Conference Description
The Mechanisms of Epilepsy and Neuronal Synchronization GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.
Epilepsies are multifactorial spectrum of disorders which evolves over time. This GRC seeks to advance our understanding the diverse underlying processes that transform a seemingly normal brain to “dynamically” develop sudden unprovoked and recurrent episodes of abnormal hypersynchronous activity. Presentations will highlight current advances in studying the multiscale processes involved in epileptogenesis, from alterations in genetic and molecular profiles to changes in cellular, neurovascular, neuroimmune, microcircuit and network function which contribute to development of epilepsy and comorbid disorders that impact patient quality of life. Discussions will explore dynamic interactions between multiple complex systems including network physiology, cell and immune signaling, metabolic processes and transcriptomic changes at different stages of the disease, and how they can be targeted as biomarkers or therapeutically. This GRC will bring together scientists of diverse backgrounds at all career stages from within and outside the field for interactive and stimulating discussions to advance epilepsy research and ultimately impact patient care.
The topics, speakers, and discussion leaders for the conference sessions are displayed below. The conference chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by April 20, 2024. Please check back for updates.
Keynote Session: How Diverse Interacting Systems Shape Epilepsies
Discussion Leaders
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Christophe Bernard (Inserm, France)
Speakers
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Annamaria Vezzani (Mario Negri Institute for Pharmacological Research, Italy)
Dynamics of Synapses and Circuits in Epilepsies
Discussion Leaders
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Kevin Staley (Harvard Medical School, United States)
Speakers
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Michelle Antoine (National Institute on Alcohol Abuse and Alcoholism , United States)
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Marco de Curtis (Fondazione Istituto Neurologico Carlo Besta, Italy)
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Linda Overstreet-Wadiche (University of Alabama at Birmingham, United States)
Evolving Circuits During Development
Discussion Leaders
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Joaquin Lugo (Baylor University, United States)
Speakers
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Ranmal Samarasinghe (University of California, Los Angeles, United States)
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Angelique Bordey (Yale School of Medicine, United States)
The Interplay Between Inflammation, Microglia and Astrocytes
Discussion Leaders
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Karen Wilcox (University of Utah, United States)
Speakers
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Chris Dulla (Tufts University School of Medicine, United States)
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Long-Jun Wu (Mayo Clinic, United States)
Dynamics of the Cerebrovasculature and Associated Compartments
Discussion Leaders
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Daniela Kaufer (University of California, Berkeley, United States)
Speakers
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Gordon Teskey (University of Calgary, Canada)
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Dirk Dietrich (Universitätsklinik Bonn, Germany)
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Devin Binder (University of California, Riverside, United States)
Interacting Systems: Energetics, Metabolism and Oxidative Stress
Discussion Leaders
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Manisha Patel (University of Colorado, United States)
Speakers
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Mark Beenhakker (University of Virginia School of Medicine, United States)
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Avtar Roopra (University of Wisconsin at Madison, United States)
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Juan Pascual (Weill Cornell Medicine , United States)
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Kristina Simeone (Creighton University School of Medicine, United States)
Dynamic Omics
Discussion Leaders
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Ingrid Scheffer (University of Melbourne/Austin Health, Australia)
Speakers
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Jeffrey Noebels (Baylor College of Medicine , United States)
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Pablo Casillas-Espinosa (Monash University, Australia)
Computational Insights into Complex Systems
Discussion Leaders
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Sarah Muldoon (University of New York at Buffalo, United States)
Speakers
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Sridevi Sarma (Johns Hopkins University, United States)
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William Stacey (University of Michigan, United States)
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Yujiang Wang (Newcastle University, United Kingdom)
Beyond Seizures
Discussion Leaders
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Jaideep Kapur (University of Virginia, United States)
Speakers
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Jamie Maguire (Tufts University School of Medicine, United States)
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Jorge Palop (Gladstone Institutes / University of California, San Francisco, United States)
The GRC Power Hour™
Organizers
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Farah Lubin (University of Alabama at Birmingham, United States)