Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Chemical Editing of Proteoglycan Architecture
Discussion Leaders: Lorna Milne (School of Pharmacy, The University of Nottingham, United Kingdom) and Deepsing Syangtan (MIT, United States)
3:45 pm - 4:15 pm
Mia Huang (Scripps Research, United States)
"Chemical Editing of Proteoglycan Architecture"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Proteoglycan Regulation in Health and Disease
Discussion Leaders: Karina Dias Teixeira (University of Virginia, United States) and Meg Critcher (Scripps Research, United States)
7:30 pm - 7:45 pm
Kathryn Malpas (University of Manchester, United Kingdom)
"Characterisation of the Interactions of Recombinany Murine Chitinase-Like Proteins with Glycosaminoglycans"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Amulya Sreekumar (University of Pennsylvania, United States)
"Heparan Sulfate Proteoglycans Promote Residual Tumor Cell Survival and Breast Cancer Recurrence"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Fabian Gude (WWU Münster / UKM Institute of physiological chemistry and pathobiochemistry, Germany)
"Bivalent Heparan Sulfate Interactions Determine Hedgehog Morphogen Gradient Robustness and Range: A General Mechanism for Extracellular Protein Distribution?"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Anna Whitehead (Louisiana State University Health Sciences Center- New Orleans, United States)
"Myeloid Sulf Deletion and Immune Dysfunction in Multiple Sulfatase Deficiency"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Amrita Basu (University of Georgia, United States)
"TFCP2 is a Novel Transcriptional Regulator of Growth Factor Binding to 6-O Sulfated Heparan Sulfate"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Ryan Sullivan (University of Colorado, United States)
"The Impact of Aging on Sepsis-Related Endothelial Glycocalyx Degradation"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Structural Analysis, Technologies and Emerging Therapeutics
Discussion Leaders: Kimberly Alonge (University of Washington, United States) and Christophe Langouet-Astrie (University of Colorado Denver, Anshutz Medical Campus, United States)
9:00 am - 9:15 am
Margaret Downs (Boston University, United States)
"Alterations to the Extracellular Matrix of Anterior Cerebral Artery in Alzheimer’s Disease"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Max Urbanczyk (University Hospital Tübingen, Germany)
"Decorin Improves Pancreatic ß-cell Function and Regulates ECM Expression in vitro"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Anna Gray (University of Manchester, United Kingdom)
"High Resolution Intravital Imaging to examine the mouse endothelial glycocalyx"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Samreen Jatana (Cleveland Clinic Foundation, United States)
"Protective Effect of 35 kDa Molecular Weight Hyaluronan in Maintenance of the Epithelial Barrier in Colonic Organoids under Hyperglycemic Stress"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Zhangjie Wang (University of North Carolina at Chapel Hill, United States)
"Analysis of 3-O-sulfated Heparan Sulfate in Neurodegenerative Disease Using Isotopically Labeled Oligosaccharide Calibrants"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Jake Valeri (Department of Psychiatry -- University of Mississippi Medical Center, United States)
"Extracellular Matrix Abnormalities in Substance Use and Major Depressive Disorders"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Navigating Scientific Careers in Academia and Industry
Discussion Leaders: Mia Huang (Scripps Research, United States)
1:30 pm - 2:30 pm
Panel Discussion
Navigating Scientific Careers in Academia and Industry
Alyssa Panitch (Georgia Tech and Emory, United States)
Joseph Hippensteel (University of Colorado Anschutz Medical Campus, United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes
