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Phagocytes (GRS)

Gordon Research Seminar

Phagocyte Biology from Cell to System

June 1 - 2, 2019

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Chairs Philip Ostrowski and Venkatesh Krishnan

Contact Chairs

Waterville Valley

56 Packard's Road

Waterville Valley, NH, US

Venue and Travel Information

Application Information

Applications for this meeting must be submitted by May 4, 2019. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the conference chair if more seats become available due to cancellations.

GRS Speaker Abstract Deadline: Although applications will be accepted until the date noted above, any applicants who wish to be considered for an oral presentation should submit their application by March 1, 2019. Please refer to the application instructions in the Conference Description section below for more details (if available).

Conference Description

The Gordon Research Seminar on Phagocytes is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

GRS Phagocytes aims to present the latest discoveries in both basic and translational research with a unique perspective on the novel techniques used to study phagocyte biology. Topics will cover the origin, development, and function of phagocytes. The meeting format will be designed to maximize informal networking amongst attendees and presentation of research.

Application Instructions

The seminar will feature approximately 10 talks and 2 poster sessions. All attendees are expected to actively participate in the GRS, either by giving an oral presentation or presenting a poster. Therefore, all applications must include an abstract.

The seminar chair will select speakers from abstracts submitted by March 1, 2019. Those applicants who are not chosen for talks and those who apply after the deadline to be considered for an oral presentation will be expected to present a poster. In order to participate, you must submit an application by the date indicated in the Application Information section above.

