| SUNDAY | 
| 2:00 pm - 9:00 pm | Arrival and Check-in | 
| 6:00 pm | Dinner | 
| 7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff | 
| 7:40 pm - 9:30 pm | Poster Presentations / New Channels | 
|  | Discussion Leader: Carol Deutsch (University of Pennsylvania) | 
| 7:40 pm - 8:20 pm | Poster Previews I | 
|  | Rapid-Fire Presentations by Post-Docs and Graduate Students | 
| 8.20 pm - 8:45 pm | David Clapham (Harvard U.) "Ion Channels in Cilia and What They Do"
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| 8:45 pm - 8:55 pm | Discussion | 
| 8:55 pm - 9:20 pm | Stephen Long (Memorial Sloan Kettering Cancer Center) "Structural and Functional Analysis of a Eukaryotic Anion Channel"
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| 9:20 pm - 9:30 pm | Discussion | 
| MONDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 8:30 am | Group Photo | 
| 9:00 am - 12:30 pm | Channel Childhood: Trafficking and Regulators | 
|  | Discussion Leader: Fred Sigworth (Yale University) | 
| 9:00 am - 9:25 am | Lily Jan (UCSF) "Adolescent Channels in the TMEM16 Family"
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| 9:25 am - 9:35 am | Discussion | 
| 9:35 am - 10:00 am | Chris Lingle (Washington University) "BK Channel Regulation by Auxiliary Subunits"
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| 10:00 am - 10:10 am | Discussion | 
| 10:10 am | Coffee Break | 
| 10:30 am - 10:55 am | Show-Ling Shyng (OHSU) "Pharmacological Chaperoning of Trafficking-Impaired KATP Channels"
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| 10:55 am - 11:05 am | Discussion | 
| 11:05 am - 11:30 am | Paul Welling (U. Maryland) "Clathrin Adaptors Bringeth and Taketh Kir Channels"
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| 11:30 am - 11:40 am | Discussion | 
| 11:40 am - 11:55 am | Indra Schroeder (Technical University of Darmst, Germany) "Viral Potassium Channels as a Model System for Structure-Function Relations"
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| 11:55 am - 12:05 pm | Discussion | 
| 12:05 pm - 12:30 pm | Poster Previews II | 
|  | Rapid-Fire Presentations by Post-Docs and Graduate Students | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 6:00 pm | Poster Session | 
| 6:00 pm | Dinner | 
| 7:30 pm - 9:30 pm | Channel Adolescence: New Partners | 
|  | Discussion Leader: Bill Kobertz (University of Massachusetts) | 
| 7:30 pm - 7:55 pm | Bernd Fakler (University of Freiburg) "Native AMPA-Receptor Channels - Insights from Functional Proteomics"
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| 7:55 pm - 8:05 pm | Discussion | 
| 8:05 pm - 8:30 pm | Geoff Abbott (UC Irvine) "Channel-Transporter Interactions"
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| 8:30 pm - 8:40 pm | Discussion | 
| 8:40 pm - 8:55 pm | Randy Stockbridge (Brandeis University) "Dual Topology of a Microbial Fluoride Channel"
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| 8:55 pm - 9:00 pm | Discussion | 
| 9:00 pm - 9:25 pm | Heather Pinkett (University of Pennsylvania) "Implications in the Classification of Bacterial ABC Transporters"
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| 9:25 pm - 9:30 pm | Discussion | 
| TUESDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am - 12:30 pm | Channel Life I: Gating and Permeating | 
|  | Discussion Leader: William Zagotta (University of Washington) | 
| 9:00 am - 9:25 am | Teresa Giraldez (ULL, Spain) "BK Channel Gating-Ring Motions During Activation"
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| 9:25 am - 9:35 am | Discussion | 
| 9:35 am - 10:00 am | Simon Berneche (University of Basel, Switzerland) "Mechanisms of Activation and Inactivation at the Selectivity Filter of K Channels"
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| 10:00 am - 10:10 am | Discussion | 
| 10:10 am | Coffee Break | 
| 10:40 am - 11:05 am | Steve Lockless (Texas A&M University) "Equilibrium Ion Binding Properties of Tetrameric Cation Channels"
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| 11:05 am - 11:15 am | Discussion | 
| 11:15 am - 11:40 am | Youxing Jiang (UTSW) "On the Origin of Ion Selectivity in K Channels""
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| 11:40 am - 11:50 am | Discussion | 
| 11:50 am - 12:15 pm | Tom DeCoursey (Rush University) "Voltage-Gated Proton Channels: VSDs with Attitude"
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| 12:15 pm - 12:30 pm | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 6:00 pm | Poster Session | 
| 6:00 pm | Dinner | 
| 7:30 pm - 9:30 pm | Channel Life II: Membranes and Toxins | 
|  | Discussion Leader: TBA | 
| 7:30 pm - 7:55 pm | Eric Lingueglia (University of Nice, France) "Peptide Toxins to Explore the Role of Acid-Sensing Ion Channels in Pain"
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| 7:55 pm - 8:05 pm | Discussion | 
| 8:05 pm - 8:30 pm | Mounir Tarek (University of Lorraine, France) "On Activation and Lipid Modulation of Kv Channels Gating from Molecular Dynamics Simulations"
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| 8:30 pm - 8:40 pm | Discussion | 
| 8:40 pm - 9:05 pm | Qiuxing Jiang (UTSW) "Lipid-Dependent Gating Effects on Voltage-Gated Potassium Channels"
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| 9:05 pm - 9:10 pm | Discussion | 
| 9:10 pm - 9:25 pm | Elwin van der Cruijsen (Utrecht University, Holland) "Dissecting Protein Structure and Dynamics in Membranes During the Gating Cycle of a Potassium Channel"
