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Saturday
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| 2:00 pm - 5:00 pm |
Arrival and Check-in
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| 3:30 pm - 3:45 pm |
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
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| 3:45 pm - 4:30 pm |
Keynote Session: Mutation Strategies to Discover Mammalian Meiosis and Fertility Genes
Discussion Leader: Paula Cohen (Cornell University, USA)
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| 3:45 pm - 4:20 pm |
Philip Jordan (Johns Hopkins University Bloomberg School of Public Health, USA)
"Mutation Strategies to Discover Mammalian Meiosis Genes"
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| 4:20 pm - 4:30 pm |
Discussion
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| 4:30 pm - 6:00 pm |
Poster Session
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| 6:00 pm - 7:00 pm |
Dinner
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| 7:30 pm - 9:30 pm |
Initiation and Regulation of the Meiotic Program
Discussion Leader: Bernard de Massy (Institute of Human Genetics, France)
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| 7:30 pm - 7:45 pm |
Hui Tian (The Jackson Laboratory, USA)
"EWSR1 Regulates PRDM9-Dependent Histone 3 Methylation and Links Recombination Hotspots with the Chromosomal Axis"
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| 7:45 pm - 7:50 pm |
Discussion
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| 7:50 pm - 8:05 pm |
Baolu Shi (University of Pennsylvania, USA)
"Dual Functions of the ssDNA-Binding Protein RPA in Meiotic Recombination"
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| 8:05 pm - 8:10 pm |
Discussion
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| 8:10 pm - 8:25 pm |
Diedre Reitz (University of Chicago, USA)
"A Gain-of-Function Dmc1 Allele Reveals Distinct Mechanisms of Stimulation by Accessory Factors Mei5-Sae3 and Rad51"
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| 8:25 pm - 8:30 pm |
Discussion
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| 8:30 pm - 8:45 pm |
Jasvinder Ahuja (National Cancer Institute, NIH, USA)
"Divergent Mechanisms in Formation of Noncrossovers and Crossovers Revealed on Fine Structure Analysis of Meiotic Recombinants"
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| 8:45 pm - 8:50 pm |
Discussion
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| 8:50 pm - 9:05 pm |
Shaun Peterson (Memorial Sloan Kettering Cancer Center, USA)
"MSH2-Deficient Meiosis in F1 Hybrid Mice Reveals Meiotic Recombination Mechanism"
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| 9:05 pm - 9:10 pm |
Discussion
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| 9:10 pm - 9:25 pm |
Carolyn Milano (Cornell University, USA)
"Elucidating MutSγ Function During Mouse Meiosis Through the Generation of Point Mutant Mice"
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| 9:25 pm - 9:30 pm |
Discussion
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Sunday
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| 7:30 am - 8:30 am |
Breakfast
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| 9:00 am - 11:00 am |
Architecture and Dynamics of Meiotic Structures
Discussion Leader: Scott Keeney (Memorial Sloan Kettering Cancer Center, USA)
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| 9:00 am - 9:15 am |
Haitong Hou (National Cancer Institute, NIH, USA)
"When, How and Why Do Telomeres Control Meiotic Centromere Assembly"
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| 9:15 am - 9:20 am |
Discussion
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| 9:20 am - 9:35 am |
Luciana Previato de Almeida (Oklahoma Medical Research Foundation, USA)
"Mps2/Kash5 Connects the LINC Complex to Molecular Motors on the Cytoskeleton to Mediate Chromosome Movements in Budding Yeast and Mouse Meiosis"
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| 9:35 am - 9:40 am |
Discussion
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| 9:40 am - 9:55 am |
Chandni Ravindan (Wesleyan University, USA)
"A Constitutive 2:2 Complex Between Gmc2 and Ecm11 Within the Yeast Synaptonemal Complex"
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| 9:55 am - 10:00 am |
Discussion
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| 10:00 am - 10:15 am |
Cori Cahoon (University of Oregon, USA)
"Synaptonemal Complex Architecture Facilitates Chromosome-Specific Regulation of Recombination in Drosophila"
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| 10:15 am - 10:20 am |
Discussion
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| 10:20 am - 10:35 am |
Jason Sims (University of Vienna, Austria)
"Meiotic DNA Repair in the Nucleolus Employs a NHEJ Mechanism"
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| 10:35 am - 10:40 am |
Discussion
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| 10:40 am - 10:55 am |
Weronika Borek (University of Edinburgh, United Kingdom)
"The Ctf19/CCAN Kinetochore Complex Is Essential for Kinetochore-Microtubule Attachment in Meiosis I"
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| 10:55 am - 11:00 am |
Discussion
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| 11:00 am - 12:30 pm |
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
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| 12:30 pm - 1:30 pm |
Lunch
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| 1:30 pm - 2:30 pm |
Meiotic Errors and Checkpoint Signaling Mechanisms
Discussion Leader: Needhi Bhalla (University of California, Santa Cruz, USA)
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| 1:30 pm - 1:40 pm |
Zhouliang Yu (University of California, Berkeley, USA)
"The DNA Damage Response Regulates Chromosome Axis Assembly During C. elegans Meiosis"
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| 1:40 pm - 1:45 pm |
Discussion
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| 1:45 pm - 1:55 pm |
Viji Subramanian (New York University, USA)
"Ends: A Means to Establishing Chromosome Size Bias"
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| 1:55 pm - 2:00 pm |
Discussion
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| 2:00 pm - 2:10 pm |
Stephen Wellard (Johns Hopkins Bloomberg School of Public Health, USA)
"Regulation of Synaptonemal Complex Disassembly by Aurora Kinases During Mouse and Human Meiosis"
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| 2:10 pm - 2:15 pm |
Discussion
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| 2:15 pm - 2:25 pm |
Kostika Sofroni (University of Hamburg, Germany)
"Control of Meiotic Progression Through Cyclin-Dependent Kinase Complexes"
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| 2:25 pm - 2:30 pm |
Discussion
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| 2:30 pm - 3:00 pm |
Evaluation Period
Fill in GRS Evaluation Forms
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| 3:00 pm |
Seminar Concludes
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