Increasing evidence indicates that mitochondria are multifaceted organelles central to cell fate and function in both normal physiology and disease development. Multidisciplinary approaches ranging from basic biochemistry, structural studies and genetics; to multiomics interrogation of the proteome, metabolome and genome continue to unearth diverse and novel aspects of mitochondrial function at rapid pace. Such endeavors have also led to the discovery of previously unappreciated regulatory functions of otherwise “classic” mitochondrial pathways. These discoveries have also provided new opportunities to revisit old biologic questions and dogma with new tools.
The 2021 Gordon Research Conference on Mitochondria in Health and Disease will feature a wide range of rapidly evolving areas of mitochondrial science from basic biologic mechanisms to complex physiology and pathophysiology. The conference program has an integrative focus on novel molecular, cellular and organismal aspects of mitochondrial metabolism, bioenergetics and redox regulation, genome integrity and editing, protein biogenesis and proteostasis, iron trafficking, mitochondria-based crosstalk mechanisms via carrier systems, as well as interorganellar communications. Invited speakers include established and emerging mitochondrial biologists whose cutting-edge research has had high impact in the fields of aging, cancer, diabetes and obesity, cardiovascular disease, neurodegeneration, and inborn errors of metabolism. Scientific sessions will also include short talks from poster abstracts. The collective breadth of expertise and research interests featured in the conference program will catalyze productive cross-disciplinary collaborations. This is further enhanced by the conference format, which promotes presentation of unpublished data and provides protected time for discussions during scientific sessions, as well as built-in opportunities for informal interactions in the afternoons and evenings. Junior scientists and trainees will have opportunities to present their research in poster sessions and short talks selected from abstracts and to benefit from informal mentoring opportunities.
The conference will consist of nine sessions, on the topics listed below. The conference chair is currently developing their preliminary program, which will include the names of the invited speakers and discussion leaders for each of these sessions. Please check back regularly for updates to this information.
- Mitochondrial Energy Metabolism and Redox Regulation
- Mitochondrial Genome Maintenance and Editing
- Mitochondrial Protein Biogenesis
- Interorganellar Crosstalk
- Iron Trafficking and Metabolism
- Mitochondrial Carrier Proteins and Transporters
- Mitochondria in Senescence and Aging
- Mitochondria and Metabolic Regulation