|1:30 pm - 4:30 pm||Arrival and Check-in|
|3:00 pm - 3:15 pm||Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair|
|3:15 pm - 4:00 pm||Aging Brain in Motion: An Imaging Strategy for Disease Diagnosis and Monitoring|
|Discussion Leader: Enrique Cadenas (University of Southern California, USA)|
|3:15 pm - 3:50 pm||Agneta Nordberg (Karolinska Institute, Sweden)
"Dynamic changes in PET amyloid and FDG imaging at different stages of Alzheimer's disease"
|3:50 pm - 4:00 pm||Discussion|
|4:00 pm - 5:30 pm||Poster Session I|
|5:30 pm - 7:30 pm||Common Mechanisms Underlying Brain Aging and Neurodegeneration|
|Discussion Leader: Roberta Diaz Brinton (University of Southern California, USA) |
|5:30 pm - 5:50 pm||Ana Ledo (Universidade de Coimbra, Portugal)
"Oxygen and nitric oxide concentration profiles linked to NMDA receptor activity in the hippocampus of a model of Alzheimer's disease"
|5:50 pm - 5:55 pm||Discussion|
|5:55 pm - 6:15 pm||Dimitrije Krstic (University of Zurich)
"Degenerating neurites as cause of Aß accumulation and amyloid plaque formation"
|6:15 pm - 6:20 pm||Discussion|
|6:20 pm - 6:40 pm||Gabriella Leonarduzzi (University of Turin, Italy)
"Interaction between lipid oxidation products and amyloid-β in amplifying neuronal damage in Alzheimer's disease"
|6:40 pm - 6:45 pm||Discussion|
|6:45 pm - 7:05 pm||Lauren Klosinski (University of Southern California, USA)
"Mechanistic link between mitochondrial dysfunction and white matter degeneration in the normal mammalian aging female brain: Proof of concept"
|7:05 pm - 7:10 pm||Discussion|
|7:10 pm - 7:25 pm||Arvind Goswami (Indian Institute of Science, India)
"Understanding the contribution of variants of mtHsp70 leading to mitochondrial dysfunction in Parkinson's disease"
|7:25 pm - 7:30 pm||Discussion|
|7:30 am - 8:30 am||Breakfast|
|9:00 am - 11:00 am||Prevention and Treatment for Brain Aging and Neurodegeneration: Translational Approaches|
|Discussion Leader: Agneta Nordberg (Karolinska Institute, Sweden|
|9:00 am - 9:20 am||Tianyi Jiang (University of Southern California)
"Lipoic Acid Restores Age-Associated Impairment of Brain Energy Metabolism"
|9:20 am - 9:25 am||Discussion|
|9:25 am - 9:45 am||Harsh Sancheti (University of Southern California)
"Lipoic Acid as a Therapeutic/Nutraceutical Agent in Alzheimer's Disease"
|9:45 am - 9:50 am||Discussion|
|9:50 am - 10:10 am||Natalie Noe (Institute for Genetics, Germany)
"Bezafibrate improves mitochondrial function in the CNS of a mouse model of mitochondrial encephalopathy"
|10:10 am - 10:15 am||Discussion|
|10:15 am - 10:35 am||Jamaica Rettberg (University of Southern California, USA)
"Development of metabolic and physiological biomarker profiles for early detection of women at risk for Alzheimer's disease"
|10:35 am - 10:40 am||Discussion|
|10:40 am - 10:55 am||Catia Lourenco (Universidade de Coimbra, Portugal) |
"Neuronal-nitric oxide dynamics and coupled neurovascular coupling in Alzheimer Disease and Aging"
|10:55 am - 11:00 am||Discussion|
|11:00 am - 12:30 pm||Poster Session II|
|Coffee will be served in the poster area from 11:00 am - 11:30 am|
|1:30 pm - 2:30 pm||Career Development|
|Discussion Leaders: Jia Yao (University of Southern California, USA) and Fei Yin (University of Southern California, USA)|
|1:30 pm - 2:15 pm||Ladora Thompson (University of Minnesota, USA)
"Negotiating The First Academic Position & Identifying Career Development Applications for Success"
|2:15 pm - 2:30 pm||Discussion|
|2:30 pm - 3:00 pm||Evaluation Period|
|Fill out GRS Evaluation Forms|
|3:00 pm||Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm.|