Sunday
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2:00 pm - 9:00 pm |
Arrival and Check-in
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6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 7:40 pm |
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
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7:40 pm - 9:30 pm |
Keynote Session: Supramolecular Metal-Based Molecules for Biomedical Applications
Discussion Leader: Michael Hannon (University of Birmingham, United Kingdom)
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7:40 pm - 7:45 pm |
Introduction by Discussion Leader
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7:45 pm - 8:10 pm |
Makoto Fujita (University of Tokyo, Japan)
"Crystalline Sponge Method for Natural Product Study and Drug Discovery"
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8:10 pm - 8:20 pm |
Discussion
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8:20 pm - 8:45 pm |
Xiaoyuan Chen (NUS, Singapore)
"Metallacages as Cancer Theranostics"
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8:45 pm - 8:55 pm |
Discussion
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8:55 pm - 9:20 pm |
Wenbin Lin (University of Chicago, United States)
"Nanoscale Coordination Polymers for Cancer Therapy"
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9:20 pm - 9:30 pm |
Discussion
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Monday
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7:30 am - 8:30 am |
Breakfast
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9:00 am - 12:30 pm |
Clinical Advances for Metals in Medicine
Discussion Leader: Walter Berger (Medical University of Vienna, Austria)
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9:00 am - 9:10 am |
Introduction by Discussion Leader
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9:10 am - 9:35 am |
Sherri McFarland (The University of Texas at Arlington, United States)
"Clinical Update on TLD1433, a Metallodrug Photosensitizer for Treating Non-Muscle Invasive Bladder Cancer with Photodynamic Therapy"
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9:35 am - 9:45 am |
Discussion
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9:45 am - 10:10 am |
Thomas Meade (Northwestern University, United States)
"Real-Time Tracking of Gene Therapy with Bioactivated MR Contrast Probes"
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10:10 am - 10:20 am |
Discussion
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10:20 am - 10:50 am |
Coffee Break
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10:50 am - 11:15 am |
Linda Vahdat (Dartmouth Hitchcock Medical Center, United States)
"Copper Depletion as a Therapeutic Strategy in Breast Cancer"
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11:15 am - 11:25 am |
Discussion
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11:25 am - 11:45 am |
Jacek Capala (National Institutes of Health, National Cancer Institute, United States)
"NCI Support for Research Focused on Radiopharmaceutical Therapy of Cancer"
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11:45 am - 11:55 am |
Discussion
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11:55 am - 12:15 pm |
General Discussion
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12:15 pm - 12:30 pm |
Poster Previews
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12:30 pm - 1:30 pm |
Lunch
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1:30 pm - 4:00 pm |
Free Time
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3:00 pm - 4:00 pm |
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Maria Contel (Brooklyn College and CUNY, United States) and Jason Lewis (Memorial Sloan Kettering Cancer Center, United States)
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4:00 pm - 6:00 pm |
Poster Session
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6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 9:30 pm |
Catalysis in Cells
Discussion Leaders: Luca Salassa (Donostia International Physics Center, Spain) and Loi Do (University of Houston Chemistry Department, United States)
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7:30 pm - 7:40 pm |
Introduction by Discussion Leader
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7:40 pm - 8:05 pm |
José Luis Mascareñas (Universidade de Santiago de Compostela, Spain)
"Biocompatible Transformations Involving Organometallic Catalysis "
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8:05 pm - 8:15 pm |
Discussion
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8:15 pm - 8:40 pm |
Siavash Kurdistani (UCLA, United States)
"Mechanism of Copper Reduction by Histone H3"
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8:40 pm - 8:50 pm |
Discussion
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8:50 pm - 9:05 pm |
Stefano Fedeli (University of Massachusetts Amherst - Department of Chemistry, United States)
"Bioorthogonal Nanozymes for Localized Cancer Imaging and Therapy"
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9:05 pm - 9:10 pm |
Discussion