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| 9:25 pm - 9:30 pm | Discussion | 
| WEDNESDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am - 12:30 pm | Channel Lifestyle I: Drugs and Para(pharm)ernalia | 
|  | Discussion Leader: Kenton Swartz (NIH) | 
| 9:00 am - 9:25 am | Owen McManus (Essen Biosciences) "Ion Channel Therapeutics: New Ideas from Both Sides of the Fence"
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| 9:25 am - 9:35 am | Discussion | 
| 9:35 am - 10:00 am | Cindy Czajkowski (University of Wisconsin) "Pentameric Ligand Gated Ion Channels: Uncovering the Motions Underlying Ligand-Driven Conformational Transitions"
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| 10:00 am - 10:10 am | Discussion | 
| 10:10 am | Coffee Break | 
| 10:40 am - 11:05 am | David Fedida (University of BC, Canada) "Ion Channel Blockers for Therapeutics: From Theory into Practice, Today and Tomorrow"
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| 11:05 am - 11:15 am | Discussion | 
| 11:15 am - 11:40 am | Jerod Denton (Vanderbilt University) "Small-Molecule Probes of Kir Channel Structure, Function, and Druggability"
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| 11:40 am - 11:50 am | Discussion | 
| 11:50 am - 12:05 pm | Gareth Young (Pfizer Neusentis, UK) "Characterizing Human Stem Cell Derived Sensory Neurons at the Single Cell Level Reveals Their Ion Channel Expression and Utility in Pain Research"
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| 12:05 pm - 12:10 pm | Discussion | 
| 12:10 pm - 12:25 pm | Len Kaczmarek (Yale University) "Human Gain-of-Function Slack Potassium Channel Mutations Alter Channel Cooperativity and Signaling Protein Interactions"
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| 12:25 pm - 12:30 pm | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 6:00 pm | Poster Session | 
| 6:00 pm | Dinner | 
| 7:00 pm - 7:30 pm | Business Meeting | 
|  | Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair | 
| 7:30 pm - 9:30 pm | Channel Lifestyle II: Channels in Specialized Places | 
|  | Discussion Leader: Bertil Hille (University of Washington) | 
| 7:30 pm - 7:55 pm | Dejian Ren (University of Pennsylvania) "Lysosomal ATP-Sensitive TPC Na+ Channels and Their Regulation"
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| 7:55 pm - 8:05 pm | Discussion | 
| 8:05 pm - 8:30 pm | Ellen Lumpkin (Columbia University) "Mechanotransduction Channels in Epidermal Cells"
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| 8:30 pm - 8:40 pm | Discussion | 
| 8:40 pm - 9:05 pm | Ardem Patapoutian (Scripps Inst.) "How Do You Feel? Ion Channels That Sense Mechanical Force"
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| 9:05 pm - 9:10 pm | Discussion | 
| 9:10 pm - 9:25 pm | Monica Sala-Rabanal (Washington University in Saint Louis) "Secreted CLCA1 Modulates Anoctamin1/TMEM16A to Activate Ca2+-Dependent Chloride Currents in Human Cells"
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| 9:25 pm - 9:30 pm | Discussion | 
| THURSDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am - 12:30 pm | Channel Surgery: Engineering, Modification and New Methods | 
|  | Discussion Leader: Gary Yellen (Harvard University) | 
| 9:00 am - 9:25 am | Pancho Bezanilla (University of Chicago) "Down the Path of the Sensor Charges!"
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| 9:25 am - 9:35 am | Discussion | 
| 9:35 am - 10:00 am | Katie Henzler-Wildman (Washington University) "(Non)selectivity in Transporters and Channels: A Resonant Perspective"
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| 10:00 am - 10:10 am | Discussion | 
| 10:10 am | Coffee Break | 
| 10:40 am - 11:05 am | Peter Hegemann (Humboldt  University, Germany) "Conversion of Channelrhodopsin into a Light-Gated Chloride Channel"
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| 11:05 am - 11:15 am | Discussion | 
| 11:15 am - 11:40 am | David Drew (Stockholm University, Sweden) "Tools and Structures to Unravel the Ins and Outs of SLC Transport"
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| 11:40 am - 11:50 am | Discussion | 
| 11:50 am - 12:05 pm | Francis Valiyaveetil (Oregon Health and Sciences University) "Using Unnatural Mutagenesis to Investigate C-Type Inactivation in K+ Channels"
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| 12:05 pm - 12:10 pm | Discussion | 
| 12:10 pm - 12:25 pm | Zhaozhu Qiu (Scripps Research Inst.) "SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel"
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| 12:25 pm - 12:30 pm | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 6:00 pm | Poster Session | 
| 6:00 pm | Dinner | 
| 7:30 pm - 9:30 pm | Channel Infirmity: Channels and Diseases | 
|  | Discussion Leader: Chris Miller (Brandeis University) | 
| 7:30 pm - 7:55 pm | Fran Ashcroft (Oxford University, UK) "Neonatal Diabetes: A Unique K Channelopathy"
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| 7:55 pm - 8:10 pm | Discussion | 
| 8:10 pm - 8:35 pm | Annette Dolphin (UCL, UK) "Neuronal Voltage Gated Calcium Channel Trafficking and Neuropathic Pain"
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| 8:35 pm - 8:50 pm | Discussion | 
| 8:50 pm - 9:15 pm | Geoff Pitt (Duke University) "Voltage-Gated Ca Channel Dysfunction in Non-Excitable Tissues: New Mechanisms for Birth Defects"
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| 9:15 pm - 9:30 pm | Discussion | 
| FRIDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am | Departure |