The Gordon Research Seminar on Matrix
Metalloproteinases is a unique forum for graduate students, post-docs, and
other scientists with varying levels of experience and education to present and
exchange new data and cutting edge ideas. In an informal, confidential and
friendly setting young minds can interact and make invaluable collaborations
with experienced researchers from academia and industry alike.
The focus of this meeting is to highlight recent
developments in the field of metallo-protease biology with a focus on the ADAM,
ADAMTS and MMP enzyme families. The discussions will center on the role of
these enzymes in regulating the complex biological processes involved in
development, tissue homeostasis, immune system regulation and diseases such as auto-immune
conditions, cardiovascular and neurological disorders, infectious diseases, and
Proteases act in the context of complex cascades creating
a multifaceted universe of protein-protein interactions dynamic and modulated
in disease states. Whether your interest lies in substrate/inhibitor design,
cell signaling pathways or utilizing existing tools to study a biological
condition involving metallo-proteases, this Gordon Research Seminar series is the place
for you. You will gain insight into the role of proteases in various disease
states, new technology being developed to investigate and image these enzymes
and leveraging this knowledge for drug discovery. We will take you back in time
to what we know about metallo-proteases to move forward and fill in the gaps of
what remains elusive. We will also discuss how to tackle the next generation
problems in the field of proteolysis to solve crucial biological problems in
The GRS attendees are also suggested to attend the
related GRC on Matrix Metalloproteinases (Chair, Howard C.
Crawford and Vice Chair, Rama Khokha). This meeting will indeed have a strong
representation from the next generation of scientists.
The GRS on Matrix Metalloproteinases will feature oral presentations, two poster sessions and a career
panel to advise on and discuss the range of career paths available to graduate
students and postdoctoral fellows.
Looking forward to seeing everyone is beautiful Maine.
Antoine Dufour (Chair) and Dina Hingorani (Associate