Gordon Research Conferences
Meeting Details
Search:
  GO

Glial Biology: Functional Interactions Among Glia and Neurons
Gordon Research Conference

Glial Cells in Health and Disease

Dates

March 1-6, 2015

Location

Four Points Sheraton / Holiday Inn Express
Ventura, CA

Organizers

Chair:
Harald W. Sontheimer

Vice Chair:
Beth A. Stevens

Meeting Description

The overarching goal of the conference is to gain a better understanding of the role of glial cells in brain function, particularly their interactions with each other, with neurons and the brain vasculature. Glia cells are important primary and secondary components in critical physiological processes occurring in the brain. Further, glial cell dysfunction is increasingly being identified as a key factor in several neurodevelopmental and neurological pathologies. The biology of astrocytes, microglia and mylenating glial cells in physiology and pathology will be emphasized in this meeting. Leaders in the field will present cutting edge research and discuss critical gaps in our knowledge. In conjunction with the affiliated Gordon Research Seminar, emerging young scholars will have opportunities to speak or present posters to share new ideas.

The program is divided into nine sessions covering the role of glia in the development of synapses and synaptic circuits, their contribution to blood vessel integrity and cerebral blood flow, their interaction with axons, and the emerging role of glia in neurological disease including neurodevelopmental disorders such as autism and fragile X. Two poster sessions will permit all participants to contribute to these topics.

This meeting is imminently health related by highlighting many instances of identified and proposed glial participation in neurological and neuropsychiatric conditions. The novel research presented at this meeting will serve to advance our understanding of glial cells in both health and disease.

Related Meeting

This GRC was held in conjunction with the "Glial Biology: Functional Interactions Among Glia and Neurons" Gordon Research Seminar (GRS). Refer to the associated GRS program page for more information.

