Conference Description
The processing and transport of proteins and lipids in the secretory pathway (and in non-traditional secretory pathways) are linked to a broad array of physiological processes and disease mechanisms, including diabetes, Alzheimer's Disease, dyslipidemia, atherosclerosis, inflammation, and immunological diseases. Within this diversity, there are common themes, including protein misfolding and the signaling pathways it evokes, autophagy, nutrient sensing, and intercellular communication. Among the topics included in this conference are: mechanisms of nutrient sensing linked to protein secretion, protein modification and splicing in the secretory pathway, proteases and Alzheimer's Disease, prohormone convertases, pathways of entry and pathways of assembly and secretion of COVID-19. There will be speakers who will focus on technological advances in visualization of the secretory pathway in living cells. This conference is organized to maximize the participation of trainees with daily poster sessions, slots reserved for poster presenters to speak in the general sessions, and rapid-fire "poster previews" from all poster presenters. By the end of the week, nearly all participants will have met one another and will take home valuable feedback from their discussions.
The topics, speakers, and discussion leaders for the conference sessions are displayed below. The conference chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by March 17, 2022. Please check back for updates.
Protein Folding in the Secretory Pathway
Discussion Leaders
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Regina Fluhrer (University of Augsburg, Germany)
Speakers
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Jason Gestwicki (University of California, San Francisco, USA)
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Carmine Settembre (Telethon Foundation, Italy)
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Feroz Papa (University of California, San Francisco, USA)
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Feyza Engin (University of Wisconsin-Madison, USA)
Glycosylation and Phosphorylation in the Secretory Pathway
Discussion Leaders
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Melkam Kebede (The University of Sydney, Australia)
Speakers
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Hudson Freeze (Sanford Burnham Health Research Center, USA)
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Heather Flanagan-Steet (Greenwood Genetic Center, USA)
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Kelly Ten Hagen (NIH, USA)
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Michael Boyce (Duke University School of Medicine, USA)
Nutrient Sensing, Ion Channels and Vesicle Trafficking
Discussion Leaders
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Peter Arvan (University of Michigan Medical School, USA)
Speakers
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Matthew Merrins (University of Wisconsin-Madison, USA)
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Debbie Thurmond (City of Hope, USA)
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Samuel Stephens (University of Iowa, USA)
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Melkam Kebede (The University of Sydney, Australia)
Protein Aggregation, Proteostasis and Autophagy
Discussion Leaders
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Feyza Engin (University of Wisconsin-Madison, USA)
Speakers
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Mondira Kundu (St. Jude Children's Research Hospital, USA)
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Luigi Puglielli (University of Wisconsin-Madison, USA)
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Judith Frydman (Stanford University, USA)
COVID-19 Entry Into the Cell and Assembly in the Secretory Pathway
Discussion Leaders
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Carmine Settembre (Telethon Foundation, Italy)
Speakers
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Gary Whittaker (Cornell University, USA)
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Nihal Altan-Bonnet (National Institutes of Health, USA)
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Hector Aguilar-Carreno (Cornell University, USA)
Visualizing the Secretory Pathway
Discussion Leaders
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Julia von Blume (Yale University, USA)
Speakers
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Ana Paula Arruda (Harvard TH Chan School of Public Health, USA)
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Anjon Audhya (University of Wisconsin-Madison, USA)
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Michele Solimena (TU Dresden, Germany)
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Joerg Bewersdorf (Yale University, USA)
Lipid Transport Through the Secretory Pathway
Discussion Leaders
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Michele Solimena (TU Dresden, Germany)
Speakers
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Anant Menon (Weill Cornell Medicine, USA)
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Russell Debose-Boyd (University of Texas Southwestern Medical Center, USA)
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Thomas Melia (Yale University, USA)
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Elina Ikonen (University of Helsinki, Finland)
Proteolysis in the Secretory Pathway
Discussion Leaders
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Nabil Seidah (University of Montreal, Canada)
Speakers
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Thomas Delong (University of Colorado Anschutz Medical Campus, USA)
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Annik Prat (Clinical Research Institute of Montreal, Canada)
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Regina Fluhrer (University of Augsburg, Germany)
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Stefan Lichtenthaler (German Center for Neurodegenerative Diseases (DZNE), Germany)
Exosomes
Discussion Leaders
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Anjon Audhya (University of Wisconsin-Madison, USA)
Speakers
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Carmella Evans-Molina (Indiana University School of Medicine, USA)
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Philipp Scherer (University of Texas Southwestern Medical Center, USA)
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Wei Guo (University of Pennsylvania, USA)
The GRC Power Hour™
Organizers:
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Julia von Blume (Yale University, USA)
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Iris Lindberg (University of Maryland School of Medicine, USA)