Related Meeting

This GRS will be held in conjunction with the "Phagocytes" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
2:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm	New Methods and Models Discussion Leader: Claudia Rival (University of Virginia, USA)
3:45 pm - 3:55 pm	Kiran Roberts (University of Bristol, United Kingdom) "Ex Vivo Culture of Neutrophils as a Tool to Examine Neutrophil Cell Biology and Functionality"
3:55 pm - 4:00 pm	Discussion
4:00 pm - 4:10 pm	Kathryn Wierenga (Michigan State University, USA) "Omega-3 Fatty Acid Suppression of Silica-Induced Inflammasome Activation in a Novel Alveolar Macrophage Model"
4:10 pm - 4:15 pm	Discussion
4:15 pm - 4:25 pm	Julien Subburayalu (University of Cambridge, United Kingdom) "Killing Me Softly: An Unbiased Proteomic Approach to Identifying Novel 'Eat Me' Signatures on Apoptotic Neutrophils"
4:25 pm - 4:30 pm	Discussion
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Phagocytosis Discussion Leader: Pedro Marques (The Hospital for Sick Children, Canada)
7:30 pm - 7:40 pm	Paul Imbert (Peter Gilgan Centre for Research and Learning, SickKids, Canada) "The Role of the Macrophage Glycocalyx in Phagocytosis"
7:40 pm - 7:45 pm	Discussion
7:45 pm - 7:55 pm	Catherine Buckley (University of Birmingham, United Kingdom / The Hospital for Sick Children, Canada) "Mechanisms of Na+ Trafficking in Macropinosomes and Lysosomes"
7:55 pm - 8:00 pm	Discussion
8:00 pm - 8:10 pm	Anna D'Amico (Albany Medical College, USA) "PKC-E and Post-Golgi Trafficking During Phagocytosis"
8:10 pm - 8:15 pm	Discussion
8:15 pm - 8:25 pm	Therese de Neergaard (Lund University, Sweden) "Interaction-Normalized Assessment of Phagocytosis Reveals Non-Linear Igg-Fc Receptor Engagement Dependency"
8:25 pm - 8:30 pm	Discussion
8:30 pm - 8:40 pm	Saumil Sethna (University of Maryland School of Medicine, USA) "CIB2 Is Essential for Phagocytosis and Visual Function"
8:40 pm - 8:45 pm	Discussion
8:45 pm - 8:55 pm	Viktória Szeifert (Semmelweis University, Hungary) "The Role of Calcium Signaling in Formation and Function of Neutrophilic Granulocyte Derived Extracellular Vesicles"
8:55 pm - 9:00 pm	Discussion
9:00 pm - 9:10 pm	Ziv Roth (The Hospital for Sick Children, Canada) "Differential Effect of M-CSF vs. GM-CSF on Macrophage Polarization"
9:10 pm - 9:15 pm	Discussion
9:15 pm - 9:25 pm	Michelle Sugimoto (Federal University of Minas Gerais, Brazil) "Plasminogen and the Plasminogen Receptor, Plg-R KT, Regulate Macrophage Phenotypic and Functional Changes"
9:25 pm - 9:30 pm	Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Host-Pathogen Interaction Discussion Leader: Gregory Olson (University of Washington, USA)
9:00 am - 9:10 am	Tobias Dallenga (Research Center Borstel, Germany) "Neutrophils as Targets for Host-Directed Therapy Against Tuberculosis"
9:10 am - 9:15 am	Discussion
9:15 am - 9:25 am	Basel Abuaita (University of Michigan Medical School, USA) "Mitochondria-Derived Vesicles Deliver Antimicrobial Payload to Control Phagosomal Bacteria"
9:25 am - 9:30 am	Discussion
9:30 am - 9:40 am	Rachel Kinsella (Washington University in St. Louis, USA) "Investigating the Mechanism by Which ATG5 Controls Inflammation During Mycobacterium tuberculosis Infection"
9:40 am - 9:45 am	Discussion
9:45 am - 9:55 am	William Pandori (University of California, Irvine, USA) "Regulation of IL-1β Production and Release During Toxoplasma gondii Infection of Primary Human Monocytes"
9:55 am - 10:00 am	Discussion
10:00 am - 10:10 am	Alissa Rothchild (Seattle Children's Research Institute, USA) "Alveolar Macrophages Up-Regulate a Non-Classical Innate Response to Mycobacterium tuberculosis Infection In Vivo"
10:10 am - 10:15 am	Discussion
10:15 am - 10:25 am	Annica Stull-Lane (University of California, Davis, USA) "NRAMP1/SLC11A1 Contributes to the Antimicrobial Response of Neutrophils"
10:25 am - 10:30 am	Discussion
10:30 am - 10:40 am	Johannes Westman (The Hospital for Sick Children, Canada) "Regulation of Phagosomal Size and Integrity During Infection"
10:40 am - 10:45 am	Discussion
10:45 am - 10:55 am	Glenn Walpole (The Hospital for Sick Children, Canada) "Inactivation of Rho Gtpases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Modulates Phagosome Maturation"
10:55 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Phagocytes in Disease Discussion Leader: Fernando Montano Rendon (Hospital for Sick Children / University of Toronto, Canada)
1:30 pm - 1:40 pm	Sabine Arve (Lund University, Sweden) "Neutrophil Extracellular Traps Serve as Antigens for Antinuclear Antibodies in Juvenile Idiopathic Arthritis"
1:40 pm - 1:45 pm	Discussion
1:45 pm - 1:55 pm	Mar Bosch Queralt (German Centre for Neurodegenerative Diseases, Germany) "Impaired Lipid Handling by Phagocytes Prevents Myelin Regeneration in the Central Nervous System"
1:55 pm - 2:00 pm	Discussion
2:00 pm - 2:10 pm	Caterina Di Pietro (Yale University, USA) "Pharmocological Induction of the HO-1/CO Pathway in Macrophages Ameliorates Cystic Fibrosis Lung Hyper-Inflammation"
2:10 pm - 2:15 pm	Discussion
2:15 pm - 2:25 pm	Hasan Oz (Yale School of Medicine, USA) "Dysregulated Dynamics of Monocyte-Derived Macrophages During Pulmonary Chronic Inflammation Contribute to CF Airway Remodeling"
2:25 pm - 2:30 pm	Discussion
2:30 pm - 3:00 pm	Evaluation Period Fill in GRS Evaluation Forms
3:00 pm	Seminar Concludes

Contributors

Funding for this conference was made possible [in part] by 1 R13 AI 143196 - 01 from the National Institute of Allergy and Infectious Diseases. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

Conference Links

Conference History Phagocytes Contribute Financially to This Conference

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Poster Information

Poster sessions are an integral part of the our conferences, and offer all conferees an opportunity to discuss their research.

Preparing your GRC poster

Diversity Funding

Financial assistance is available for qualified applicants through the GRC Carl Storm Underrepresented Minority Fellowship Program. This program provides a grant to underrepresented minority graduate students, postdocs, faculty and scientists to help fund their attendance at their first GRC meeting. Learn more.

Registration Fees

Conferee Single Room:

$285.00

Conferee Shared Room:

$265.00

Conferee Off-Site:

$190.00

Guest Single Room:

$285.00

Guest Shared Room:

$265.00

Guest Off-Site:

$190.00

Child 4-12 yrs Shared Room:

$133.00

Child 4-12 yrs Off-Site:

$95.00

Child Under 4 yrs Shared Room:

Free

Child Under 4 yrs Off-Site:

Free

Bus Arriving:

$45.00

Additional Fee Info

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Phagocytes

June 2 - 7, 2019

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