Contributors

Final Meeting Program

Sunday
4:00 pm - 8:00 pmArrival and Check-in
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmGlia and Nervous System Development
Discussion Leader: Nicola Allen (Salk Institute, USA)
7:40 pm - 8:10 pmDavid Rowitch (University of California, San Francisco, USA)
"Heterogeneous Spatial Origins and Functions of Astrocytes in Mammalian CNS"
8:10 pm - 8:20 pmDiscussion
8:20 pm - 8:45 pmCagla Eroglu (Duke University Medical Center, USA)
"Control of Synaptic Connectivity by Astrocytes"
8:45 pm - 8:55 pmDiscussion
8:55 pm - 9:20 pmBeth Stevens (Boston Children's Hospital /Harvard Medical School, USA)
"Immune Mechanisms of Synapse Loss: Lessons from Development"
9:20 pm - 9:30 pmDiscussion
Monday
7:30 am - 8:30 amBreakfast
8:30 amGroup Photo
9:00 am - 12:30 pmGlial and Neurodevelopmental Disorders
Discussion Leader: Wilma Friedman (Rutgers University, USA)
9:00 am - 9:25 amNenad Sestan (Yale University, USA)
"Glia and Human Neurodevelopmental Disorders"
9:25 am - 9:35 amDiscussion
9:35 am - 10:00 amJonathan Kipnis (University of Virginia, USA)
"Microglia: Immunological Cryptographers in Brain Development and Function"
10:00 am - 10:10 amDiscussion
10:10 am - 10:30 amMichelle Olsen (University of Alabama, Birmingham, USA)
"Altered Astrocyte Function in Rett Syndrome"
10:30 am - 10:35 amDiscussion
10:35 am - 11:05 amCoffee Break
11:05 am - 11:30 amVittorio Gallo (Children's National Medical Center, USA)
"Mechanism of Oligodendrocyte Injury and Recovery in the Developing White Matter"
11:30 am - 11:40 amDiscussion
11:40 am - 12:05 pmWenbin Deng (University of California, Davis, USA)
"Stem Cells and Glial Differentiation"
12:05 pm - 12:10 pmDiscussion
12:10 pm - 12:25 pmKelly Monk (Washington University at St. Louis School of Medicine, USA)
"Adhesion G Protein-Coupled Receptors in Myelinating Glial Cell Development and Regeneration"
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmStem Cell Potential of Glia
Discussion Leader: Akiko Nishiyama (University of Connecticut, USA)
7:30 pm - 8:00 pmGong Chen (Pennsylvania State University, USA)
"In Vivo Reprogramming for Brain Repair"
8:00 pm - 8:10 pmDiscussion
8:10 pm - 8:40 pmErik Ullian (University of California, San Franscisco, USA)
"Dysregulated Astrocyte Signaling Revealed Through Human Stem Cell Modeling of Disease"
8:40 pm - 8:50 pmDiscussion
8:50 pm - 9:05 pmSimon Hippenmeyer (Institute of Science and Technology Austria, Austria)
"Programmed Deterministic Genesis of Neurons and Glia in the Neocortex"
9:05 pm - 9:10 pmDiscussion
9:10 pm - 9:25 pmTroy Ghashghaei (North Carolina College of Veterinary Medicine, USA)
"Clonal Analysis of Neurogenesis-to-Gliogenesis Switch in the Developing Cortex"
9:25 pm - 9:30 pmDiscussion
Tuesday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmGlia and Neurodegenerative Diseases
Discussion Leader: Byron Ford (Morehouse School of Medicine, USA)
9:00 am - 9:25 amJeffrey Rothstein (Johns Hopkins Brain Science Insititute, USA)
"Oligodendroglial Degeneration in Neurodegeneration, Maybe a Cell Autonomous Process"
9:25 am - 9:35 amDiscussion
9:35 am - 10:00 amJoseph El Khoury (Massachusetts General Hospital, USA)
"Molecular Profiling of the Neuroimmune System in Aging and Neurodegeneration"
10:00 am - 10:10 amDiscussion
10:10 am - 10:30 amAyodeji Asuni (Lundbeck Pharma A/S, Denmark)
"Astrocytic Signature in the Prion Disease Brain"
10:30 am - 10:35 amDiscussion
10:35 am - 11:05 amCoffee Break
11:05 am - 11:30 amBaljit Khakh (University of California, Los Angeles, USA)
"Correlative and Causative Astrocyte Dysfunctions in Huntington's Disease Model Mice"
11:30 am - 11:35 amDiscussion
11:35 am - 11:55 amMichelle Gray (University of Alabama, Birmingham, USA)
"Huntington's Disease and Astrocytes: An Analysis in BACHD mice."
11:55 am - 12:00 pmDiscussion
12:00 pm - 12:25 pmBrian MacVicar (University of British Columbia, Canada)
"Synaptic Sensing and Modulation by Microglia: A Role in Neurodegeneration?"
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmModel Organisms to Study Glia
Discussion Leader: Vladimir Parpura (University of Alabama, USA)
7:30 pm - 7:55 pmWilliam Talbot (Stanford University, USA)
"Glial Development and Myelination in Zebrafish"
7:55 pm - 8:00 pmDiscussion
8:00 pm - 8:25 pmBruce Appel (University of Colorado School of Medicine, USA)
"Imaging and Genetic Analysis of Oligodendrocyte Development in Zebrafish"
8:25 pm - 8:30 pmDiscussion
8:30 pm - 8:55 pmShai Shaham (Rockefeller University, USA)
