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Mammalian Reproduction

Gordon Research Conference

Diverse Strategies to Advance Reproductive Science and Health

July 21 - 26, 2024

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Chairs Richard N. Freiman and Joan Jorgensen

Vice Chairs James M. Turner and Julie Kim

Contact Chairs

Rey Don Jaime Grand Hotel

Avinguda de l'Hotel

Castelldefels, Barcelona, Spain

Venue and Travel Information

Application Information

Applications for this meeting must be submitted by June 23, 2024. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the conference chair if more seats become available due to cancellations.

Conference Description

The Mammalian Reproduction GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

Related Meeting

This GRC will be held in conjunction with the "Mammalian Reproduction" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Conference Program

Sunday
2:00 pm - 9:00 pm	Arrival and Check-in
6:00 pm - 7:00 pm	Dinner
7:30 pm - 7:40 pm	Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm	Integrated Systems in Reproduction Discussion Leader: Indrani Bagchi (University of Illinois at Urbana-Champaign, United States)
7:40 pm - 7:45 pm	Introduction by Discussion Leader
7:45 pm - 8:10 pm	Adrian Erlebacher (University of California San Francisco, United States) "Mechanisms of Gestation Length Timing in Mice"
8:10 pm - 8:20 pm	Discussion
8:20 pm - 8:45 pm	Sue Hammoud (University of Michigan, United States) "Balancing Act: Equalizing Sex Specific CENP-A levels is Critical for Mammalian Embryogenesis"
8:45 pm - 8:55 pm	Discussion
8:55 pm - 9:20 pm	Humphrey Yao (National Institute of Environmental Health Sciences, NIEHS/NIH, United States) "Untangle the Sex Differentiation Multiverse of Embryonic Germ Cells and Gonadal Somatic Cells"
9:20 pm - 9:30 pm	Discussion
Monday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Sex Determination and Reproductive Tract Development Discussion Leader: Eric Pailhoux (INRAE - French National Research Institute for Agriculture, Food and the Environment, France)
9:00 am - 9:10 am	Introduction by Discussion Leader
9:10 am - 9:35 am	Carolina Jorgez (Baylor College of Medicine, United States) "Understanding Male Reproductive Tract Development Through Chromosomal Imbalances"
9:35 am - 9:45 am	Discussion
9:45 am - 10:10 am	Nitzan Gonen (Bar Ilan University, Israel) "How to Enhance Sex Determination?"
10:10 am - 10:20 am	Discussion
10:20 am - 10:30 am	Short Talk Selected from Poster Abstracts
10:30 am - 10:35 am	Discussion
10:35 am - 11:05 am	Coffee Break
11:05 am - 11:15 am	Short Talk Selected from Poster Abstracts
11:15 am - 11:20 am	Discussion
11:20 am - 11:45 am	Serge Nef (University of Geneva, Switzerland) "Studying Neglected Cell Populations of the Developing Gonads and Their Functions"
11:45 am - 11:55 am	Discussion
11:55 am - 12:05 pm	Short Talk Selected from Poster Abstracts
12:05 pm - 12:10 pm	Discussion
12:10 pm - 12:20 pm	Short Talk Selected from Poster Abstracts
12:20 pm - 12:25 pm	Discussion
12:25 pm - 12:30 pm	General Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:30 pm	Free Time
3:00 pm - 4:00 pm	The GRC Power Hour™ The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring. Organizers: Margaret Petroff (Michigan State University, United States) and Folami Ideraabdullah (University of North Carolina at Chapel Hill, United States)
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 8:00 pm	Bioengineering Approaches to Fertility Preservation and Development Discussion Leader: Benjamin Beaton (Genus plc, United States)
6:00 pm - 6:10 pm	Introduction by Discussion Leader
6:10 pm - 6:35 pm	Mijo Simunovic (Columbia University, United States) "Recapitulating Early Human Development with Stem Cells"
6:35 pm - 6:45 pm	Discussion
6:45 pm - 7:10 pm	Monica Laronda (Ann & Robert H Lurie Children's Hospital of Chicago (Lurie Children's), and Northwestern University, United States) "Bioengineering an Ovarian Microenvironment Informed by the Human Ovary BioMolecular Atlas"
7:10 pm - 7:20 pm	Discussion
