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Natural Products and Bioactive Compounds (GRS)

Gordon Research Seminar

Novel Approaches in Drug Discovery, Synthesis and Biosynthesis of Biological Relevant Natural Products

July 30 - 31, 2022
Chair
Proctor Academy
204 Main Street
Andover, New Hampshire, United States
 Venue and Travel Information

Conference Description

The Gordon Research Seminar is an exceptional meeting for early career researchers to come together, exchange new ideas, build a collaborative network and present unpublished cutting-edge data in the field of natural products.

This meeting will focus on all aspects of natural products highlighting the interdisciplinary nature of the field of natural products.

Abstracts are welcome in the fields of:

• Organic synthesis and methodology development

• Discovery, isolation and characterization of bioactive compounds

• Biosynthesis, genetic manipulation and synthetic biology

• Biological evaluation and mode action determination

The programme will include a keynote lecture and a session focused on career and professional development. Speakers for the general sessions will be chosen from submitted abstracts. Applicants not chosen for oral presentation are expected to present a poster.

Related Meeting

This GRS will be held in conjunction with the "Natural Products and Bioactive Compounds" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Marine Natural Products as a Source of Novel Chemistry
Discussion Leader:
3:45 pm - 4:15 pm
"Marine Natural Products Chemistry and the Shaping of a Career"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Natural Product Discovery, Biosynthesis and Bioactivity
Discussion Leader:
7:30 pm - 7:55 pm
"Systematic Discovery of Novel Classes of Plant Cyclic Peptides for Drug Development"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:25 pm
"Towards the Discovery of Non-Nucleoside Inhibitors of MraY Potent Against Mycobacterium tuberculosis"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:55 pm
"Paraburkholderia Isolates from Burned Soils Produce a Set of Rhamnolipid Methyl Esters, Unique Antimicrobial Surfactants"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:25 pm
"Potent In Vitro and In Vivo Anticancer Activities of Nicolaioidesin C, a Natural Product with the Ability to Eliminate Cancer Cells' Tolerance to Nutrition Starvation"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Modification and Total Synthesis of Complex Natural Products
Discussion Leader:
9:00 am - 9:20 am
"Employing Solid Phase Synthesis to Access Natural Product-Inspired Small Molecule Inhibitors of Phosphoglycosyl Transferases"
9:20 am - 9:25 am
Discussion
9:25 am - 9:45 am
"Progress Towards a Total Synthesis of Zetekitoxin AB"
9:45 am - 9:50 am
Discussion
9:50 am - 10:10 am
"The Design of a New Family of Chiral Rhodium Paddlewheel Complexes and their Application to Enantioselective Intermolecular Nitrogen Transfer Reactions"
10:10 am - 10:15 am
Discussion
10:15 am - 10:35 am
"Development of a Synthetic Platform For a Minimal Macrolide Pharmacophore"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
"A Pyridine Dearomatization Approach to the Matrine-type Lupin Alkaloids"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Breakout Groups: Careers in Natural Products
Discussion Leader:
1:30 pm - 2:20 pm
Panel Discussion
Careers in Natural Products
2:20 pm - 2:30 pm
General Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes

Contributors

National Institutes of Health - National Cancer Institute (NCI)
Enanta Pharmaceuticals, Inc.
Newcastle University - Faculty of Medical Sciences

Funding for this conference was made possible (in part) by 1R13CA264802-01 from the National Cancer Institute. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

Conference Links

Conference History Natural Products and Bioactive Compounds
Additional Fee Info

Natural Products and Bioactive Compounds
July 27 - August 1, 2025


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