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Collagen
Gordon Research Conference

The Multifaceted Nature of Collagens in Development, Disease and Tissue Repair

Dates

July 16-21, 2017

Location

Colby-Sawyer College
New London, NH Site Information

Organizers

Chair:
Florence P. Ruggiero

Vice Chair:
Marion K. Gordon

Application Deadline

Applications for this meeting must be submitted by June 18, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

Meeting Description

Collagens form a superfamily of 28 members that show a remarkable diversity in molecular and supramolecular organization, tissue distribution and function. They play a unique role in providing a supportive scaffold to which cells attach and in maintaining the structural integrity of many tissues. Collagens are multidomain interactive proteins that can bind simultaneously to cell surface receptors and other extracellular matrix molecules to exert their numerous function. From evidence of the recent years, collagens clearly display both regulatory and mechanical function during development, tissue maintenance and repair. The critical roles of collagens have been illustrated by the wide spectrum of diseases, commonly named "collagenopathies", that affect various organs and tissues. Fibrotic disorders result from an imbalance from collagen synthesis and breakdown. Understanding the functional diversity of collagens and their mechanisms of action has thus significant and broad impact on human health issues. Although unexpected and very diverse collagen functions have been discovered in recent years, it is more than likely that the structural and functional landscape of the collagen superfamily is still far from being complete.

The 2017 Collagen GRC intends to be the international scene of major findings, new concepts related to the field of collagen research and to provide a framework for future research. The 2017 GRC program will specifically focus on the amazing diverse function of collagens in development, disease and tissue repair. The sessions will provide updates on important topics as Molecular and Functional Aspects of Collagen Biosynthesis, Collagens of the Basement Membrane Zone, Cells in their Collagen Microenvironments, and Collagens in Inherited and Common diseases and Therapies. Relevantly, the conference will also include emerging topics as Collagens as Dynamic Regulators of Network, Collagen in Aging and Metabolism, Collagens in Development and Regeneration, Bioengineering Collagen Microenvironements and Mechanobiology and a session focussed on Technology Advances and Emerging Directions for Collagen Research. The conference will also reserve slots for late-breaking topics and graduate students and postdoctoral fellows selected from the Collagen Gordon Research Seminar (GRS). This conference is a unique forum for the development of fruitful and intense interactions between young and senior researchers, and newcomers in the collagen field and for exchanges of new ideas. Graduate students and postdoctoral fellows are strongly encouraged to attend both the GRS and GRC.

Related Meeting

This GRC will be held in conjunction with the "Collagen" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Contributors

Preliminary Program

The topics and speakers for the conference sessions are displayed below (italics denote discussion leaders). The Conference Chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by March 16, 2017. Please check back for updates.

  • Keynote Session: From Gene Regulation to Functional Aspects of Collagen Biosynthesis
    (John Bateman / Hiroshi Asahara / Paul Gissen / Hans-Peter Bachinger)
  • Collagens as Dynamic Regulators of Networks
    (Erhard Hohenester / Irit Sagi / Steven Van Doren / Richard Farndale / David Hulmes)
  • Cells in Collagen Microenvironments
    (Valerie Weaver / Peter Friedl / Fiona Watt / Sufi M. Thomas)
  • Collagens of the Basement Membrane Zone: Assembly and Disease
    (Leena Bruckner-Tuderman / Billy Hudson / Rachel Lennon / Alexander Nystrom)
  • Collagens in Ageing and Metabolism
    (Sergey Leikin / Collin Ewald / Taina Pilhajaniemi)
  • Collagens in Development and Regeneration
    (Sally Horne-Badovinac / Michael Granato / Andrea Page-McCaw / Catherina Becker / Alessandra Sacco)
  • 3D Bioengineering and Mechanobiology
    (Fiona Watt / Valerie Weaver / Andrew Doyle / Joseph Freeman)
  • Collagens in Inherited and Common Diseases and Therapies
    (Fransiska Malfait / Alexandra Naba / John Bateman / David Birk)
  • Technology Advances and Emerging Directions for Collagen Research
    (Alexandra Naba / Ulrich Auf Dem Keller / Marie-Claire Schanne-Klein)
  • Power Hour
    (Marion Gordon, Taina Pilhajaniemi)

Funding for this conference was made possible by the National Institute of Arthritis and Musculoskeletal and Skin Disease (NIAMS). The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
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