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Modulation of Neural Circuits and Behavior

Gordon Research Conference

Dynamic Neural Processing in Adaptive Behaviors Across Species

May 18 - 23, 2025

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GRC Education Requirements: Undergraduates or those who have not obtained a bachelor's degree in science/engineering (or acceptable equivalent) are not eligible to apply to attend Gordon Research Conferences or Seminars.

Chairs

and

Vice Chairs

and

Les Diablerets Conference Center

Eurotel Victoria

Les Diablerets, Vaud (fr), Switzerland

Venue and Travel Information

Application Information

The application deadline for this meeting was April 20, 2025. You may still submit an application, which may be considered by the conference chair if there is still room available.

Conference Description

The Modulation of Neural Circuits and Behavior GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

Neuromodulatory systems, encompassing catecholamine and neuropeptide signaling, facilitate dynamic and adaptive neuronal processing both locally and brainwide across various temporal scales. Although foundational discoveries were made decades ago, new methods for in vivo imaging, neuronal and neural circuit manipulation, quantification of behavior and computational modeling are revisiting and challenging the established paradigms of circuit and behavioral neuroscience. This conference will bring together experts and junior scientists from a broad range of disciplines to share novel insights and develop new hypotheses of how nervous systems enable the remarkable spectrum of individual and collective behaviors from nematodes to humans.

Related Meeting

This GRC will be held in conjunction with the "Modulation of Neural Circuits and Behavior" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Conference Program