7:20 pm - 7:45 pm	Yoni Baert (VUB, Belgium) "Latest Development in In Vitro Testis Modeling"
7:45 pm - 7:55 pm	Discussion
7:55 pm - 8:00 pm	General Discussion
8:00 pm - 9:00 pm	Dinner
Tuesday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Group Photo
9:00 am - 12:30 pm	Pushing the Envelope from Stem Cells to Gametes and Beyond Discussion Leader: Alta Charo (University of Wisconsin, United States)
9:00 am - 9:10 am	Introduction by Discussion Leader
9:10 am - 9:35 am	Amander Clark (University of California, Los Angeles, United States) "Engineering Ovarian Cells and Tissues from Pluripotent Stem Cells"
9:35 am - 9:45 am	Discussion
9:45 am - 10:10 am	Mitinori Saitou (Kyoto University, Japan) "Mechanism and In Vitro Reconstitution of Mammalian Germ Cell Development"
10:10 am - 10:20 am	Discussion
10:20 am - 10:30 am	Short Talk Selected from Poster Abstracts
10:30 am - 10:35 am	Discussion
10:35 am - 11:05 am	Coffee Break
11:05 am - 11:30 am	Magdalena Zernicka-Goetz (California Institute of Technology, United States) "The Principles of Self-Organization in Early Embryos and Their Stem Cell-Based Models"
11:30 am - 11:40 am	Discussion
11:40 am - 11:50 am	Short Talk Selected from Poster Abstracts
11:50 am - 11:55 am	Discussion
11:55 am - 12:20 pm	Andrew Pask (University of Melbourne, Australia) "Bringing Back the Past to Protect the Future; Deextinction of the Tasmanian Tiger"
12:20 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:30 pm	Free Time
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 8:00 pm	Environmental Impacts on Reproduction Discussion Leader: Pauliina Damdimopoulou (Karolinska Institutet, Sweden)
6:00 pm - 6:10 pm	Introduction by Discussion Leader
6:10 pm - 6:35 pm	Niels Skakkebaek (Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Denmark) "Testicular Germ Cell Cancer as a Late Symptom of Testicular Dysgenesis"
6:35 pm - 6:45 pm	Discussion
6:45 pm - 7:10 pm	Folami Ideraabdullah (University of North Carolina at Chapel Hill, United States) "Defining Mouse Germline Epigenetic Diversity Driven by Diet Composition"
7:10 pm - 7:20 pm	Discussion
7:20 pm - 7:45 pm	Daniel Spade (Brown University, United States) "Quantifying Low-Dose Toxicant Effects on Germ Cells: Phthalates and Ethylene Glycol Monomethyl Ether"
7:45 pm - 7:55 pm	Discussion
7:55 pm - 8:00 pm	General Discussion
8:00 pm - 9:00 pm	Dinner
Wednesday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Hormonal Signaling, Reproductive Cancers and Aging Discussion Leader: Francesca Duncan (Northwestern University, United States)
9:00 am - 9:10 am	Introduction by Discussion Leader
9:10 am - 9:35 am	Francesco DeMayo (National Institute of Environmental Health Sciences, NIH, United States) "The Role of Progesterone Receptor Isoforms in Uterine Function"
9:35 am - 9:45 am	Discussion
9:45 am - 10:10 am	Kathryn Grive (Women & Infants Hospital of RI/Brown University, United States) "Essential Roles for Ubiquitin C-Terminal Hydrolase L1 (UCHL1) Function in Mammalian Oocyte Proteostasis and Ovarian Function"
10:10 am - 10:20 am	Discussion
10:20 am - 10:30 am	Short Talk Selected from Poster Abstracts
10:30 am - 10:35 am	Discussion
10:35 am - 11:05 am	Coffee Break
11:05 am - 11:30 am	David Pepin (Massachusetts General Hospital, Harvard Medical School, United States) "Mechanisms of Action of AMH in the Ovary and Its Application to Contraception"
11:30 am - 11:40 am	Discussion
11:40 am - 11:50 am	Short Talk Selected from Poster Abstracts
11:50 am - 11:55 am	Discussion
11:55 am - 12:20 pm	Kara McKinley (Harvard University and Howard Hughes Medical Institute, United States) "Regeneration in the Uterus"
12:20 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:30 pm	Free Time
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 8:00 pm	Fetal-Maternal Interactions on Pregnancy Outcomes Discussion Leader: Gregory Johnson (Texas A&M University, United States)
6:00 pm - 6:10 pm	Introduction by Discussion Leader
6:10 pm - 6:35 pm	Samuel Antwi Oppong (University OF Ghana Medical School, Ghana) "Transitioning from Single to Multi-disciplinary Care for Pregnant Women with Sickle Cell Disease in Ghana: Impact on Maternal Mortality Rate"
