Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Redox Signalling and Metabolism
Discussion Leaders: Roberto Di Maio (University of Pittsburgh, USA) and Chathurika Henpita (University of Minnesota, USA)
3:45 pm - 4:25 pm
Sruti Shiva (University of Pittsburgh, USA)
"Understanding the Interaction of Mitochondria with Nitrogen and Oxygen Radicals: A 'Complex' Story"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Redox Biology in Disease
Discussion Leader: Jennifer Pearson-Smith (University of Colorado Anschutz Medical Campus, USA)
7:30 pm - 7:45 pm
Simone Adinolfi (University of Eastern Finland, Finland)
"Differential Protein S-Glutathionylation of Metabolic Enzymes in NRF2 Overexpressing and Deficient Lung Cancer Cells"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Evan Elko (University of Vermont, USA)
"Linking Peroxiredoxin 4 and ER Oxidative Stress to Idiopathic Pulmonary Fibrosis"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:30 pm
Clara Troccoli (University of Miami, USA)
"Targeting a Novel Redox-Regulated Mechanism as a Therapeutic Vulnerability in Castration-Resistant Prostate Cancer"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:55 pm
Sanjukta Guha (L V Prasad Eye Institute, India)
"Role of SLC4A11 and NRF2 in Regulation of Antioxidant Signalling in Corneal Endothelial Dystrophy"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:20 pm
Nicolas Chamberlain (University of Vermont, USA)
"PDI Inhibition During Influenza Infection Alters Viral Protein Maturation"
9:20 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Implications of Oxygen Radicals and the Use of Different Model Systems
Discussion Leaders: Allison Manuel (University of Vermont, USA), Stephenson Boakye Owusu (University of Paris-Saclay, France) and Jiaqi Wu (St. John's University, USA)
9:00 am - 9:15 am
LeeAnne Daley (St. John's University, USA)
"GM-1111 Restores Hyperoxia-Compromised Macrophage Function via Interruption of HMGB1-Mediated Signaling and Proinflammatory Response"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Elshaddai White (Clark Atlanta University, USA)
"Serum Deprivation Primes Cancer Cells to Adapt and Survive Oxidative Stress"
9:35 am - 9:45 am
Discussion
9:45 am - 10:00 am
Morgan Foret (McGill University, Canada)
"Quantifying and Visualizing Lipid Peroxyl Radicals Real-Time in Primary Neuronal Cultures"
10:00 am - 10:10 am
Discussion
10:10 am - 10:25 am
Sandeep Saxena (University of Kentucky, USA)
"Stress Resistance Mechanisms in Highly Regenerative Mammals"
10:25 am - 10:35 am
Discussion
10:35 am - 10:50 am
Ashwini Sri Hari (University of Colorado Anschutz Medical Campus, USA)
"Elevation of Cellular Glutathione Inhibits Neuronal Hyperexcitability In Vitro and In Vivo "
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Mentoring and Career Development
Discussion Leaders: Alex Gauthier (St. John's University, USA) and Yvonne Janssen-Heininger (Larner College of Medicine, University of Vermont, USA)
1:30 pm - 2:20 pm
Alicia Kowaltowski (Universidade de Sao Paulo, Brazil)
"What I Discovered While Becoming an Ever More Experienced Scientist"
2:20 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes