Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:15 pm - 4:00 pm
Structural Insights into Organellar Channels and Transporters
Discussion Leader: Daniel McKay (University of Heidelberg, Germany)
3:15 pm - 3:20 pm
Introduction by Discussion Leader
3:20 pm - 3:35 pm
Lynette Nel (Aarhus University, Denmark)
"Sterol Homeostasis in Vacuoles of Saccharomyces Cerevisiae Mediated by Niemann-Pick Type C Related Protein 1"
3:35 pm - 3:40 pm
Discussion
3:40 pm - 3:55 pm
Marton Liziczai (University of Zürich, Switzerland)
"Cryo-EM Structures and Mechanism of the Human Iron Importers"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Emerging Technologies and Exploration of the Function and Structure of Channels and Transporters
Discussion Leader: VERONICA LOYO CELIS (Ohio State University, United States)
5:30 pm - 5:35 pm
Introduction by Discussion Leader
5:35 pm - 5:55 pm
Shouguang Huang (University of Wuerzburg, Germany)
"A Light-Gated ChannelRhodopsin Powers Proton-Induced Calcium Release"
5:55 pm - 6:00 pm
Discussion
6:00 pm - 6:20 pm
Francesca Corti (Università degli Studi di Padova, Italy)
"The Role of Chloroplast Calcium Channel cMCU in Plant Stress Responses: Effects and Consequences of Chloroplast Calcium Handling under Drought"
6:20 pm - 6:25 pm
Discussion
6:25 pm - 6:45 pm
Dawid Jaslan (Ludwig-Maximilians-Universität München, Germany)
"Positive and negative regulators of TPC activity"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
Shridhar Sanghvi (The Ohio State University, United States)
"An Exosomal Large Conductance Calcium-Activated Potassium Channel Regulates its Cargo and Function"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:30 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Translational Insights into Organellar Channels and Transporters
Discussion Leader: Océane Guelle (Université Paris Cité, France)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
Reem Ali (Dr, Qatar)
"Dysregulation of the Glucose Transporter GLUT3 caused Hypersensitivity to Arsenite in PDRX1 Null Cells"
9:25 am - 9:30 am
Discussion
9:30 am - 9:50 am
Svenja Keller (Institute of Physiology, University of Zurich, Switzerland)
"Lysosomal Cystine Export Regulates mTORC1 Signaling to Guide Kidney Epithelial Cell Fate Specialization"
9:50 am - 9:55 am
Discussion
9:55 am - 10:15 am
Sushanth Adusumilli (Indian Institute of Technology Delhi, India)
"Analysis of Gene Expression Patterns and Association of Endo-Lysosomal Ion Channel TRPML3 with Important Autophagy Markers in the Context of Neurodegeneration"
10:15 am - 10:20 am
Discussion
10:20 am - 10:40 am
Haoxing Xu (Liangzhu laboratory & Zhejiang University Medical Center, China)
"Molecular Physiology of Organelles"
10:40 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Keynote Session: Endolysosomal cation channels as novel drug targets
Discussion Leader: Roni Levin Konigsberg (Stanford University, United States)
1:30 pm - 1:35 pm
Introduction by Discussion Leader
1:35 pm - 2:25 pm
Christian Grimm (Ludwig Maximilian University of Munich, Germany)
"Endolysosomal Cation Channels as Novel Drug Targets"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes