Find a Conference
Alert - GRC ATTENDEES HAVE BEEN TARGETED BY PHISHING ATTEMPTS DESIGNED TO COLLECT PAYMENT FOR REGISTRATION OR LODGING. PLEASE CLICK HERE FOR MORE DETAILS.

Glycolipid and Sphingolipid Biology

Gordon Research Conference

January 11 - 16, 1998
Chair Sarah Spiegel
Vice Chair Guido Tettamanti
Four Points Sheraton / Holiday Inn Express
1050 Schooner Drive
Ventura, California, United States
 Venue and Travel Information

Conference Program

Sunday Evening 7:30-9:30 PM

Membrane Dynamics and Organization of Glyco(sphingo)lipids.

Discussion leaders: Dr. Sen-itiroh Hakomori and Dr. Richard Anderson
  • Dr. Sen-itiroh Hakomori: Glycosphingolipid Microdomain in Cell Adhesions, Coupled with Signaling
  • Dr. Richard Anderson: The Caveolae Membrane System
  • Dr. Sandro Sonnino: Relationships Between the Chemical and Physico-Chemical Properties of Gangliosides and the Formation of Ganglioside-Enriched Membrane Domains
  • Dr.Yukaka Sanai: Association of Src-Family Tyrosine Kinase Lyn with Gangloside GD3 in Rat Brain
  • Dr. Deborah Brown: Organization of Sphingolipids, Cholesterol, and Proteins in Detergent-Resistant Membrane Domains

Monday Morning 8:30-12:30 AM

Trafficking, Transport, Sorting, and Subcellular Localization of Glyco(sphingo)lipids.

Discussion leaders: Dr. Guido Tettamanti and Dr. Richard Pagano
  • Dr. Guido Tettamanti: Introduction
  • Dr. Richard Pagano: Intracellular Transport and Metabolism of Sphingolipid Analogs
  • Dr. Gerrit van Meer: Glycosphingolipid Sorting in Epithelial Cells, Roles for Membrane Domains and Multidrug Transporters
  • Dr. Yoshio Hirabayashi: Biological Function of Glycolipids: Lessons from Glycolipid-Deficient Mutants
  • Dr. William Young: Soluble Glycosyltransferases
  • Dr. Laura Riboni: Sphingolipid Metabolites in Neural Growth and Differentiation
  • Dr. Tony Futerman: Regulatory Roles for Glycolipids and Sphingolipids in Neuronal Growth

Poster Presentations: 4:00 - 6:00

Discussion leader: Dr. Donald Marcus
  • Dr. Erich Gulbins: Function of the Acidic Sphingomyelinase in Cellular Signaling and Internalization Processes

Monday Evening 7:30-9:30 PM

Enzymes, Cofactors and Genes Controlling Glyco(sphingo)lipid Metabolism.

Discussion leaders: Dr. Konrad Sandhoff and Dr. Shimon Gatt
  • Dr. Konrad Sandhoff: Glycolipid Enzymology at Membrane Surface
  • Dr. Shimon Gatt: Application of Fluorescent Sphingolipids to the Study of Normal and Pathological Metabolism
  • Dr. Wendy Campana: Prosaposin and Prosaptides: Novel Neurotrophic and Myelinotrophic Factors
  • Dr. Masaki Saito: Molecular Cloning and Characterization of Human Ganglioside GM3 Synthase (Sialyltransferase-l: SAT-1)
  • Dr. Robert Yu: Regulation of Ganglioside Biosynthesis

Tuesday Morning 8:30-12:30 AM

Gene Targeting Approaches to Glyco(sphingo)lipid Biology.

Discussion leaders: Dr. Kunihiko Suzuki and Dr. Wilhelm Stoffel
  • Dr. Kunihiko Suzuki: Introduction
  • Dr. Wilhelm Stoffel: Glycosphingolipids, Pacemakers of a New Approach to Molecular Membrane Biology
  • Dr. Richard Proia: Genetic Manipulaffon of Ganglioside Synthesis and Degradation Pathways: Implications for Function and Therapeutics
  • Dr. Edward Schuchman: New Insights into Acid Sphingomyelinases and Acid Ceramidase: Lessons from Knock-Out Mice and Other Model Systems
  • Dr. Koichi Furakawa: Genetic Modification of Glycosphingolipids in Experimental Animals
  • Dr. Hong Liu: Identification of Genes Associated with Neuro2a Differentiation Induced by the Expression of GD3 Synthase
  • Dr. Jin-ichi Inokuchi: A New Approach for Improvement of Synaptic Function and Memory Deficits by Up-regulating Ganglioside Biosynthesis with L-threo-PDMP

Poster Presentations: 4:00 - 6:00

Discussion leader: Dr. Subhash Basu
  • Dr. Masaru Taniguchi: Recognition of Glycolipids by NKT Cells

Tuesday Evening 7:30-9:30 PM

Medical and Immunotherapeutic Aspects of Glyco(sphingo)lipids.