"Glia Control Receptive Ending Morphology and Function of Sensory Neurons Through Guanylyl Cyclase Signaling and Engulfment."
8:55 pm - 9:00 pmDiscussion
9:00 pm - 9:25 pmMarc Freeman (University of Massachusetts Medical Center, USA)
"Glial Control of Neural Circuit Assembly and Behavior in Drosophila"
9:25 pm - 9:30 pmDiscussion
Wednesday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmGlial Vascular Interactions
Discussion Leader: Eric Newman (University of Minnesota, USA)
9:00 am - 9:25 amBerislav Zlokovic (Keck School of Medicine of USC, USA)
"The Role of Microvessels in Neurodegeneration"
9:25 am - 9:35 amDiscussion
9:35 am - 10:00 amCostantino Iadecola (Weill Cornell Medical College, USA)
"Role of Glia and Innate Immunity in Neurovascular Dysfunction: Implication for Cognitive Health"
10:00 am - 10:10 amDiscussion
10:10 am - 10:30 amKaterina Akassoglou (University of California, San Francisco, USA)
"Vascular-Derived Factors as Activators and Selective Targets of CNS Innate Immunity"
10:30 am - 10:40 amDiscussion
10:40 am - 11:10 amCoffee Break
11:10 am - 11:30 amAnna Devor (University of California, San Diego, USA)
"Reexamining the Astrocytic Role in Neurovascular Communication and Hemodynamics"
11:30 am - 11:40 amDiscussion
11:40 am - 12:00 pmJessica Filosa (Georgia Regents University, USA)
"Astrocyte Contribution to Hemodynamic-Induced Vascular Responses"
12:00 pm - 12:10 pmDiscussion
12:10 pm - 12:25 pmAnusha Mishra (University College London, United Kingdom)
"Role of Astrocytes in Neurovascular Coupling at the Capillary Level"
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pmGlial Axonal Interactions
Discussion Leader: Bruce Ransom (University of Washington School of Medicine, USA)
7:30 pm - 7:55 pmPeter Stys (University of Calgary, Canada)
"The Axo-Myelinic Synapse: Implications for Physiology and Disease"
7:55 pm - 8:00 pmDiscussion
8:00 pm - 8:25 pmDwight Bergles (Johns Hopkins University School of Medicine, USA)
"Oligodendrocyte Dynamics in the Adult Brain"
8:25 pm - 8:30 pmDiscussion
8:30 pm - 8:55 pmPatrizia Casaccia (Mount Sinai School of Medicine, USA)
"Translational Approaches to Axonal Damage in Demyelinating Disorders"
8:55 pm - 9:00 pmDiscussion
9:00 pm - 9:25 pmKlaus-Armin Nave (Max Planck Institute for Experimental Medicine, Germany)
"Oligodendroglial NMDA Receptor Signaling and Axonal Energy Metabolism"
9:25 pm - 9:30 pmDiscussion
Thursday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmMicroglia in Health and Disease
Discussion Leader: Monica Carson (University of California, Riverside, USA)
9:00 am - 9:25 amWenbiao Gan (Skirball Institute of Biomolecular Medicine, USA)
"Microglia Promote Learning-Dependent Synapse Formation Through Brain-Derived Neurotrophic Factor"
9:25 am - 9:35 amDiscussion
9:35 am - 10:05 amDavid Attwell (University College London, United Kingdom)
"An Ion Channel Regulating Microglial Surveillance of the Brain Parenchyma"
10:05 am - 10:15 amDiscussion
10:15 am - 10:45 amCoffee Break
10:45 am - 11:10 amMargaret McCarthy (University of Maryland, USA)
"Microglia: Sculptors of Brain Sex Differences"
11:10 am - 11:20 amDiscussion
11:20 am - 11:45 amLong-Jun Wu (Rutgers University, USA)
"Microglia-Neuron Communication in Epilepsy"
11:45 am - 11:55 amDiscussion
11:55 am - 12:20 pmHelmut Kettenmann (Max Delbruck Center for Molecular Medicine, Germany)
"How Microglia Promote Glioma Growth"
12:20 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmContribution of Glia to Neuronal Networks In Vivo
Discussion Leader: Sergei Kirov (Medical College of Georgia / Georgia Regents University, USA)
7:30 pm - 8:00 pmJames Schummers (Max Plank Florida Institute for Neuroscience, USA)
"Functional Organization of Astrocytes in Visual Cortex"
8:00 pm - 8:10 pmDiscussion
8:10 pm - 8:40 pmMriganka Sur (Massachusetts Institute of Technology, USA)
"Role of Calcium Signaling and Glutamate Transporters in Visual Cortex Circuits In Vivo"
8:40 pm - 8:50 pmDiscussion
8:50 pm - 9:20 pmMaiken Nedergaard (University of Rochester Medical Center, USA)
"State Dependent Changes in Astrocytic Function"
9:20 pm - 9:30 pmDiscussion
Friday
7:30 am - 8:30 amBreakfast
9:00 amDeparture

Research reported in this publication was supported by the national Institute of Neurological Disorders and Stroke of the National Institutes of Health under award number 1R13NS092101. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
© 2017 Gordon Research Conferences Search | Contact | Terms of Use | Privacy Policy | Follow us: Facebook Twitter