Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Signals and Forces in Leukocyte Activation
Discussion Leader: William Nauseef (University of Iowa, United States)
7:40 pm - 8:00 pm
Introduction by Discussion Leader
8:00 pm - 8:30 pm
Klaus Ley (Augusta University, United States)
"Beta2 Integrin Activation"
8:30 pm - 8:45 pm
Discussion
8:45 pm - 9:15 pm
Ana-Maria Lennon-Dumenil (Institut Curie, France)
"The Response of Phagocytes to Cell Shape Changes"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Phagocyte Function, Immunity and Disease
Discussion Leader: Silvia Uriarte (University of Louisville, United States)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
Ivan Zanoni (Harvard Medical School - Boston Children's Hospital, United States)
"Metabolic Regulation of Macrophage Functions"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
Emanuela Bruscia (Yale University School of Medicine, United States)
"Pathological Lung Inflammation and Remodeling in Cystic Fibrosis: Are Macrophages the Culprit?"
9:55 am - 10:05 am
Discussion
10:05 am - 10:15 am
Short Talk Selected from Poster Abstracts
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
Short Talk Selected from Poster Abstracts
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:25 am
Markus Sperandio (Ludwig Maximilians University Munich, Germany, Germany)
"NLRP3 Inflammasome Activation in Neutrophils"
11:25 am - 11:35 am
Discussion
11:35 am - 11:55 am
Catherine 'Lynn' Hedrick (Augusta University, United States)
"Monocytes: Soldiers in Health and Disease"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:15 pm
Late-Breaking Topic
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Silvia Uriarte (University of Louisville, United States) and Mallary Greenlee-Wacker (Cal Poly SLO, United States)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Phagocytes in Inflammatory Disease
Discussion Leader: Florence Niedergang (Institut Cochin, France)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
Marco Antonio Cassatella (University of Verona, Italy, Italy)
"Understanding the Mechanisms Whereby Slan-Positive Monocytes Kill Cancer Cells During ADCC"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
Veronique Witko-Sarsat (INSERM U1016-Institut Cochin, France)
"The Proliferating Cell Nuclear Antigen (PCNA) as a Versatile Regulator of Neutrophil Activation in Inflammatory Diseases"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:55 pm
Late-Breaking Topic
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Short Talk Selected from Poster Abstracts
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Cellular Immunity, Autophagy and Cell Death
Discussion Leader: Gustavo Menezes (Federal University of Minas Gerais (UFMG), Brazil)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
Mordecahy Gerlic (Tel Aviv university, Israel)
"The Trojan Horse: Two T6SS Effectors Induce Pyroptosis Upon Phagocytosis"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
Sanja Arandjelovic (University of Virginia, United States)
"Regulation of Neutrophil-Mediated Inflammation by ELMO1"
9:55 am - 10:05 am
Discussion
10:05 am - 10:15 am
Short Talk Selected from Poster Abstracts
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
Short Talk Selected from Poster Abstracts
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:25 am
Carlos Rosales (Universidad Nacional Autónoma de México, Mexico)
"Specific Signaling by Fc Receptors in Human Neutrophils"
11:25 am - 11:35 am
Discussion
11:35 am - 11:55 am
Arturo Zychlinsky (Max Planck Institute for Infection Biology, Germany)
"Neutrophil Extracellular Traps"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:15 pm
Late-Breaking Topic
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Migration in Immunity and Inflammation
Discussion Leader: Daniel Irimia (Massachusetts General Hospital, Harvard Medical School, United States)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
Gustavo Menezes (Federal University of Minas Gerais (UFMG), Brazil)
"A Developmental Approach on Liver Immune and Metabolic System Under the Eyes of High Dimensional Intravital Microscopy"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
Carole Parent (University of Michigan, United States)
"Dissecting the Mechanisms that Regulate Neutrophil Chemotaxis and NET Release"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:55 pm
Late-Breaking Topic
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Short Talk Selected from Poster Abstracts
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Mechanisms of Phagocytosis in Macrophages and Dendritic Cells
Discussion Leader: Mallary Greenlee-Wacker (Cal Poly SLO, United States)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
Julie Magarian Blander (Weill Cornell Medicine, United States)
"A Phagocytic Mode of Noncanonical NLRP3 Inflammasome Activation"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
Johnathan Canton (University of Calgary, Canada)
"Apolipoprotein Control of Antigen Cross-Presentation by Classical Dendritic Cells"
9:55 am - 10:05 am
Discussion
10:05 am - 10:15 am
Short Talk Selected from Poster Abstracts
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
Short Talk Selected from Poster Abstracts
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:25 am
Roberto Botelho (Ryerson University, Canada)
"Determinants of Phagocytic Appetite Exhaustion and Recovery"
11:25 am - 11:35 am
Discussion
11:35 am - 11:55 am
Sergio Grinstein (The Hospital for Sick Children, Canada)
"Quiescent Actin Dynamics Following Phagocytosis: Macrophages Hibernate After a Large Meal"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:15 pm
Late-Breaking Topic
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Microglia, Phagocytosis in the Central Nervous System
Discussion Leader: Ivan Zanoni (Harvard Medical School - Boston Children's Hospital, United States)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
Dorothy Schafer (University of Massachusetts Chan Medical School, United States)
"Phagocytosis Within Neural Circuits: A Synapse Makes for a Good Meal"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
Anna Victoria Molofsky (University of California, San Francisco, United States)
"Defining Novel Modes of Microglial Phagocytosis During Brain Development"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:55 pm
Late-Breaking Topic
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Short Talk Selected from Poster Abstracts
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Phagocytes in Host-Pathogen Interaction
Discussion Leader: Roberto Botelho (Ryerson University, Canada)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
Sunny Shin (University of Pennsylvania Perelman School of Medicine, United States)
"Alveolar Epithelium: Myeloid Cell Crosstalk in Anti-Bacterial Defense"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
Juhi Bagaitkar (The Ohio State University and Nationwide Children's Hospital, United States)
"Manipulating Efferocytosis: A New Role for P.gingivalis Proteases"
9:55 am - 10:05 am
Discussion
10:05 am - 10:15 am
Short Talk Selected from Poster Abstracts
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
Short Talk Selected from Poster Abstracts
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:25 am
Jorge Galan (Yale School of Medicine, United States)
"A Cell-Intrinsic Host Defense Pathway that Controls Salmonella Intracellular Replication"
11:25 am - 11:35 am
Discussion
11:35 am - 11:55 am
Keke Fairfax (University of Utah, United States)
"To Protect a Host: Unwinding the Mechanisms of Helminth Antigens in Reprogramming Host Myeloid Cells"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:15 pm
Late-Breaking Topic
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Phagocytes, Mucosal Immunity and the Microbiota
Discussion Leader: Sanja Arandjelovic (University of Virginia, United States)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
Gretchen Diehl (Memorial Sloan Kettering, United States)
"The Microbiota and Development of Intestinal Immunity"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
Niki Moutsopoulos (National Institute of Dental and Craniofacial Research, NIH, United States)
"Neutrophils at the Mucosal Interphase: Friend or Foe?"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:55 pm
Late-Breaking Topic
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Short Talk Selected from Poster Abstracts
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure