1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Lessons for the Future of Academic Breast Cancer Research from a Productive Past
Mike Oliphant (Harvard Medical School, United States)
3:45 pm - 4:25 pm
Heide Ford (University of Colorado Anschutz Medical Campus, United States) "34 Years in Academic Breast Cancer Research: Can We Do Everything, Everywhere, All at Once?"
4:25 pm - 4:30 pm
4:30 pm - 6:00 pm
6:00 pm - 7:00 pm
7:30 pm - 9:30 pm
Emerging Technologies and Alternative Models to Interrogate Mammary Gland Biology and Disease
Krystopher Maingrette (Rutgers - The State School of New Jersey, United States)
7:30 pm - 7:50 pm
James Miller (Cornell University, United States) "A Novel Xenotransplantation Mouse Model to Study Mammary Gland Pathogenesis of Large Mammals"
7:50 pm - 8:00 pm
8:00 pm - 8:20 pm
Sounak Sahu (National Cancer Institute (NCI), NIH, United States) "Directed Self-Assembly of Mouse ES Cells into Mammary Organoids Reveals the Dichotomy Between Skin and Mammary Gland Development"
8:20 pm - 8:30 pm
8:30 pm - 8:40 pm
Amelia Hasenauer (ETH Zürich, Switzerland) "Engineering Mammary Tissue Using Volumetric Bioprinting and Decellularized Extracellular Matrix-Based Materials"
8:40 pm - 8:45 pm
8:45 pm - 8:55 pm
Ramsey Jenschke (Texas A&M University, United States) "Changes in Mitochondrial Respiratory Chain Super Complexes Across Functional Mammary Gland Development"
8:55 pm - 9:00 pm
9:00 pm - 9:10 pm
Shengsen Ding (BC Cancer, Canada) "Characterization of Normal Human Male Mammary Cells and Induction of Male Breast Tumour Formation"
9:10 pm - 9:15 pm
9:15 pm - 9:25 pm
Carson Broeker (Michigan State University, United States) "The MMTV-Myc Mouse Model Recapitulates Human Breast Cancer Heterogeneity"
9:25 pm - 9:30 pm
7:30 am - 8:30 am
9:00 am - 11:00 am
Environmental Impacts on the Developing and Neoplastic Mammary Gland
Ramiah Vickers (Texas A&M University, United States)
9:00 am - 9:20 am
Maryknoll Linscott (Pennsylvania State University College of Medicine, United States) "Carcinogen-Initiated Mammary Cancer: Progression of Genetically Distinct Premalignant Clones Upon MYC and PIK3CA Expression"
9:20 am - 9:30 am
9:30 am - 9:50 am
Jakub Sumbal (Institut Curie, France - Masaryk University Czechia, France) "Peri-TEB Myofibroblasts Instruct Mammary Branching Morphogenesis"
9:50 am - 10:00 am
10:00 am - 10:10 am
Brenna Walton (University of Wisconsin-Madison, United States) "Acrylamide Exposure Enhances Oxidative Stress Leading to DNA Damage in the Obese Mouse Mammary Gland"
10:10 am - 10:15 am
10:15 am - 10:25 am
Nicole Traugh (Tufts University, United States) "Studying Breast Epithelial-Immune Interactions in A Biomimetic Tissue Model"
10:25 am - 10:30 am
10:30 am - 10:40 am
Connor Hughes (University of Colorado AMC, United States) "Eya3 Expression in Triple Negative Breast Cancer Alters Tumor Cell Aggressiveness and The Tumor Immune Microenvironment by Promoting Activation of NF-kB Signaling"
10:40 am - 10:45 am
10:45 am - 10:55 am
Laura Kammel (NIEHS, United States) "Circadian Disruption Induces Breast Cancer-Permissive Estrogen Receptor Transcriptional Program in Hormone Sensitive Mammary Epithelium"
10:55 am - 11:00 am
11:00 am - 12:30 pm
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
1:30 pm - 2:30 pm
Mentorship Component: How the NCI Can Help Advance Your Training and Career
Abbey Williams (University of Wisconsin - Madison, United States)
1:30 pm - 2:15 pm
Erika Ginsburg (NCI Center for Cancer Training, United States) "National Cancer Institute (NCI) Training Opportunities"
2:15 pm - 2:30 pm
2:30 pm - 3:00 pm
Complete the GRS Evaluation Forms; Election of Future Chair(s)