Conference Description
The 2022 Gordon Research Conference on Post-Transcriptional Gene Regulation will be the ninth in a biennial series that began in 2004. The 2022 meeting will discuss the newest findings on the basic mechanisms that underlie the expression of RNAs, starting from their synthesis by RNA polymerases to their translation and destruction in the cytoplasm. The overall aim is to understand the multifaceted roles for RNA in physiology, development and genetic diseases. Areas of emphasis will include crosstalk between steps in RNA processing, mechanisms of splicing and 3' end processing, RNA localization and decay, translational control and how alterations in RNA regulation contribute to human disease. Emphasis will also be given to cutting-edge computational and experimental approaches.
An important goal of the meeting is to foster interactions between academic and industrial scientists that lead to the identification of novel drug targets and facilitate their development. The meeting will include approximately 40 invited speakers from academia and industry representing a variety of post-transcriptional control topics in nine sessions. In addition, short talks will be selected from submitted abstracts. Four late afternoon poster sessions will ensure that the science of every participant will be discussed in depth. The overall attendance will be limited to ~180 participants. Sessions will generally have 4-6 speakers each.
The topics, speakers, and discussion leaders for the conference sessions are displayed below. The conference chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by March 10, 2022. Please check back for updates.
Emerging Concepts in RNA Biology
Discussion Leaders
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Joan Steitz (Yale University , USA)
Speakers
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Christine Mayr (Memorial Sloan Kettering Cancer Center, USA)
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Mitch Guttman (California Institute of Technology, USA)
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Benjamin Blencowe (University of Toronto, Canada)
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Roy Parker (University of Colorado Boulder, USA)
Role of Post-Transcriptional Regulation From Genotype to Phenotype
Discussion Leaders
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Brenton Graveley (UConn Health, USA)
Speakers
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Xinshu Xiao (University of California, Los Angeles, USA)
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Juan Valcarcel (Centre for Genomic Regulation (CRG), Spain)
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Alain Laederach (University of North Carolina at Chapel Hill, USA)
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Angela Brooks (University of California, Santa Cruz, USA)
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Auinash Kalsotra (University of Illinois at Urbana-Champaign, USA)
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William Fairbrother (Brown University, USA)
3’ Processing
Discussion Leaders
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Chris Burge (Massachusetts Institute of Technology, USA)
Speakers
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Eric Wagner (University of Texas Medical Branch, USA)
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Bin Tian (The Wistar Institute, USA)
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Yongsheng Shi (University of California, Irvine, USA)
RNA Decay
Discussion Leaders
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Karla Neugebauer (Yale University, USA)
Speakers
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Lynne Maquat (University of Rochester Medical Center, USA)
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Olivia Rissland (University of Colorado Denver, USA)
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Bobby Hogg (National Institutes of Health, USA)
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Heidi Cook-Andersen (University of California, San Diego, USA)
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Sujatha Jagannathan (University of Colorado Anschutz Medical Campus, USA)
RNA Structure and Modifications
Discussion Leaders
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Wendy Gilbert (Yale University, USA)
Speakers
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Steve Bonilla (University of Colorado, USA)
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Richard Gregory (Boston Children's Hospital / Harvard Medical School, USA)
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Kathy Fange Liu (The University of Pennsylvania, USA)
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Rui Zhao (University of Colorado Anschutz Medical Campus, USA)
Translational
Discussion Leaders
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Ruth Lehmann (Massachusetts Institute of Technology,, USA)
Speakers
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Katrin Karbstein (The Scripps Research Institute, USA)
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Davide Ruggero (University of California, San Francisco, USA)
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Gloria Brar (University of California, Berkeley, USA)
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Joel Neilson (Baylor College of Medicine, USA)
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Jeff Coller (Case Western Reserve University, USA)
RNA Localization and Assembly
Discussion Leaders
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Douglas Black (University of California, Los Angeles, USA)
Speakers
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Kimberly Mowry (Brown University, USA)
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Robin Stanley (National Institute of Environmental Health Sciences, NIH, USA)
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Lingling Chen (Shanghai Institutes for Biological Sciences, CAS, China)
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Beatriz Fontoura (University of Texas Southwestern Medical Center, USA)
RNP Function and Disease Implications
Discussion Leaders
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Manuel Ares (University of California, Santa Cruz, USA)
Speakers
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Eric Wang (University of Florida, USA)
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Sara Cherry (University of Pennsylvania, USA)
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Kathryn Hamilton (University of Pennsylvania, USA)
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Peter Sarnow (Stanford University, USA)
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Adrian Krainer (Cold Spring Harbor Laboratory, USA)
Integration of RNA Biogenesis Steps
Discussion Leaders
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Nicholas Conrad (University of Texas Southwestern Medical Center, USA)
Speakers
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Tracy Johnson (University of California, Los Angeles, USA)
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Matthew Simon (Yale University, USA)
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David Bentley (University of Colorado Denver, USA)
The GRC Power Hour™
Organizers:
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Kristen Lynch (University of Pennsylvania, USA)
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Karla Neugebauer (Yale University, USA)
