Sunday
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4:00 pm - 8:00 pm |
Arrival and Check-in
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6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 7:40 pm |
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
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7:40 pm - 9:30 pm |
Clinical and Translational Metabolomics
Discussion Leader: Oliver Fiehn (University of California, Davis, USA)
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7:40 pm - 7:50 pm |
Opening Remarks
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7:50 pm - 8:30 pm |
David Wishart (University of Alberta, Canada)
"Moving Metabolomic Discoveries into the Clinic: Lessons from the Front Line"
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8:30 pm - 8:40 pm |
Discussion
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8:40 pm - 9:20 pm |
Eran Segal (Weizmann Institute of Science, Israel)
"Utilizing the Microbiome for Personalized Medicine"
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9:20 pm - 9:30 pm |
Discussion
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Monday
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7:30 am - 8:30 am |
Breakfast
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8:30 am - 9:00 am |
Group Photo
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9:00 am - 12:30 pm |
Advances in High-Throughput Metabolomics
Discussion Leader: David Wishart (University of Alberta, Canada)
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9:00 am - 9:35 am |
Oliver Fiehn (University of California, Davis, USA)
"Non-Invasive Sampling and Metabolome Analysis Across the Human Gut Intestinal Tract: Traveling from Stomach to Colon"
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9:35 am - 9:45 am |
Discussion
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9:45 am - 10:20 am |
Warwick Dunn (University of Birmingham, United Kingdom)
"The Role of UPLC-MS in High-Throughput Untargeted and Targeted Metabolomics"
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10:20 am - 10:30 am |
Discussion
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10:30 am - 11:00 am |
Coffee Break
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11:00 am - 11:35 am |
Thomas Hankemeier (Leiden University, The Netherlands)
"Novel Technologies for High Throughput and Miniaturized Metabolomics for Precision Medicine"
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11:35 am - 11:45 am |
Discussion
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11:45 am - 11:55 am |
Daniel Globisch (Uppsala University, Sweden)
"Discovery of Unknown Metabolic Interactions of Microbiota and Human Host: Combining Novel Metabolomics and Chemical Biology Methodologies"
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11:55 am - 12:00 pm |
Discussion
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12:00 pm - 12:10 pm |
Gang Xing (Pfizer Internal Medicine, USA)
"Development and Applications of Ion layer ERLIC Salt Protonation Double Ion Exchange (ESPDI) Liquid Chromatography in Metabolomics: A Case Study for Metabolome Digitization"
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12:10 pm - 12:15 pm |
Discussion
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12:15 pm - 12:25 pm |
Anupriya Tripathi (University of California, San Diego, USA)
"A Molecular Hierarchy for Improved Comparison of Untargeted Metabolomic Profiles"
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12:25 pm - 12:30 pm |
Discussion
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12:30 pm - 1:30 pm |
Lunch
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1:30 pm - 4:00 pm |
Free Time
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4:00 pm - 6:00 pm |
Poster Session
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6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 9:30 pm |
Impact of Gut Microbiome on Host Metabolism and Human Health
Discussion Leader: Ramnik Xavier (Massachusetts General Hospital, USA)
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7:30 pm - 8:10 pm |
Rob Knight (University of California, San Diego, USA)
"Gut Microbiome Metabolome Links in Human Disease"
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8:10 pm - 8:15 pm |
Discussion
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8:15 pm - 8:55 pm |
Sarkis Mazmanian (California Institute of Technology, USA)
"The Impact of Microbial Metabolism on Shaping Complex Animal Behavior"
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8:55 pm - 9:00 pm |
Discussion
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9:00 pm - 9:10 pm |
Partho Sen (Turku Centre for Biotechnology, Finland)
"Genome-Scale Metabolic Modelling of Gut Microbiota in Progression to Type 1 Diabetes"
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9:10 pm - 9:15 pm |
Discussion
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9:15 pm - 9:25 pm |
Almut Heinken (Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Luxembourg)
"Metabolic Modeling Reveals the Distinct Metabolic Potential in Gut Microbiomes of Inflammatory Bowel Disease Patients with Dysbiosis"
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9:25 pm - 9:30 pm |
Discussion
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Tuesday
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7:30 am - 8:30 am |
Breakfast
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9:00 am - 12:30 pm |
Lipidomics: Standardization, Quantification and Harmonization for Large Studies
Discussion Leader: Matej Oresic (University of Turku, Finland)
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9:00 am - 9:05 am |
Introduction by Discussion Leader
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9:05 am - 9:40 am |
Peter Meikle (Baker Heart and Diabetes Institute, Australia)
"Targeted Lipidomics by LC-MS/MS: Harmonisation Across Platforms, Laboratories and Studies"
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9:40 am - 9:50 am |
Discussion
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9:50 am - 10:25 am |
Xianlin Han (University of Texas Health Science Center at San Antonio, USA)
"Shotgun Lipidomics Sheds Light on Alzheimer's Disease: Implying the Importance of Standardization and Quantification in Lipidomics"
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10:25 am - 10:35 am |
Discussion
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10:35 am - 11:00 am |
Coffee Break
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11:00 am - 11:35 am |
Oswald Quehenberger (University California, San Diego, USA)
"Strategies for Identifying Quantitative Lipidomic Biomarkers for NASH and Other Inflammatory Diseases"
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11:35 am - 11:45 am |
Discussion
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11:45 am - 11:55 am |
Alan Bridge (SIB Swiss Institute of Bioinformatics, Switzerland)
"Enhanced Knowledge Resources for Metabolomics"
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11:55 am - 12:00 pm |
Discussion
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12:00 pm - 12:10 pm |
Federico Torta (National University of Singapore, Singapore)
"Defining Boundaries of Lipidomic Variations in Healthy Human Cohor"
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12:10 pm - 12:15 pm |
Discussion
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12:15 pm - 12:25 pm |
John Bowden (University of Florida, USA)
"The Next Steps for Advancing Lipidomics"
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12:25 pm - 12:30 pm |
Discussion
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12:30 pm - 1:30 pm |
Lunch
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1:30 pm - 4:00 pm |
Free Time
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4:00 pm - 6:00 pm |
Poster Session
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6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 9:30 pm |
Metabolome Nutrition and Precision Health
Discussion Leader: Susan Sumner (University of North Carolina at Chapel Hill, USA)
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7:30 pm - 8:05 pm |
Lorraine Brennan (School of Agriculture and Food Science, University College Dublin, Ireland)
"Metabotyping for Precision Nutrition"
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8:05 pm - 8:15 pm |
Discussion
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8:15 pm - 8:50 pm |
Gabi Kastenmüller (Helmholtz Zentrum München, Germany)
"Metabolites, Metabolism and Time"
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8:50 pm - 9:00 pm |
Discussion
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9:00 pm - 9:10 pm |
Jingyuan Fu (University Medical Center Groningen, The Netherlands)
"Diet-Host-Microbe Interaction Underlies Inter-Individual Variation in Human Metabolome"
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9:10 pm - 9:15 pm |
Discussion
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9:15 pm - 9:25 pm |
Brittany Lee-McMullen (Stanford University, USA)
"Physiological Effects of Prebiotic Fiber Supplementation on the Gut Microbiome and Human Host Serum"
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9:25 pm - 9:30 pm |
Discussion
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Wednesday
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7:30 am - 8:30 am |
Breakfast
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9:00 am - 12:30 pm |
Interactions Between the Metabolome, Exposome and Human Disease
Discussion Leader: Marc-Emmanuel Dumas (Imperial College London, United Kingdom)
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9:00 am - 9:40 am |
Ramnik Xavier (Massachusetts General Hospital, USA)
"Composition and Temporal Changes in the Gut Microbiome in Health and Disease"
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9:40 am - 9:50 am |
Discussion
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9:50 am - 10:25 am |
Susan Sumner (University of North Carolina at Chapel Hill, USA)
"The Exposome, Metabolome and Precision Nutrition"
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10:25 am - 10:35 am |
Discussion
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10:35 am - 11:00 am |
Coffee Break
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11:00 am - 11:35 am |
Tuulia Hyötyläinen (Örebro University, Sweden)
"Characterization of the Effect of Early-Life Environmental Exposure on Human Metabolome and Health"
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11:35 am - 11:45 am |
Discussion
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11:45 am - 11:55 am |
Lida Chatzi (University of Southern California, USA)
"The Early Life Exposome and Child Lipid Profile"
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11:55 am - 12:00 pm |
Discussion
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12:00 pm - 12:10 pm |
Lauren Petrick (Icahn School of Medicine at Mount Sinai, USA)
"Metabolomics-Based Evidence of the Etiologic Role of Early Life Nutrition in Pediatric Acute Lymphoblastic Leukemia (ALL)"
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12:10 pm - 12:15 pm |
Discussion
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12:15 pm - 12:25 pm |
Noam Bar (Weizmann Institute of Science, Israel)
"The Role of Diet, Lifestyle and Gut Microbiota in Shaping the Human Serum Metabolome"
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12:25 pm - 12:30 pm |
Discussion
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12:30 pm - 1:30 pm |
Lunch
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1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:00 pm - 7:30 pm |
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
|
7:30 pm - 9:30 pm |
Applications of Stable Isotope Resolved Metabolomics in Clinical and Preclinical Studies
Discussion Leader: Richard Higashi (University of Kentucky, USA)
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7:30 pm - 8:05 pm |
Teresa Fan (University of Kentucky, USA)
"Exploring Human Tumor and Immune Metabolism In Situ and in Preclinical Models Using Multiplexed Stable Isotope Resolved Metabolomics (mSIRM)"
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8:05 pm - 8:15 pm |
Discussion
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8:15 pm - 8:50 pm |
Ralph DeBerardinis (University of Texas Southwestern Medical Center, USA)
"Metabolic Outliers in Cancer and Other Human Diseases"
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8:50 pm - 9:00 pm |
Discussion
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9:00 pm - 9:10 pm |
Nicholas Lesner (University of Texas Southwestern Medical Center, USA)
"xCT Promotes Transsulfuration and Glucose Metabolism in Mitochondrial Dysfunction"
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9:10 pm - 9:15 pm |
Discussion
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9:15 pm - 9:25 pm |
Kalpana Ghoshal (The Ohio State University, USA)
"Regulation of Glutamine Metabolism by miR-122"
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9:25 pm - 9:30 pm |
Discussion
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Thursday
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7:30 am - 8:30 am |
Breakfast
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9:00 am - 12:30 pm |
The Metabolome as a Phenotypic Readout of the Genome
Discussion Leader: Gabi Kastenmüller (Helmholtz Zentrum München, Germany)
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9:00 am - 9:35 am |
Karsten Suhre (Weill Cornell Medicine-Qatar, Qatar)
"Lessons Learned from Connecting the Metabolome to the Genome and Proteome"
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9:35 am - 9:45 am |
Discussion
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9:45 am - 10:20 am |
Ines Thiele (Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Luxembourg)
"Exploring Host-Microbiome Co-Metabolism Through Metabolic Modeling"
|
10:20 am - 10:30 am |
Discussion
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10:30 am - 11:00 am |
Coffee Break
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11:00 am - 11:35 am |
Jonas Zierer (Weill Cornell Medicine, USA)
"The Fecal Metabolome as a Functional Readout of the Gut Microbiome"
|
11:35 am - 11:45 am |
Discussion
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11:45 am - 11:55 am |
Priyanka Baloni (Institute for Systems Biology, USA)
"Profiling Bile Acids to Understand Their Metabolic Role in Alzheimer's Disease"
|
11:55 am - 12:00 pm |
Discussion
|
12:00 pm - 12:30 pm |
Poster Previews
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 9:30 pm |
Metabolomics in Precision Medicine
Discussion Leader: Thomas Hankemeier (Leiden University, The Netherlands)
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7:30 pm - 8:10 pm |
Marc-Emmanuel Dumas (Imperial College London, United Kingdom)
"Integrative Phenomics for Precision Medicine and Biological Mechanisms"
|
8:10 pm - 8:20 pm |
Discussion
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8:20 pm - 8:55 pm |
Matthias Arnold (Helmholtz Zentrum München, Germany)
"Integrative Metabolomics in Alzheimer's Disease: Enabling Precision Medicine by Disease Sub-Classification"
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8:55 pm - 9:05 pm |
Discussion
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9:05 pm - 9:15 pm |
Boryana Petrova (Whitehead Institute for Biomedical Research, MIT, USA)
"Activation of Artemisinin by Heme Is Required for Its Anti-Parasitic Effects"
|
9:15 pm - 9:20 pm |
Discussion
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9:20 pm - 9:30 pm |
General Discussion
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Friday
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7:30 am - 8:30 am |
Breakfast
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9:00 am |
Departure
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