussion Leader
|
7:40 pm - 8:10 pm |
Lucila Ohno-Machado (UCSD Health, USA)
"Federated Analyses of Human Genomes: Preserving Privacy While Expanding Researchers’ Access"
|
8:10 pm - 8:20 pm |
Discussion
|
8:20 pm - 8:30 pm |
Late-Breaking Topic
|
8:30 pm - 8:35 pm |
Discussion
|
8:35 pm - 8:45 pm |
Late-Breaking Topic
|
8:45 pm - 8:50 pm |
Discussion
|
8:50 pm - 9:20 pm |
Yves Moreau (Katholieke Universiteit, Belgium)
"Genomics and Mass Surveillance: How Do We Limit Abuses?"
|
9:20 pm - 9:30 pm |
Discussion
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Friday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am |
Departure
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