Discussion leaders: Dr. Alfred Merrill and Dr. Stephan Ladisch
  • Dr. Alfred Merrill: Sphingolipids in the Prevention and Treatment of Cancer
  • Dr. Stephan Ladisch: Tumor Ganglioside Shedding: Biological Consequences and Therapeutic Strategies
  • Dr. Philip Livingston: Ganglioside Vaccines Against Cancer: From the Laboratory to Phase III Clinical Trials
  • Dr. Takao Taki: Glyco-Replica Peptides which Mimic Functional Roles in Cell Adhesion
  • Dr. Pam Fredman: The Potential Role of Sulfatide in Immunological Disease Processes

Wednesday Morning 8:30-12:30 AM

Sphingolipids Metabolites: Regulation of Cell Growth, Stress and Apoptosis.

Discussion leaders: Dr. Yussuf Hannun and Dr. Sarah Spiegel
  • Dr. Yussuf Hannun: Ceramide and the Eukaryotic Stress Response
  • Dr. Sarah Spiegel: Dual Functions of Sphingosine 1-Phosphate
  • Dr. Lina Obeid: Sphingolipids as Mediators of Cell Cycle Arrest, Cellular Senescence, and Apoptosis
  • Dr. Thierry Levade: Role of Sphingomyelin Hydrolysis in Regulation of Cell Growth
  • Dr. Gerhild van Echten: Organization and Regulation of Sphingolipid Biosynthesis: Studies with Synthetic Sphingolipid Analogs
  • Dr. Jonathan Tilly: Lipid-Signaling Pathways in Chemotherapy-Induced Germ Cell Apoptosis
  • Dr. Yasuyuki Igarashi: Sphingosine 1-Phosphate as an Intercellular Messenger Released from Activated Platelets, Conceivably Playing a Variety of Physiological and Pathophysiological Roles in Blood Vessels

Poster Presentations: 4:00 - 6:00

Discussion leader: Dr. Roger Laine

Wednesday Evening 7:30-9:30 PM

Sphingolipid Metabolism in Yeast and Mammalian Cells.

Discussion leaders: Dr. Robert Dickson and Dr. Suzanne Mandala
  • Dr. Robert Dickson: The Role of Sphingolipid Signaling During Saccharomyces Cerevisiae Stress Responses
  • Dr. Suzanne Mandala: Sphingolipid Metabolites and Stress Response in Yeast
  • Dr. James Shayman: Characterization of 1-O-Ceramide Synthase, A Novel Phospholipase A2
  • Dr. Manjo Basu: Hydrophobic Nature of the Mammalian Ceramide Glycanases
  • Dr. Julie Saba: Isolation of Sphingosine Phosphate Lyase from Saccharomyces Cerevisiae

Thursday Morning 8:30-12:30 AM

Transmembrane Signaling I: Sphingolipids Metabolites.

Discussion leaders: Dr. Richard Kolesnick and Glyn Dawson
  • Dr. Richard Kolesnick: Endothelial Apoptosis and Disease
  • Dr. Glyn Dawson: Regulation of Ceramide Catabolism and Apoptosis
  • Dr. Guido Kroemer: Cerarnide-Induced Apoptosis: Implication of Mitochondria
  • Dr. Jorge Moscat: Control of Proliferation and Survivat Through the Atypicat PKC Pathways
  • Dr. Martin Kronke: Activation of Acidic and Neutrat Sphingomyelinases by TNF Receptor-Associated Proteins
  • Dr. Josef Pfeilschifter: Identification of Ceramide Targets
  • Dr. Roberto Testi: Lipid and Glycolipid Mediators of Fas-Induced Apoptosis

    Thursday Evening 7:30-9:30 PM

    Glycolipid Signaling, Recognition and Adhesion.

    Discussion leaders: Dr. Yoshitaka Nagai and Dr. Robert Ledeen
    • Dr. Yoshitaka Nagai: Introduction
    • Dr. Robert Ledeen: Nuclear Gangliosides and Neuronat Differentiation
    • Dr. Clifford Lingwood: Globotriaosyl Ceramide Provides a Conduit from the Cell Surface to the Nucleus
    • Dr. Ronald Schnaar: Ganglioside Recognition by Myelin-Associated Glycoprotein

    • Contributors

    Sincere thanks are extended to the following for their generous support:

    Mizutani Foundation
    Mitsubishi Kasei Corporation
    Sankyo Company, Inc.
    FIDIA Company
    Agmen, Inc.
    Hoffmann-La Roche
    Merck Research Laboratories
    National Science Foundation
    Glaxo Wellcome, Inc.

    Conference Links

    Conference History
    Additional Fee Info

    Carbohydrates
    June 15 - 20, 2025
    Lysosomal Diseases
    March 2 - 7, 2025


    Contact Us

    MyGRC Account
    Check your application status, complete your registration, update your poster, change your rooming preference, make a bus reservation, print an invitation letter, print a receipt (which includes verification that you are presenting a poster) or print an invoice by logging into your account.

    GRC Venues
    Everything you need to know, to plan your trip.

    FAQs
    Instant answers to common questions.

    Tell us how we can help

    Call us and leave a detailed message at: 401-783-4011

    *This voicemail is only checked once daily. Due to high volume of requests during the conference season, responses may be delayed.

    You have no notifications