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Viruses & Cells
Gordon Research Conference

Biology, Pathogenesis, and Treatment of Viral Infections

Dates

May 14-19, 2017

Location

Renaissance Tuscany Il Ciocco
Lucca (Barga), Italy Site Information

Organizers

Chair:
Blossom Damania

Vice Chair:
Julie Pfeiffer

Application Deadline

Applications for this meeting must be submitted by April 16, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

Meeting Description

The 2017 Viruses and Cells GRC, the premier conference in the field of virology, will cover seminal topics in virology ranging from viral entry and structure to virus-host interactions, viral replication, immune responses to viral infection, and viral therapeutics.

The 2017 meeting will be held at Renaissance Tuscany, Il Ciocco, Lucca (Barga), Italy, from May 14-19, 2017. The conference is an interactive forum which brings together investigators at the forefront of the field, junior investigators launching their independent research careers, graduate students and postdoctoral fellows, and investigators from NIH and industry. The conference strives to represent a collegial environment that supports the discussion of novel ideas and fosters new collaborations.

Invited speakers will present novel and cutting edge findings in the field of virology. Topics will include: viral structure and entry, the immune response to viral infection, viral evasion of host immunity, viral replication and persistence, viral pathogenesis, virus-host interactions, modulation of cellular pathways by viruses, viruses and cancer, and viral therapeutics. Session chairs who are experts on the topic covered in each session will lead interactive, lively, and open discussions following each presentation.

In addition to each of the invited speakers, short talks will be chosen from the abstracts that are submitted to the meeting at the time of registration. Abstracts that highlight the most exciting and new developments in the field of virology will be selected for short talks, and the remainder of the abstracts will be selected as posters. The evening poster sessions are a prominent and important aspect of this conference providing yet another opportunity for participants to interact and discuss their research findings in an informal, friendly atmosphere.

Related Meeting

This GRC will be held in conjunction with the "Viruses & Cells" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Contributors