Sunday
2:00 pm - 9:00 pm	Arrival and Check-in
6:00 pm - 7:00 pm	Dinner
7:30 pm - 7:40 pm	Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm	Neuromodulation of Social Behavior Discussion Leader:
7:40 pm - 8:20 pm	"To Care or Not To Care: Sex- and State-Dependent Modulation of Social Interactions"
8:20 pm - 8:30 pm	Discussion
8:30 pm - 8:50 pm	"Chemical Tools for Dissecting Neuropeptide Control of Social Behavior and Physiology"
8:50 pm - 9:00 pm	Discussion
9:00 pm - 9:20 pm	"Natural Variation in Oxytocin Receptor Signaling Causes Widespread Changes in Brain Transcription: A Link to Innate Immunity?"
9:20 pm - 9:30 pm	Discussion
Monday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Neural Plasticity in Motivated Behaviors Discussion Leader:
9:00 am - 9:20 am	"Anger Management: Long-Term Modulation of Aggression by Short-Term Interference with Hypothalamic Circuits Controlling Social Behavior"
9:20 am - 9:30 am	Discussion
9:30 am - 9:50 am	"Hypothalamic Regulation of Male Mating Behaviors in Mice"
9:50 am - 10:00 am	Discussion
10:00 am - 10:15 am	"Accumbal Calcium-Permeable AMPA Receptors Orchestrate Neuronal Ensembles Underlying Social Attachment"
10:15 am - 10:20 am	Discussion
10:20 am - 10:50 am	Coffee Break
10:50 am - 11:10 am	"Trajectories of Behavioural and Neural Activity Adaptations in Depression"
11:10 am - 11:20 am	Discussion
11:20 am - 11:40 am	"Spatially Resolved Single-Cell Genomics and Cell Atlases of the Brain"
11:40 am - 11:50 am	Discussion
11:50 am - 12:05 pm	"Hypothalamic Plasticity for Alloparenting in Male Mice"
12:05 pm - 12:10 pm	Discussion
12:10 pm - 12:25 pm	"Hormonal Modulation of the Neural Circuitry Driving Innate Behaviours"
12:25 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Group Photo / Lunch
1:30 pm - 4:30 pm	Free Time
3:00 pm - 4:00 pm	The GRC Power Hour™ The GRC Power Hour™ is designed to address the interests and needs of all scientists and the challenges they face in their careers. Specifically, the program promotes meaningful conversations amongst colleagues of all career stages about barriers to career advancement and strategies to support the professional growth of all members of the community. The GRC Power Hour™ is open to all conference participants. Organizer:
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 8:00 pm	Neuromodulation of Innate Behavior in Invertebrates Discussion Leader:
6:00 pm - 6:20 pm	"Neuromodulators that Control a Context-Dependent Action Choice During Aggressive Interaction"
6:20 pm - 6:30 pm	Discussion
6:30 pm - 6:50 pm	"Neuropeptide Regulation of Mosquito Host-Seeking and Blood Feeding Behaviors"
6:50 pm - 7:00 pm	Discussion
7:00 pm - 7:20 pm	"From Stimulus to Action: How the Brain Balances Reproductive and Survival Needs"
7:20 pm - 7:30 pm	Discussion
7:30 pm - 7:50 pm	"GPCR Voltage Dependence and the Prevention of Type I and Type II Errors in the Brain"
7:50 pm - 8:00 pm	Discussion
8:00 pm - 9:00 pm	Dinner
Tuesday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Neural Mechanisms of Social Communication Discussion Leader:
9:00 am - 9:20 am	"Love, Death, and Oxytocin: The Challenges of Mouse Maternity"
9:20 am - 9:30 am	Discussion
9:30 am - 9:50 am	"Coding Properties and Underlying Synaptic Connections of Insular - Amygdala Networks in Fear Learning"
9:50 am - 10:00 am	Discussion
10:00 am - 10:15 am	"Molecular and Neural Activity Signatures of Claustrum Neurons in Stress and Vigilance Behaviors"
10:15 am - 10:20 am	Discussion
10:20 am - 10:50 am	Coffee Break
10:50 am - 11:10 am	"Neural Computation Gives Rise to Geometrical Principles of Spatial Decision-Making"
11:10 am - 11:20 am	Discussion
11:20 am - 11:40 am	"Neural Codes for Space in Social Groups of Bats and in Bats Navigating Outdoors on a Remote Oceanic Island"
11:40 am - 11:50 am	Discussion
11:50 am - 12:05 pm	"Neuromodulatory Organization of Stochastic Behavioral Individuality Across Development"
12:05 pm - 12:10 pm	Discussion
12:10 pm - 12:25 pm	"Implications of Retrospective Causal Learning"
12:25 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:30 pm	Free Time
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 8:00 pm	Affective Behavior Modulation and Learning Discussion Leader:
6:00 pm - 6:20 pm	"High-Dimensional Integration of Neuromodulatory Signals"
6:20 pm - 6:30 pm	Discussion
6:30 pm - 6:50 pm	"Olfactory Tubercle Mediates Adaptive Social Behavior through Distinct Control of Threat Assessment and Memory Updating"
6:50 pm - 7:00 pm	Discussion
7:00 pm - 7:20 pm	"The Habenula-Interpeduncular Pathway as a Possible Regulator of Allostasis and Resilience"
7:20 pm - 7:30 pm	Discussion
7:30 pm - 7:50 pm	"Impaired Cortical Oxytocin Signaling Prevents Mice from Entering Stable Social Clique"
7:50 pm - 8:00 pm	Discussion
8:00 pm - 9:00 pm	Dinner
