2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
New Methods and Models
Claudia Rival (University of Virginia, USA)
3:45 pm - 3:55 pm
Kiran Roberts (University of Bristol, United Kingdom) "
Ex Vivo Culture of Neutrophils as a Tool to Examine Neutrophil Cell Biology and Functionality"
3:55 pm - 4:00 pm
4:00 pm - 4:10 pm
Kathryn Wierenga (Michigan State University, USA) "Omega-3 Fatty Acid Suppression of Silica-Induced Inflammasome Activation in a Novel Alveolar Macrophage Model"
4:10 pm - 4:15 pm
4:15 pm - 4:25 pm
Julien Subburayalu (University of Cambridge, United Kingdom) "Killing Me Softly: An Unbiased Proteomic Approach to Identifying Novel 'Eat Me' Signatures on Apoptotic Neutrophils"
4:25 pm - 4:30 pm
4:30 pm - 6:00 pm
6:00 pm - 7:00 pm
7:30 pm - 9:30 pm
Pedro Marques (The Hospital for Sick Children, Canada)
7:30 pm - 7:40 pm
Paul Imbert (Peter Gilgan Centre for Research and Learning, SickKids, Canada) "The Role of the Macrophage Glycocalyx in Phagocytosis"
7:40 pm - 7:45 pm
7:45 pm - 7:55 pm
Catherine Buckley (University of Birmingham, United Kingdom / The Hospital for Sick Children, Canada) "Mechanisms of Na+ Trafficking in Macropinosomes and Lysosomes"
7:55 pm - 8:00 pm
8:00 pm - 8:10 pm
Anna D'Amico (Albany Medical College, USA) "PKC-E and Post-Golgi Trafficking During Phagocytosis"
8:10 pm - 8:15 pm
8:15 pm - 8:25 pm
Therese de Neergaard (Lund University, Sweden) "Interaction-Normalized Assessment of Phagocytosis Reveals Non-Linear Igg-Fc Receptor Engagement Dependency"
8:25 pm - 8:30 pm
8:30 pm - 8:40 pm
Saumil Sethna (University of Maryland School of Medicine, USA) "CIB2 Is Essential for Phagocytosis and Visual Function"
8:40 pm - 8:45 pm
8:45 pm - 8:55 pm
Viktória Szeifert (Semmelweis University, Hungary) "The Role of Calcium Signaling in Formation and Function of Neutrophilic Granulocyte Derived Extracellular Vesicles"
8:55 pm - 9:00 pm
9:00 pm - 9:10 pm
Ziv Roth (The Hospital for Sick Children, Canada) "Differential Effect of M-CSF vs. GM-CSF on Macrophage Polarization"
9:10 pm - 9:15 pm
9:15 pm - 9:25 pm
Michelle Sugimoto (Federal University of Minas Gerais, Brazil) "Plasminogen and the Plasminogen Receptor, Plg-R KT, Regulate Macrophage Phenotypic and Functional Changes"
9:25 pm - 9:30 pm
7:30 am - 8:30 am
9:00 am - 11:00 am
Gregory Olson (University of Washington, USA)
9:00 am - 9:10 am
Tobias Dallenga (Research Center Borstel, Germany) "Neutrophils as Targets for Host-Directed Therapy Against Tuberculosis"
9:10 am - 9:15 am
9:15 am - 9:25 am
Basel Abuaita (University of Michigan Medical School, USA) "Mitochondria-Derived Vesicles Deliver Antimicrobial Payload to Control Phagosomal Bacteria"
9:25 am - 9:30 am
9:30 am - 9:40 am
Rachel Kinsella (Washington University in St. Louis, USA) "Investigating the Mechanism by Which ATG5 Controls Inflammation During
Mycobacterium tuberculosis Infection"
9:40 am - 9:45 am
9:45 am - 9:55 am
William Pandori (University of California, Irvine, USA) "Regulation of IL-1β Production and Release During
Toxoplasma gondii Infection of Primary Human Monocytes"
9:55 am - 10:00 am
10:00 am - 10:10 am
Alissa Rothchild (Seattle Children's Research Institute, USA) "Alveolar Macrophages Up-Regulate a Non-Classical Innate Response to
Mycobacterium tuberculosis Infection In Vivo"
10:10 am - 10:15 am
10:15 am - 10:25 am
Annica Stull-Lane (University of California, Davis, USA) "NRAMP1/SLC11A1 Contributes to the Antimicrobial Response of Neutrophils"
10:25 am - 10:30 am
10:30 am - 10:40 am
Johannes Westman (The Hospital for Sick Children, Canada) "Regulation of Phagosomal Size and Integrity During Infection"
10:40 am - 10:45 am
10:45 am - 10:55 am
Glenn Walpole (The Hospital for Sick Children, Canada) "Inactivation of Rho Gtpases by
Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Modulates Phagosome Maturation"
10:55 am - 11:00 am
11:00 am - 12:30 pm
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
1:30 pm - 2:30 pm
Phagocytes in Disease
Fernando Montano Rendon (Hospital for Sick Children / University of Toronto, Canada)
1:30 pm - 1:40 pm
Sabine Arve (Lund University, Sweden) "Neutrophil Extracellular Traps Serve as Antigens for Antinuclear Antibodies in Juvenile Idiopathic Arthritis"
1:40 pm - 1:45 pm
1:45 pm - 1:55 pm
Mar Bosch Queralt (German Centre for Neurodegenerative Diseases, Germany) "Impaired Lipid Handling by Phagocytes Prevents Myelin Regeneration in the Central Nervous System"
1:55 pm - 2:00 pm
2:00 pm - 2:10 pm
Caterina Di Pietro (Yale University, USA) "Pharmocological Induction of the HO-1/CO Pathway in Macrophages Ameliorates Cystic Fibrosis Lung Hyper-Inflammation"
2:10 pm - 2:15 pm
2:15 pm - 2:25 pm
Hasan Oz (Yale School of Medicine, USA) "Dysregulated Dynamics of Monocyte-Derived Macrophages During Pulmonary Chronic Inflammation Contribute to CF Airway Remodeling"
2:25 pm - 2:30 pm
2:30 pm - 3:00 pm
Fill in GRS Evaluation Forms