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9:10 pm - 9:20 pm |
Short Talk Selected from Poster Abstracts
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9:20 pm - 9:30 pm |
Discussion
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Tuesday
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7:30 am - 8:30 am |
Breakfast
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8:30 am - 9:00 am |
Group Photo
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9:00 am - 12:30 pm |
Novel Metallomics Methods and Tools
Discussion Leaders: Samuel Meier-Menches (University of Vienna, Austria) and Dinorah Gambino (Facultad de Química, Universidad de la República, Uruguay, Uruguay)
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9:00 am - 9:05 am |
Introduction by Discussion Leader
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9:05 am - 9:30 am |
Eric Gale (Harvard University, United States)
"Iron Complexes for Precision Magnetic Resonance Imaging of Reactive Oxygen Species"
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9:30 am - 9:40 am |
Discussion
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9:40 am - 10:05 am |
Alessandra Magistrato (Scuola Internazionale Superiore di Studi Avanzati (SISSA), Italy)
"Dissecting the Mechanisms of Metal-binding Biomolecules via Multiscale Simulations"
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10:05 am - 10:15 am |
Discussion
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10:15 am - 10:45 am |
Coffee Break
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10:45 am - 11:05 am |
Sarah Michel (University of Maryland, United States)
"How to Find a Needle in a Haystack: Tracking Iron Nanoparticles in Clinical Samples"
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11:05 am - 11:15 am |
Discussion
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11:15 am - 11:30 am |
Sharon Ruthstein (Bar Ilan University, Israel)
"Deciphering the Cellular Copper Trafficking Mechanism to Develop a New Generation of Copper-Based Biomarkers"
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11:30 am - 11:40 am |
Discussion
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11:40 am - 12:00 pm |
Valeria Culotta (Johns Hopkins University, United States)
"Metals and Reactive Oxygen Species: Tales of a Successful Fungal Pathogen"
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12:00 pm - 12:10 pm |
Discussion
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12:10 pm - 12:30 pm |
Poster Previews
|
12:30 pm - 1:30 pm |
Lunch
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1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 9:30 pm |
Late-Breaking Topics
Discussion Leaders: Carolyn Anderson (University of Missouri, United States) and Anne-Kathrin Duhme-Klair (University of York, United Kingdom)
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7:30 pm - 7:35 pm |
Introduction by Discussion Leader
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7:35 pm - 7:55 pm |
Camilla Abbehausen (University of Campinas, Brazil)
"Metal-Based Compounds for Targeted Chemotherapy Against Leishmaniasis"
|
7:55 pm - 8:05 pm |
Discussion
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8:05 pm - 8:25 pm |
Orazio Vittorio (Children's Cancer Institute, Lowy Cancer Research Centre, Australia)
"Dissecting the Role of Copper in Cancer Progression, Angiogenesis and Immune Evasion"
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8:25 pm - 8:35 pm |
Discussion
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8:35 pm - 8:55 pm |
Jessie Nedrow (University of Pittsburgh, United States)
"Preliminary Evaluation of Alpha-emitting Radioembolization in Animal Models of Hepatocellular Carcinoma"
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8:55 pm - 9:05 pm |
Discussion
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9:05 pm - 9:25 pm |
Short Talk Selected from Poster Abstracts
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9:25 pm - 9:30 pm |
Discussion
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Wednesday
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7:30 am - 8:30 am |
Breakfast
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9:00 am - 12:30 pm |
Novel Chelation Strategies and Applications for Radionuclides and Contrast Agents
Discussion Leader: Eric Gale (Harvard University, United States)
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9:00 am - 9:05 am |
Introduction by Discussion Leader
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9:05 am - 9:30 am |
Rebecca Abergel (University of California, Berkeley, United States)
"Targeted Radionuclide Therapy: The Promise of Short-Lived Alpha-Emitting Actinides"
|
9:30 am - 9:40 am |
Discussion
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9:40 am - 10:05 am |
Peter Caravan (Massachusetts General Hospital, Harvard University, United States)
"Molecular MR and PET Probes for Detecting and Staging Tissue Fibrosis and Measuring Treatment Response"
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10:05 am - 10:15 am |
Discussion