6:35 pm - 6:45 pm	Discussion
6:45 pm - 7:10 pm	Rafael Domingues (The Ohio State University, United States) "Impacts of Antidepressants on Pregnancy Outcomes: Modulation of Placental Perfusion and Function"
7:10 pm - 7:20 pm	Discussion
7:20 pm - 7:45 pm	M.Sofia Ortega (University of Wisconsin-Madison, United States) "Paternal Regulation of the Preimplantation Embryo"
7:45 pm - 7:55 pm	Discussion
7:55 pm - 8:00 pm	General Discussion
8:00 pm - 9:00 pm	Dinner
Thursday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Business Meeting Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm	Defense Mechanisms in Healthy Reproductive Tissues Discussion Leader: Chris Geyer (East Carolina University, United States)
9:00 am - 9:10 am	Introduction by Discussion Leader
9:10 am - 9:35 am	Tony De Falco (Cincinnati Children's Hospital Medical Center, United States) "Sex-Specific Macrophage Origins and Functions in Gonadal Development and Gametogenesis"
9:35 am - 9:45 am	Discussion
9:45 am - 9:55 am	Short Talk Selected from Poster Abstracts
9:55 am - 10:00 am	Discussion
10:00 am - 10:10 am	Short Talk Selected from Poster Abstracts
10:10 am - 10:15 am	Discussion
10:15 am - 10:45 am	Coffee Break
10:45 am - 11:10 am	Soo Hyun Ahn (Michigan State University, United States) "When Tolerance Fails: Trace Metal Imbalance and Epididymal Fibrosis Contribute to Male Infertility"
11:10 am - 11:20 am	Discussion
11:20 am - 11:30 am	Short Talk Selected from Poster Abstracts
11:30 am - 11:35 am	Discussion
11:35 am - 11:45 am	Short Talk Selected from Poster Abstracts
11:45 am - 11:50 am	Discussion
11:50 am - 12:15 pm	Tzu-Wen Cross (Purdue University, United States) "From Gut to Gonads: The Interactions Between Microbiome and Sex Hormones"
12:15 pm - 12:25 pm	Discussion
12:25 pm - 12:30 pm	General Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:30 pm	Free Time
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 8:00 pm	Blazing New Paths from Essential Foundations in Reproductive Sciences Discussion Leaders: James Turner (The Francis Crick Institute, United Kingdom) and Julie Kim (Northwestern University, United States)
6:00 pm - 6:10 pm	Introduction by Discussion Leader
6:10 pm - 6:50 pm	Teresa Woodruff (Michigan State University, United States) "Engineering Reproduction"
6:50 pm - 7:00 pm	Discussion
7:00 pm - 7:40 pm	Anne Ferguson-Smith (University of Cambridge, United Kingdom) "The Genetics of Epigenetic Variation"
7:40 pm - 7:50 pm	Discussion
7:50 pm - 8:00 pm	Closing Remarks
8:00 pm - 9:00 pm	Dinner
Friday
7:30 am - 8:30 am	Breakfast
9:00 am	Departure

Contributors

Northwestern University

Research reported in this publication was supported by the Eunice Kennedy Shriver National Institute Of Child Health & Human Development of the National Institutes of Health under Award Number R13HD115381. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

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Conference History Mammalian Reproduction (GRS) Contribute Financially to This Conference

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Poster Information

Poster sessions are an integral part of the our conferences, and offer all conferees an opportunity to discuss their research.

Preparing your GRC poster

Diversity Funding

Financial assistance is available for qualified applicants through the GRC Carl Storm Underrepresented Minority Fellowship Program. This program provides a grant to underrepresented minority graduate students, postdocs, faculty and scientists to help fund their attendance at their first GRC meeting. Learn more.

Registration Fees

Conferee Single Room:

$1,605.00

Conferee Shared Room:

$1,350.00

Conferee Off-Site:

$1,085.00

Guest Single Room:

$1,415.00

Guest Shared Room:

$1,160.00

Guest Off-Site:

$895.00

Child 4-12 yrs Shared Room:

$581.00

Child 4-12 yrs Off-Site:

$448.00

Child Under 4 yrs Shared Room:

Free

Child Under 4 yrs Off-Site:

Free

Additional Fee Info

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