Meeting Program

Sunday
4:00 pm - 8:00 pmArrival and Check-in
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmVirus Structure and Entry
Discussion Leader: Michael Imperiale (University of Michigan, USA)
7:40 pm - 8:00 pmSean Whelan (Harvard Medical School, USA)
"Structure and Inhibition of the Replication Machinery of Negative Sense RNA Viruses"
8:00 pm - 8:10 pmDiscussion
8:10 pm - 8:30 pmRichard Longnecker (Northwestern University, USA)
"Epstein-Barr Virus Entry"
8:30 pm - 8:40 pmDiscussion
8:40 pm - 9:00 pmFelix Rey (Institut Pasteur, France)
"Influenza Virus Capsid Uncoating"
9:00 pm - 9:05 pmDiscussion
9:05 pm - 9:25 pmAri Helenius (ETH Zurich, Switzerland)
"Structurally Identified Homology Between Viral and Cellular Membrane Fusion Proteins Highlights the Impact of Genetic Exchanges in the Evolution of Eukaryotic Organisms"
9:25 pm - 9:30 pmDiscussion
Monday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmThe Immune Response to Viral Infection
Discussion Leaders: Ralph Baric (University of North Carolina at Chapel Hill, USA) and Carolina Lopez (University of Pennsylvania, USA)
9:00 am - 9:20 amHerbert Virgin (Washington University School of Medicine, USA)
"Role of the Virome in Control of Immunity, and Vice Versa"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amZhijian James Chen (University of Texas Southwestern Medical Center, USA)
"Innate Immune Sensing of DNA Viruses and Retroviruses by cGAS"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amAna Fernandez-Sesma (Icahn School of Medicine at Mount Sinai, USA)
"Immune Evasion Mechanisms by Flaviviruses and Beyond"
10:20 am - 10:30 amDiscussion
10:30 am - 11:00 amCoffee Break
11:00 am - 11:20 amCharles Rice (The Rockefeller University, USA)
"Unraveling Nature's Intrinsic and Innate Antiviral Defenses"
11:20 am - 11:30 amDiscussion
11:30 am - 11:40 amShort Talk Selected from Poster Abstracts
11:40 am - 11:45 amDiscussion
11:45 am - 11:55 amShort Talk Selected from Poster Abstracts
11:55 am - 12:00 pmDiscussion
12:00 pm - 12:10 pmShort Talk Selected from Poster Abstracts
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:25 pmShort Talk Selected from Poster Abstracts
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:30 pmFree Time
4:30 pm - 6:00 pmPoster Session
6:00 pm - 8:00 pmViral Replication and Persistence
Discussion Leaders: Andrew Pekosz (Johns Hopkins University, USA) and Laurie Krug (Stony Brook University, USA)
6:00 pm - 6:20 pmRonald Desrosiers (University of Miami, USA)
"Codon Usage and the Early-Late Transition Among Persisting Viruses"
6:20 pm - 6:30 pmDiscussion
6:30 pm - 6:50 pmCarolyn Coyne (University of Pittsburgh, USA)
"Breaking Barriers: Viral Infections of Polarized Cells"
6:50 pm - 7:00 pmDiscussion
7:00 pm - 7:20 pmStacey Schultz-Cherry (St. Jude Children's Research Hospital, USA)
"Defining the Cellular Factors Regulating Astrovirus Replication"
7:20 pm - 7:30 pmDiscussion
7:30 pm - 7:50 pmRolf Renne (University of Florida, USA)
"Long and Short Non-Coding RNAs in KSHV Biology and Pathogenesis"
7:50 pm - 8:00 pmDiscussion
8:00 pmDinner
Tuesday
7:30 am - 8:30 amBreakfast
8:30 amGroup Photo
9:00 am - 12:30 pmViral Pathogenesis
Discussion Leaders: Lynn Enquist (Princeton University, USA) and Matthew Evans (Icahn School of Medicine at Mount Sinai, USA)
9:00 am - 9:20 amJulie Overbaugh (Fred Hutchinson Cancer Research Center, USA)
"Immune Responses to HIV in Mothers and Their Infants"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amLisa Ng (Singapore Immunology Network (SIgN), A*STAR, Singapore)
"Cell and Molecular Mechanisms of Alphavirus Pathogenesis"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amMartha Clokie (University of Leicester, United Kingdom)
"Bacteriophages to Treat Antibiotic Resistant Bacteria"
10:20 am - 10:30 amDiscussion
10:30 am - 11:00 amCoffee Break
11:00 am - 11:20 amChristiane Wobus (University of Michigan Medical School, USA)
"Overcoming the Epithelial Barrier: The Tale of a Norovirus"
11:20 am - 11:30 amDiscussion
11:30 am - 11:40 amShort Talk Selected from Poster Abstracts
11:40 am - 11:45 amDiscussion
11:45 am - 11:55 amShort Talk Selected from Poster Abstracts
11:55 am - 12:00 pmDiscussion
12:00 pm - 12:10 pmShort Talk Selected from Poster Abstracts
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:25 pmShort Talk Selected from Poster Abstracts
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:30 pmFree Time
4:30 pm - 6:00 pmPoster Session
6:00 pm - 8:00 pmVirus-Host Interactions
Discussion Leaders: Chris Sullivan (University of Texas at Austin, USA) and Kartik Chandran (Albert Einstein College of Medicine, USA)
6:00 pm - 6:20 pmRozanne Sandri-Goldin (University of California, Irvine, USA)
"Structure-Function Analysis of a Signature Multifunctional Herpesvirus Protein"
6:20 pm - 6:30 pmDiscussion
6:30 pm - 6:50 pmKanta Subbarao (WHO Collaborating Centre for Reference and Research on Influenza, Australia)
