Mechanisms of Notch Signaling in Health and Disease

The Notch Signaling in Development, Regeneration and Disease GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

The Notch signaling pathway is a central mediator of short-range, inter-cellular communication in multicellular organisms. Alterations of Notch activity underlie a growing list of developmental syndromes, adult onset diseases, and cancers, expanding the interest in this pathway well beyond the boundaries of basic developmental and cell biology and into the areas of stem cell biology, cancer biology and therapeutics. In addition to the premier talks mentioned above, a number of abstracts will be selected for short oral presentations. The inclusion and integration of a Gordon Research Seminar (GRS) exclusively for postdocs and graduate students prior to the GRC is a particular asset to draw new scientists into the field and encourage trainee participation. Most importantly, the combined GRC/GRS format excels in integrating students, postdocs and investigators wishing to enter a new field, such as the study of this important signaling pathway.