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Saturday
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| 2:00 pm - 5:00 pm |
Arrival and Check-in
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| 3:30 pm - 3:45 pm |
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
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| 3:45 pm - 4:30 pm |
New Methods and Models
Discussion Leader: Claudia Rival (University of Virginia, USA)
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| 3:45 pm - 3:55 pm |
Ted Roberts (University of Bristol, United Kingdom)
"Ex Vivo Culture of Neutrophils as a Tool to Examine Neutrophil Cell Biology and Functionality"
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| 3:55 pm - 4:00 pm |
Discussion
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| 4:00 pm - 4:10 pm |
Kathryn Wierenga (Michigan State University, USA)
"Omega-3 Fatty Acid Suppression of Silica-Induced Inflammasome Activation in a Novel Alveolar Macrophage Model"
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| 4:10 pm - 4:15 pm |
Discussion
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| 4:15 pm - 4:25 pm |
Julien Subburayalu (University of Cambridge, United Kingdom)
"Killing Me Softly: An Unbiased Proteomic Approach to Identifying Novel 'Eat Me' Signatures on Apoptotic Neutrophils"
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| 4:25 pm - 4:30 pm |
Discussion
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| 4:30 pm - 6:00 pm |
Poster Session
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| 6:00 pm - 7:00 pm |
Dinner
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| 7:30 pm - 9:30 pm |
Phagocytosis
Discussion Leader: Pedro Marques (The Hospital for Sick Children, Canada)
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| 7:30 pm - 7:40 pm |
Paul Imbert (Peter Gilgan Centre for Research and Learning, SickKids, Canada)
"The Role of the Macrophage Glycocalyx in Phagocytosis"
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| 7:40 pm - 7:45 pm |
Discussion
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| 7:45 pm - 7:55 pm |
Catherine Buckley (University of Birmingham, United Kingdom / The Hospital for Sick Children, Canada)
"Mechanisms of Na+ Trafficking in Macropinosomes and Lysosomes"
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| 7:55 pm - 8:00 pm |
Discussion
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| 8:00 pm - 8:10 pm |
Anna D'Amico (Albany Medical College, USA)
"PKC-E and Post-Golgi Trafficking During Phagocytosis"
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| 8:10 pm - 8:15 pm |
Discussion
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| 8:15 pm - 8:25 pm |
Therese de Neergaard (Lund University, Sweden)
"Interaction-Normalized Assessment of Phagocytosis Reveals Non-Linear Igg-Fc Receptor Engagement Dependency"
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| 8:25 pm - 8:30 pm |
Discussion
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| 8:30 pm - 8:40 pm |
Saumil Sethna (University of Maryland School of Medicine, USA)
"CIB2 Is Essential for Phagocytosis and Visual Function"
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| 8:40 pm - 8:45 pm |
Discussion
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| 8:45 pm - 8:55 pm |
Viktória Szeifert (Semmelweis University, Hungary)
"The Role of Calcium Signaling in Formation and Function of Neutrophilic Granulocyte Derived Extracellular Vesicles"
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| 8:55 pm - 9:00 pm |
Discussion
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| 9:00 pm - 9:10 pm |
Ziv Roth (The Hospital for Sick Children, Canada)
"Differential Effect of M-CSF vs. GM-CSF on Macrophage Polarization"
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| 9:10 pm - 9:15 pm |
Discussion
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| 9:15 pm - 9:25 pm |
Fernando Montano Rendon (Hospital for Sick Children / University of Toronto, Canada)
"Phagosome Resolution Is Mediated by Contacts with the ER and PI4P Down Regulation"
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| 9:25 pm - 9:30 pm |
Discussion
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Sunday
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| 7:30 am - 8:30 am |
Breakfast
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| 9:00 am - 11:00 am |
Host-Pathogen Interaction
Discussion Leader: Gregory Olson (University of Washington, USA)
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| 9:00 am - 9:10 am |
Tobias Dallenga (Research Center Borstel, Germany)
"Neutrophils as Targets for Host-Directed Therapy Against Tuberculosis"
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| 9:10 am - 9:15 am |
Discussion
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| 9:15 am - 9:25 am |
Basel Abuaita (University of Michigan Medical School, USA)
"Mitochondria-Derived Vesicles Deliver Antimicrobial Payload to Control Phagosomal Bacteria"
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| 9:25 am - 9:30 am |
Discussion
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| 9:30 am - 9:40 am |
Rachel Kinsella (Washington University in St. Louis, USA)
"Investigating the Mechanism by Which ATG5 Controls Inflammation During Mycobacterium tuberculosis Infection"
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| 9:40 am - 9:45 am |
Discussion
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| 9:45 am - 9:55 am |
William Pandori (University of California, Irvine, USA)
"Regulation of IL-1β Production and Release During Toxoplasma gondii Infection of Primary Human Monocytes"
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| 9:55 am - 10:00 am |
Discussion
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| 10:00 am - 10:10 am |
Alissa Rothchild (Seattle Children's Research Institute, USA)
"Alveolar Macrophages Up-Regulate a Non-Classical Innate Response to Mycobacterium tuberculosis Infection In Vivo"
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| 10:10 am - 10:15 am |
Discussion
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| 10:15 am - 10:25 am |
Annica Stull-Lane (University of California, Davis, USA)
"NRAMP1/SLC11A1 Contributes to the Antimicrobial Response of Neutrophils"
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| 10:25 am - 10:30 am |
Discussion
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| 10:30 am - 10:40 am |
Johannes Westman (The Hospital for Sick Children, Canada)
"Regulation of Phagosomal Size and Integrity During Infection"
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| 10:40 am - 10:45 am |
Discussion
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| 10:45 am - 10:55 am |
Glenn Walpole (The Hospital for Sick Children, Canada)
"Inactivation of Rho Gtpases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Modulates Phagosome Maturation"
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| 10:55 am - 11:00 am |
Discussion
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| 11:00 am - 12:30 pm |
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
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| 12:30 pm - 1:30 pm |
Lunch
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| 1:30 pm - 2:30 pm |
Phagocytes in Disease
Discussion Leader: Fernando Montano Rendon (Hospital for Sick Children / University of Toronto, Canada)
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| 1:30 pm - 1:40 pm |
Sabine Arve (Lund University, Sweden)
"Neutrophil Extracellular Traps Serve as Antigens for Antinuclear Antibodies in Juvenile Idiopathic Arthritis"
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| 1:40 pm - 1:45 pm |
Discussion
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| 1:45 pm - 1:55 pm |
Mar Bosch Queralt (German Centre for Neurodegenerative Diseases, Germany)
"Impaired Lipid Handling by Phagocytes Prevents Myelin Regeneration in the Central Nervous System"
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| 1:55 pm - 2:00 pm |
Discussion
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| 2:00 pm - 2:10 pm |
Caterina Di Pietro (Yale University, USA)
"Pharmocological Induction of the HO-1/CO Pathway in Macrophages Ameliorates Cystic Fibrosis Lung Hyper-Inflammation"
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| 2:10 pm - 2:15 pm |
Discussion
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| 2:15 pm - 2:25 pm |
Hasan Oz (Yale School of Medicine, USA)
"Dysregulated Dynamics of Monocyte-Derived Macrophages During Pulmonary Chronic Inflammation Contribute to CF Airway Remodeling"
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| 2:25 pm - 2:30 pm |
Discussion
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| 2:30 pm - 3:00 pm |
Evaluation Period
Fill in GRS Evaluation Forms
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| 3:00 pm |
Seminar Concludes
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