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10:15 am - 10:45 am |
Coffee Break
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10:45 am - 11:10 am |
Jason Lewis (Memorial Sloan Kettering Cancer Center, United States)
"Zirconium-89-based Biomolecular Imaging Agents"
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11:10 am - 11:20 am |
Discussion
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11:20 am - 11:45 am |
Darren Magda (Lumiphore, Inc., United States)
"Macrocyclic 1,2-HOPO Bifunctional Chelators for Commercial Time-Resolved Eu(III) Luminescence Assays and Radiopharmaceutical Applications"
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11:45 am - 11:55 am |
Discussion
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11:55 am - 12:20 pm |
Katherine Vallis (University of Oxford, United Kingdom)
"Radionuclides, Ruthenium and Radiosensitisation"
|
12:20 pm - 12:30 pm |
Discussion
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12:30 pm - 1:30 pm |
Lunch
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1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:00 pm - 7:30 pm |
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
|
7:30 pm - 9:30 pm |
Essential Metals in Disease Mechanisms
Discussion Leader: Katherine Franz (Duke University, United States)
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7:30 pm - 7:35 pm |
Introduction by Discussion Leader
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7:35 pm - 8:00 pm |
Donita Brady (University of Pennsylvania, United States)
"Copper Conducted Kinase Signal Transduction: A Novel Vulnerability in Cancer"
|
8:00 pm - 8:10 pm |
Discussion
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8:10 pm - 8:35 pm |
Martin Burke (University of Illinois at Urbana-Champaign, United States)
"Molecular Prosthetics for Missing Metal Transporters"
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8:35 pm - 8:45 pm |
Discussion
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8:45 pm - 9:10 pm |
Matteo Ceccarelli (University of Cagliari, Italy)
"Rationalizing the Transport of Trojan Horse Compounds for Crossing the Outer Membrane of Gram-Negative Bacteria"
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9:10 pm - 9:20 pm |
Discussion
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9:20 pm - 9:30 pm |
General Discussion
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Thursday
|
7:30 am - 8:30 am |
Breakfast
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9:00 am - 12:30 pm |
Stimuli-Responsive Materials for Therapy and Imaging
Discussion Leader: Justin Wilson (Cornell University, United States)
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9:00 am - 9:10 am |
Introduction by Discussion Leader
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9:10 am - 9:35 am |
Rachela Popovtzer (Bar-Ilan University, Israel)
"Seeing Is Believing: Tracking the Movement of Cells Within Our Body "
|
9:35 am - 9:45 am |
Discussion
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9:45 am - 10:10 am |
Anna Cristina Samia (Case Western Reserve University, United States)
"Hydrogel Nanocomposites Designed for the Treatment of Prosthetic Joint Infections"
|
10:10 am - 10:20 am |
Discussion
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10:20 am - 10:50 am |
Coffee Break
|
10:50 am - 11:15 am |
Janet Morrow (University at Buffalo, SUNY, United States)
"Metal Organic Polyhedra for Murine Tumor Imaging and Drug Delivery"
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11:15 am - 11:25 am |
Discussion
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11:25 am - 11:50 am |
Gilles Gasser (Chimie ParisTech, PSL University, CNRS, Institute of Chemistry for Life and Health Sciences, France)
"Towards Specific Delivery and Controlled Release of Metal Complexes in Tumours"
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11:50 am - 12:00 pm |
Discussion
|
12:00 pm - 12:20 pm |
Late-Breaking Topic
|
12:20 pm - 12:30 pm |
Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 9:30 pm |
Targeted Metal-Based Therapeutics
Discussion Leader: Thomas Meade (Northwestern University, United States)
|
7:30 pm - 7:40 pm |
Introduction by Discussion Leader
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7:40 pm - 8:05 pm |
Seth Cohen (UC San Diego, United States)
"Metallofragments as 3-Dimensional Scaffolds for Fragment-Based Antiviral Drug Discovery"
|
8:05 pm - 8:15 pm |
Discussion
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8:15 pm - 8:40 pm |
Maria Contel (Brooklyn College and CUNY, United States)
"Biodegradable Nanocarriers and Antibodies as Targeting Delivery Vehicles for Gold-based Anticancer Agents"
|
8:40 pm - 8:50 pm |
Discussion
|
8:50 pm - 9:05 pm |
Short Talk Selected from Poster Abstracts
|
9:05 pm - 9:10 pm |
Discussion
|
9:10 pm - 9:25 pm |
Short Talk Selected from Poster Abstracts
|
9:25 pm - 9:30 pm |
Discussion
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Friday
|
7:30 am - 8:30 am |
Breakfast
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9:00 am |
Departure
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