Saturday
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2:00 pm - 5:00 pm |
Arrival and Check-in
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3:30 pm - 3:45 pm |
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
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3:45 pm - 4:30 pm |
Keynote Session: Leveraging Structural Biology to Study Natural Product Biosynthesis
Discussion Leader: Chunyu Wu (University of Illinois at Urbana-Champaign, USA)
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3:45 pm - 4:20 pm |
Catherine Drennan (Massachusetts Institute of Technology, USA)
"Snapshots of Metalloenzymes Involved in Natural Product Biosynthesis"
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4:20 pm - 4:30 pm |
Discussion
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4:30 pm - 6:00 pm |
Poster Session
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6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 9:30 pm |
Exploiting Nature to Make Natural Product Derivatives / Preparation of Complex Bioactive Natural Products
Discussion Leaders: Christopher Schwalen (Novartis Institutes for BioMedical Research, USA) and Matthew Anketell (University of Cambridge, United Kingdom)
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7:30 pm - 7:45 pm |
Ankur Sarkar (University of Colorado Boulder, USA)
"Microbial Synthesis and Evolution of Pharmaceutical Leads"
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7:45 pm - 7:50 pm |
Discussion
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7:50 pm - 8:05 pm |
Audrey Ynigez-Gutierrez (Vanderbilt University, USA)
"New Methods for Biosynthetic Derivatization of Antimicrobial Orthosomycins to Engage a Unique Ribosomal Binding Site"
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8:05 pm - 8:10 pm |
Discussion
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8:10 pm - 8:25 pm |
Kelsey Morgan (Duke University, USA)
"Investigation of Lipid II-Binding Antimicrobial Peptides"
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8:25 pm - 8:30 pm |
Discussion
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8:30 pm - 8:45 pm |
Philipp Sondermann (ETH Zurich, Switzerland)
"Total Synthesis of Mytilipin B"
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8:45 pm - 8:50 pm |
Discussion
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8:50 pm - 9:05 pm |
Zhiyao Zhou (The University of Chicago, USA)
"Asymmetric Synthesis of Caged Indolenine Alkaloids, Strictamine and Arborisidine"
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9:05 pm - 9:10 pm |
Discussion
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9:10 pm - 9:25 pm |
Vignesh Palani (University of California, Berkeley, USA)
"Development of a Unified Strategy for the Synthesis of Delavatine A and Incarviatone A"
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9:25 pm - 9:30 pm |
Discussion
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Sunday
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7:30 am - 8:30 am |
Breakfast
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9:00 am - 11:00 am |
Synthetic Efficiency via Computation and Catalyst Design / Tools for Characterizing Natural Products and Their Biosyntheses
Discussion Leaders: Masha Elkin (Yale University, USA) and Marius Grote (Ruhr-University Bochum, Germany)
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9:00 am - 9:15 am |
Kerry Betz (Stanford University, USA)
"From the Construction of Valuable Azacycles to New Catalyst Design: Using Catalyst-Controlled C-H Amination to Access Nitrogen-Containing Small Molecules"
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9:15 am - 9:20 am |
Discussion
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9:20 am - 9:35 am |
Daria Kim (Yale University, USA)
"Total Synthesis of Indoloditerpenoid Natural Products Enabled by Computational Augmentation of a Transform-Guided Retrosynthetic Strategy"
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9:35 am - 9:40 am |
Discussion
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9:40 am - 9:55 am |
Manish Walia (Temple University, USA)
"Synthesis of (-)-Melodinine K: A Case Study in Efficiency"
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9:55 am - 10:00 am |
Discussion
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10:00 am - 10:15 am |
Seven Nazipi (Aarhus University, Denmark)
"A Modified Isolation Chip for In Situ Cultivation and Isolation of Antimicrobial Drug-Producing Bacteria from Social Spider Nests"
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10:15 am - 10:20 am |
Discussion
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10:20 am - 10:35 am |
Seung Yeon Kim (Stanford University, USA)
"Partial Promiscuity of Dirigent Proteins and Their Application for Lignan Analog Synthesis"
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10:35 am - 10:40 am |
Discussion
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10:40 am - 10:55 am |
Tony Davis (University of California, San Diego, USA)
"Small Molecules to Probe Dynamic Protein-Protein Interactions in Fatty Acid and Polyketide Biosynthesis"
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10:55 am - 11:00 am |
Discussion
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11:00 am - 12:30 pm |
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
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12:30 pm - 1:30 pm |
Lunch
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1:30 pm - 2:30 pm |
Mentorship Component: Career Panel
Discussion Leader: Jeffrey Henry (The University of Notre Dame, USA)
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1:30 pm - 2:30 pm |
Panel Discussion
Careers in Natural Products
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Catherine Drennan (Massachusetts Institute of Technology, USA)
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David Gorin (Smith College, USA)
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Frank Petersen (Novartis Institutes for Biomedical Research, Switzerland)
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2:30 pm - 3:00 pm |
Evaluation Period
Fill in GRS Evaluation Forms
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3:00 pm |
Seminar Concludes
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