1:30 pm - 4:30 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
Antimalarial Drug Resistance and Drug Development
Abdoulaye Djimde (University of Sciences, Techniques and Technologies of Bamako, Mali) and David Khoury (Kirby Institute, University of New South Wales, Australia)
3:15 pm - 3:25 pm
Maria Rebelo (QIMR Berghofer Medical Research Institute, Australia) "Drug Testing in Volunteer Infection Studies: The Importance of Blood-Stage Parasite Viability in the Investigation of Antimalarial Drug Efficacy"
3:25 pm - 3:30 pm
3:30 pm - 3:40 pm
Monica Golumbeanu (Swiss Tropical and Public Health Institute, Switzerland) "Understanding Minimal Tool Properties Versus Operational Factors of New Malaria Interventions for Elimination: A Modelling Study"
3:40 pm - 3:45 pm
3:45 pm - 3:55 pm
Maëlle Duffey (Medicines for Malaria Venture, Switzerland) "Target Product Profiles for Malaria Medicines"
3:55 pm - 4:00 pm
4:00 pm - 5:30 pm
5:30 pm - 7:30 pm
Informing Vaccine Development Through Advances in Plasmodium Biology and Immunology
David Pulido-Gomez (University of Oxford, United Kingdom) and Prasanna Jagannathan (Stanford University, USA)
5:30 pm - 5:40 pm
Maureen Ty (Stanford University, USA) "Immunologic Profiles Defining Clinical States in Malaria"
5:40 pm - 5:45 pm
5:45 pm - 5:55 pm
Damian Oyong (Menzies School of Health Research, Australia) "Increased Magnitude and Breadth of Circulating TfH Activation in Adults Compared to Children with Malaria Is Associated with Higher Induction of Functional Antibodies"
5:55 pm - 6:00 pm
6:00 pm - 6:10 pm
Anton Goetz (National Institutes of Health, USA) "Altered Immune Responses in Malaria-Exposed Individuals"
6:10 pm - 6:15 pm
6:15 pm - 6:25 pm
Katrien Deroost (Francis Crick Institute, United Kingdom) "The Splenic Response to Blood-Stages of the Rodent Malaria Parasite,
Plasmodium chabaudi Following Vector Transmission"
6:25 pm - 6:30 pm
6:30 pm - 6:40 pm
Steven Kho (Menzies School of Health Research, Australia) "A Hidden Biomass of Non-Phagocytosed Asexual and Sexual Stages of
Plasmodium falciparum and P. vivax in the Human Spleen"
6:40 pm - 6:45 pm
6:45 pm - 6:55 pm
Hannah Fleckenstein (University Hospital Heidelberg, Germany) "Erythrocyte Remodeling in
Plasmodium falciparum Parasites During the Dry Season"
6:55 pm - 7:00 pm
7:00 pm - 7:10 pm
Saskia van der Boor (Radboud University Medical Center, The Netherlands) "Primary Porcine Hepatocytes as a Novel System for
Plasmodium falciparum Infection"
7:10 pm - 7:15 pm
7:15 pm - 7:25 pm
Eliana Cubillos (University of São Paulo, Brazil) "A
Plasmodium falciparum ApiAP2 Factor that Controls Var and Gametocyte Related Gene Transcription"
7:25 pm - 7:30 pm
8:00 pm - 9:00 pm
7:30 am - 8:30 am
9:00 am - 11:00 am
Vaccine Development / Mentorship Component: Careers in Science
Alexandra Spencer (University of Oxford, United Kingdom) and Faith Osier (Heidelberg University, Germany)
9:00 am - 9:10 am
Matthijs Jore (Radboud University Medical Center, The Netherlands) "Engineered Antibodies Against
Plasmodium Transmission from Man to Mosquito"
9:10 am - 9:15 am
9:15 am - 9:25 am
David Pulido-Gomez (University of Oxford, United Kingdom) "Characterization of Antimalarial Monoclonal Antibodies Reveals Synergistic Epitopes in the
Plasmodium falciparum RH5-CyRPA-Ripr Invasion Complex"
9:25 am - 9:30 am
9:30 am - 9:40 am
Carolyn Nielsen (Jenner Institute, University of Oxford, United Kingdom) "Superior Antigen-Specific T Follicular Helper (Tfh) Cell Responses to Blood-Stage Malaria Antigen RH5 Are Induced with a Protein/AS01 Vaccine Platform as Compared to Heterologous Viral Vectors"
9:40 am - 9:45 am
9:45 am - 9:55 am
Julio Ventocilla (U.S. Naval Medical Research Unit Six (NAMRU-6), Peru) "Development of
Plasmodium vivax Vietnam-IV Blood Challenge Model Using Aotus Nancymaee Monkeys for Evaluation of Blood-Stage Vaccine Candidates"
9:55 am - 10:00 am
10:00 am - 11:00 am
Careers in Science
Abdoulaye Djimde (University of Sciences, Techniques and Technologies of Bamako, Mali)
Jaline Gerardin (Northwestern University, USA)
Prasanna Jagannathan (Stanford University, USA)
Faith Osier (Heidelberg University, Germany)
11:00 am - 12:30 pm
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
1:30 pm - 2:30 pm
Understanding Malaria Transmission Dynamics
Jaline Gerardin (Northwestern University, USA) and Bilgo Etienne (IRSS/Centre Muraz, Burkina Faso)
1:30 pm - 1:40 pm
Zuleima Pava Imitola (QIMR Berghofer Medical Research Institute, Australia) "Investigating Human to Mosquito Transmission of Artemisinin-Resistant
P. falciparum Parasites in the Induced Blood Stage Malaria Model"
1:40 pm - 1:45 pm
1:45 pm - 1:55 pm
Lisette Meerstein-Kessel (Radboud University Medical Center, The Netherlands) "Performance of Transmission-Blocking Monoclonal Antibodies in DMFA and SMFA and Insights from Single-Oocyst Sequencing"
1:55 pm - 2:00 pm
2:00 pm - 2:10 pm
Gaëlle Neveu (Institute Cochin, France) "
Plasmodium falciparum Immature Gametocytes Development in Human Primary Erythroblasts"
2:10 pm - 2:15 pm
2:15 pm - 2:25 pm
Pablo Fontoura (University of São Paulo, Brazil) "Field Efficacy of Biolarvicides Applied in Fish Ponds for Malaria Vector Control in a High Transmission Area in the Brazilian Amazon"
2:25 pm - 2:30 pm
2:30 pm - 3:00 pm
Fill in GRS Evaluation Forms