Wednesday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Behavioral and Neural Network Dynamics Discussion Leader:
9:00 am - 9:20 am	"Mechanisms of Memory Stabilization Over Long Time-Scales"
9:20 am - 9:30 am	Discussion
9:30 am - 9:50 am	"Top-Down Modulation Shapes Cortical Dynamics Timescales"
9:50 am - 10:00 am	Discussion
10:00 am - 10:15 am	"VTA Dopaminergic Neuronal Activity During NREM Sleep is Modulated by Learning and Necessary for Memory Consolidation"
10:15 am - 10:20 am	Discussion
10:20 am - 10:50 am	Coffee Break
10:50 am - 11:10 am	"Active Sensing Modulates Pheromone Perception and Behavior"
11:10 am - 11:20 am	Discussion
11:20 am - 11:40 am	"The Brain's Maps for Navigational Goals"
11:40 am - 11:50 am	Discussion
11:50 am - 12:05 pm	"A PVN-PFC Oxytocin Circuit Maintaining Other-Directed Consolation Behaviors in Mice"
12:05 pm - 12:10 pm	Discussion
12:10 pm - 12:25 pm	"Prevention of Compulsive Grooming in a Mouse Model of OCD Using Long Term Circuit Modulation with Engineered Gap Junctions"
12:25 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:30 pm	Free Time
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 8:00 pm	Principles Underlying Neural Circuit Operation Discussion Leader:
6:00 pm - 6:20 pm	"Zebrafish Neural Circuit Detecting Choice-Outcome Events for Adaptive Defensive Behavior"
6:20 pm - 6:30 pm	Discussion
6:30 pm - 6:50 pm	"Neural Networks for Navigation"
6:50 pm - 7:00 pm	Discussion
7:00 pm - 7:15 pm	"ATP-Mediated Control of Sleep/Wake States"
7:15 pm - 7:20 pm	Discussion
7:20 pm - 7:35 pm	"Adenosine Signaling in Glia Modulates Metabolic State-Dependent Behavior"
7:35 pm - 7:40 pm	Discussion
7:40 pm - 7:55 pm	"Combinatorial Dynamics of Multiple Neuromodulatory Systems Primes Brain State for Adaptive Behavioral Strategies"
7:55 pm - 8:00 pm	Discussion
8:00 pm - 9:00 pm	Dinner
Thursday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Business Meeting Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm	Novel Tools to Uncover Neuromodulation Discussion Leader:
9:00 am - 9:20 am	"Sensitive Genetically Engineered Light Sensors for Tracking a Broad-Spectrum of Physiological Neurotransmitter Signaling"
9:20 am - 9:30 am	Discussion
9:30 am - 9:50 am	"Molecular Ballet: Decoding Neuromodulator Signaling Dynamics"
9:50 am - 10:00 am	Discussion
10:00 am - 10:15 am	"Fast Multiplexed Magnetogenetics Technology for Non-Invasive Neuromodulation"
10:15 am - 10:20 am	Discussion
10:20 am - 10:50 am	Coffee Break
10:50 am - 11:10 am	"Targeted Circuit Modulation in the Primate Brain"
11:10 am - 11:20 am	Discussion
11:20 am - 11:40 am	"Concept Neurons in the Human Medial Temporal Lobe as Semantic Building Blocks of Episodic Memory"
11:40 am - 11:50 am	Discussion
11:50 am - 12:05 pm	"Cholinergic Modulation of Dopamine Release Drives Effortful Behavior"
12:05 pm - 12:10 pm	Discussion
12:10 pm - 12:25 pm	"Tracking the Neural and Cognitive Trajectory Across the Lifespan in Mouse and Marmoset"
12:25 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:30 pm	Free Time
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 8:00 pm	Systemic Neuromodulation: Brain-Body-Axis Discussion Leader:
6:00 pm - 6:20 pm	"The Many Roles of Dopamine – Identifying Subcircuits in the Dopaminergic System that Modulate Motivated Behaviour"
6:20 pm - 6:30 pm	Discussion
6:30 pm - 6:50 pm	"Mutants with Pleiotropic Behavior Defects Highlight a Quality Control Mechanism for Biogenesis of GPCRs"
6:50 pm - 7:00 pm	Discussion
7:00 pm - 7:20 pm	"Sleep Regulation by Neuropeptide Signaling in C. Elegans"
7:20 pm - 7:30 pm	Discussion
7:30 pm - 7:50 pm	"Circuits and Behavior in Addiction and Related Disorders"
7:50 pm - 8:00 pm	Discussion
8:00 pm - 9:00 pm	Dinner
Friday
7:30 am - 8:30 am	Breakfast
9:00 am	Departure

Contributors

Research reported in this publication was supported by the National Institute Of Neurological Disorders And Stroke of the National Institutes of Health under Award Number R13NS141630. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

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Poster Information

Poster sessions are an integral part of the our conferences, and offer all conferees an opportunity to discuss their research.

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Funding Opportunities

Financial assistance is available beginning in 2026 for qualified applicants through the Carl Storm Opportunity Fellowships program. Learn more.

Registration Fees

Conferee Single Room:

$1,840.00

Conferee Shared Room:

$1,585.00

Conferee Off-Site:

$1,360.00

Guest Single Room:

$1,650.00

Guest Shared Room:

$1,395.00

Guest Off-Site:

$1,170.00

Child 4-12 yrs Shared Room:

$698.00

Child 4-12 yrs Off-Site:

$585.00

Child Under 4 yrs Shared Room:

Free

Child Under 4 yrs Off-Site:

Free

Additional Fee Info

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