Gordon Research Conferences
Meeting Details

Plasminogen Activation & Extracellular Proteolysis
Gordon Research Conference

Biological Functions and Translational Importance of Plasminogen Activation and Extracellular Proteolysis


February 11-16, 2018


Four Points Sheraton / Holiday Inn Express
Ventura, CA Site Information


Manuel Yepes

Vice Chairs:
Stella E. Tsirka & Marie Ranson

Application Deadline

Applications for this meeting must be submitted by January 14, 2018. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

Meeting Description

The main goal of this meeting is to present breakthrough findings on the biological functions of plasminogen activation and extracellular proteolysis and to discuss their translational importance in distinct scientific areas: vascular biology, neurobiology, neurodegeneration, cell death, pregnancy, cardiovascular and renal function, inflammation, infection, tissue homeostasis and regeneration, tumor biology, cardiovascular function, and angiogenesis. Each topic will be addressed within a conceptual framework assembled by three "T's": Translational, Technological and Transitional. The Translational goal will be met by in-depth discussions of the translational importance of the new discoveries presented in each session and the identification of those basic research areas that need to be developed in the future to meet specific clinical needs. These discussions will be accompanied by the presentation and discussion of state-of-the-art Technological advances in proteomics, genomics and imaging. Finally, to promote a Transition to a new generation of investigators, each session will be assembled by a mixed group of senior and younger speakers.

Related Meeting

This GRC will be held in conjunction with the "Plasminogen Activation & Extracellular Proteolysis" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.


Gordon Research Conferences

Session Titles

The Conference will consist of nine sessions, on the topics listed below. The Conference Chair is currently developing their preliminary program, which will include the names of the invited speakers and discussion leaders for each of these sessions. The preliminary program will be available by July 1, 2017. Please check back for updates.

  • Keynote Session: Translational Impact of More than 80 Years of Research on Plasminogen Activation and Extracellular Proteolysis
  • Proteases in Neurobiology: From the Synapse to the Bedside
  • Proteases in Cardiovascular and Renal Function
  • Proteases in Inflammation, Infection and Pregnancy
  • Structure and Function of Proteases, Receptors and Inhibitors
  • Proteases in Cancer
  • Late-Breaking Topics
  • Proteases in Aging, Cell Death and Neurodegeneration
  • New Technologies and Therapeutic Advances in Plasminogen Activation and Extracellular Proteolysis
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