"Viral and Host Determinants of Influenza Virus Transmission"
6:50 pm - 7:00 pmDiscussion
7:00 pm - 7:20 pmNels Elde (University of Utah, USA)
"Viral Adaptation Through Retrotransposition"
7:20 pm - 7:30 pmDiscussion
7:30 pm - 7:40 pmShort Talk Selected from Poster Abstracts
7:40 pm - 7:45 pmDiscussion
7:45 pm - 7:55 pmShort Talk Selected from Poster Abstracts
7:55 pm - 8:00 pmDiscussion
8:00 pmDinner
Wednesday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmVirus Biology
Discussion Leaders: Britt Glaunsinger (University of California, Berkeley, USA) and Micah Luftig (Duke University Medical Center, USA)
9:00 am - 9:20 amJoan Steitz (Yale University, USA)
"Viral Noncoding RNAs: More Surprises"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amCarla Saleh (Pasteur Institute, France)
"A New Dimension in Insect Antiviral Immunity"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amFelicia Goodrum (University of Arizona, USA)
"Cytomegalovirus Regulation of Host Trafficking and Signaling to Affect Latency"
10:20 am - 10:30 amDiscussion
10:30 am - 11:00 amCoffee Break
11:00 am - 11:10 amShort Talk Selected from Poster Abstracts
11:10 am - 11:15 amDiscussion
11:15 am - 11:25 amShort Talk Selected from Poster Abstracts
11:25 am - 11:30 amDiscussion
11:30 am - 11:40 amShort Talk Selected from Poster Abstracts
11:40 am - 11:45 amDiscussion
11:45 am - 11:55 amShort Talk Selected from Poster Abstracts
11:55 am - 12:00 pmDiscussion
12:00 pm - 12:10 pmShort Talk Selected from Poster Abstracts
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:25 pmShort Talk Selected from Poster Abstracts
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:30 pmFree Time
4:30 pm - 6:00 pmPoster Session
6:00 pm - 8:00 pmViral Modulation of Host Immunity
Discussion Leaders: Melanie Brinkmann (Helmholtz Centre for Infection Research, Germany) and Stacy Horner (Duke University Medical Center, USA)
6:00 pm - 6:20 pmSoren Paludan (University of Aarhus, Denmark)
"Evasion of Innate Immune Responses by Viruses"
6:20 pm - 6:30 pmDiscussion
6:30 pm - 6:50 pmMark Heise (University of North Carolina at Chapel Hill, USA)
"Identification of Novel Viral and Host Genetic Elements Impacting Alphavirus Pathogenesis"
6:50 pm - 7:00 pmDiscussion
7:00 pm - 7:20 pmJoanna Shisler (Univeristy of Illinois at Urbana-Champaign, USA)
"Poxvirus Inhibition of Intrinsic Innate Immune Responses: What Viruses Can Teach Us About Cellular Anti-Viral Mechanisms"
7:20 pm - 7:30 pmDiscussion
7:30 pm - 7:40 pmShort Talk Selected from Poster Abstracts
7:40 pm - 7:45 pmDiscussion
7:45 pm - 7:55 pmShort Talk Selected from Poster Abstracts
7:55 pm - 8:00 pmDiscussion
8:00 pmDinner
Thursday
7:30 am - 8:30 amBreakfast
8:30 am - 9:00 amBusiness Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pmViruses and Cancer
Discussion Leader: Robert Yarchoan (National Cancer Institute, NIH, USA)
9:00 am - 9:20 amYuan Chang (University of Pittsburgh, USA)
"MCV Small T Antigen and the Mitotic Environment"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amErle Robertson (University of Pennsylvania, USA)
"Epigenetics of EBV Early Infection Control"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amLaimonis Laimins (Northwestern University, USA)
"Human Papillomaviruses and DNA Damage Responses"
10:20 am - 10:30 amDiscussion
10:30 am - 11:00 amCoffee Break
11:00 am - 11:20 amEthel Cesarman (Weill Cornell Medicine, USA)
"Targeting Viral Oncogenic Signals"
11:20 am - 11:30 amDiscussion
11:30 am - 11:40 amShort Talk Selected from Poster Abstracts
11:40 am - 11:45 amDiscussion
11:45 am - 11:55 amShort Talk Selected from Poster Abstracts
11:55 am - 12:00 pmDiscussion
12:00 pm - 12:10 pmShort Talk Selected from Poster Abstracts
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:25 pmShort Talk Selected from Poster Abstracts
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:30 pmFree Time
4:30 pm - 6:00 pmPoster Session
6:00 pm - 8:00 pmViral Therapeutics and Vaccines
Discussion Leaders: Terence Dermody (University of Pittsburgh, USA) and Sankar Swaminathan (University of Utah, USA)
6:00 pm - 6:20 pmMichael Gale (University of Washington, USA)
"Targeting RIG-I for Antiviral Therapy and Vaccine Adjuvant Against RNA Virus Infection"
6:20 pm - 6:30 pmDiscussion
6:30 pm - 6:50 pmMatthais Gromeier (Duke University Medical Center, USA)
"Cytotoxic and Immunogenic Mechanisms of Oncolytic Poliovirus"
6:50 pm - 7:00 pmDiscussion
7:00 pm - 7:20 pmMatthew Frieman (University of Maryland, USA)
"Pathogenesis and Therapeutic Treatment of the MERS Coronavirus"
7:20 pm - 7:30 pmDiscussion
7:30 pm - 7:40 pmShort Talk Selected from Poster Abstracts
7:40 pm - 7:45 pmDiscussion
7:45 pm - 7:55 pmShort Talk Selected from Poster Abstracts
7:55 pm - 8:00 pmDiscussion
8:00 pmDinner
Friday
7:30 am - 8:30 amBreakfast
9:00 amDeparture
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