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Saturday
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| 2:00 pm - 5:00 pm |
Arrival and Check-in
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| 3:30 pm - 3:45 pm |
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
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| 3:45 pm - 4:30 pm |
Keynote Session: Translating New Technology in Epilepsy
Discussion Leader: Steve Danzer (Cincinnati Children's Hospital Medical Center, USA)
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| 3:45 pm - 4:20 pm |
Brian Litt (University of Pennsylvania, USA)
"Network Models to Guide Epilepsy Surgery"
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| 4:20 pm - 4:30 pm |
Discussion
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| 4:30 pm - 6:00 pm |
Poster Session
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| 6:00 pm - 7:00 pm |
Dinner
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| 7:30 pm - 9:30 pm |
Neural Circuits in Epilepsy
Discussion Leader: Karen Wilcox (University of Utah, USA)
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| 7:30 pm - 7:45 pm |
Julia Kahn (University of Pennsylvania, USA)
"Circuit-Based Therapies Rescue Cognitive Performance in a Temporal Lobe Epilepsy Mouse Model"
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| 7:45 pm - 7:55 pm |
Discussion
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| 7:55 pm - 8:10 pm |
Nicola Masala (Institute of Experimental Epileptology and Cognition Research, Germany)
"Altered CA1 Dendritic Integration in Chronically Acquired Epilepsy"
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| 8:10 pm - 8:20 pm |
Discussion
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| 8:20 pm - 8:35 pm |
Nadia Khan (University of Wisconsin-Madison, USA)
"Elucidating the Role of Enhancer of Zeste Homolog 2 (EZH2) in Epilepsy"
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| 8:35 pm - 8:45 pm |
Discussion
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| 8:45 pm - 9:00 pm |
Christopher Makinson (Stanford University, USA)
"Voltage-Gated Sodium Channel-Dependent Impairment of Action Potential Propagation Alter Cortical Network Function and Epilepsy Susceptibility"
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| 9:00 pm - 9:10 pm |
Discussion
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| 9:10 pm - 9:25 pm |
Julia Müller (Institute of Cellular Neurosciences, University of Bonn, Germany)
"Rescue of Astrocytic Gap Junction Coupling as a New Strategy to Prevent Epileptogenesis"
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| 9:25 pm - 9:30 pm |
Discussion
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Sunday
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| 7:30 am - 8:30 am |
Breakfast
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| 9:00 am - 11:00 am |
Translational Approaches in Epilepsy
Discussion Leader: Jenny Hsieh (The University of Texas at San Antonio, USA)
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| 9:00 am - 9:15 am |
Aswathy Ammothumkandy (University of Southern California, USA)
"Aberrant Adult Hippocampal Neurogenesis in Human Mesial Temporal Lobe Epilepsy"
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| 9:15 am - 9:25 am |
Discussion
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| 9:25 am - 9:40 am |
Trina Basu (University of Wisconsin-Madison, USA)
"Inhibiting Histone Deacetylase Activity Ameliorates Aberrant Synaptic Plasticity and Seizure Susceptibility in TSC2+/- Mice"
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| 9:40 am - 9:50 am |
Discussion
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| 9:50 am - 10:05 am |
Laura Bell (University of Utah, USA)
"Investigating the Role of mTOR in the Development of Focal Cortical Dysplasia and Drug-Resistant Epilepsy Using Patient Stem Cell-Derived Cortical Organoids"
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| 10:05 am - 10:15 am |
Discussion
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| 10:15 am - 10:30 am |
Wessel Woldman (University of Exeter, United Kingdom)
"Dynamic Network Properties Inferred from Resting-State EEG Can Determine Whether Seizures Appear Focal or Generalized"
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| 10:30 am - 10:40 am |
Discussion
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| 10:40 am - 10:55 am |
Jenny Koenig (Tufts University School of Medicine, USA)
"Glycolytic Inhibition with 2-Deoxyglucose Preserves Inhibitory Cortical Network Function Following Traumatic Brain Injury"
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| 10:55 am - 11:00 am |
Discussion
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| 11:00 am - 12:30 pm |
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
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| 12:30 pm - 1:30 pm |
Lunch
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| 1:30 pm - 2:30 pm |
Mentorship Component: Careers and Funding in Epilepsy Research
Discussion Leaders: Amanda Hernan (Larner College of Medicine, University of Vermont, USA) and Tristan Shuman (Icahn School of Medicine at Mount Sinai, USA)
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| 1:30 pm - 2:30 pm |
Panel Discussion
Careers and Funding in Epilepsy Research
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Steve Danzer (Cincinnati Children's Hospital Medical Center, USA)
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Jenny Hsieh (The University of Texas at San Antonio, USA)
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Brian Litt (University of Pennsylvania, USA)
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Karen Wilcox (University of Utah, USA)
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Penny Dacks (American Epilepsy Society, USA)
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Lauren Harte-Hargrove (Citizens United for Research in Epilepsy (CURE), USA)
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Vicky Whittemore (National Institute of Neurological Disorders and Stroke, NIH, USA)
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| 2:30 pm - 3:00 pm |
Evaluation Period
Fill in GRS Evaluation Forms
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| 3:00 pm |
Seminar Concludes
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