|2:00 pm - 5:00 pm||Arrival and Check-in|
|3:30 pm - 3:45 pm||Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair|
|3:45 pm - 4:30 pm||Keynote Session: From Stem Cells to Red Cells|
|Discussion Leader: Vikram Paralkar (University of Pennsylvania, USA)|
|3:45 pm - 4:25 pm||Janis Abkowitz (University of Washington, USA)|
"The Paths from Erythroid Progenitor to Red Cell and Fellow to Professor"
|4:25 pm - 4:30 pm||Discussion|
|4:30 pm - 6:00 pm||Poster Session|
|7:30 pm - 9:30 pm||Genetics, Epigenetics and Erythropoiesis|
|Discussion Leaders: Shuming Sun (New York Blood Center, USA) and Elizabeth Traxler (University of Pennsylvania, USA)|
|7:30 pm - 7:45 pm||Ivan Krivega (National Institute of Diabetes and Digestive and Kidney Diseases, NIH, USA)|
"Inhibition of G9a Methyltransferase Stimulates Fetal Hemoglobin Production by Facilitating LCR/Globin Looping"
|7:45 pm - 7:50 pm||Discussion|
|7:50 pm - 8:05 pm||Xin Liu (University of Texas Southwestern Medical Center, USA)|
"Combinatorial Regulation of Enhancer Repertoires Controls Erythroid Lineage and Developmental Stage-Specific Transcription"
|8:05 pm - 8:10 pm||Discussion|
|8:10 pm - 8:25 pm||Maria Suciu (Weatherall Institute for Molecular Medicine, University of Oxford, United Kingdom)|
"Analysis at High Resolution of Transcription Factor Binding Sites at Cis Regulatory Elements During Development and Differentiation"
|8:25 pm - 8:30 pm||Discussion|
|8:30 pm - 8:45 pm||Yung Hwang (University of Massachusetts Medical School, USA)|
"Reprograming of S Phase at the Switch from Self-Renewal to Differentiation in Erythroid CFUe Progenitors Is Regulated by the Cyclin-Dependent-Kinase Inhibitor (CDKI) p57KIP2"
|8:45 pm - 8:50 pm||Discussion|
|8:50 pm - 9:05 pm||Raymond Liang (Icahn School of Medicine at Mount Sinai, USA)|
"Essential FOXO3 Functions in Polarity, Enucleation and Terminal Maturation of Red Blood Cells"
|9:05 pm - 9:10 pm||Discussion|
|9:10 pm - 9:25 pm||Satish Nandakumar (Boston Children's Hospital, USA)|
"Systematic Genetic Dissection of Common Human Variation in Red Blood Cell Traits"
|9:25 pm - 9:30 pm||Discussion|
|7:30 am - 8:30 am||Breakfast|
|9:00 am - 11:00 am||Membranes and Red Cell Disorders|
|Discussion Leaders: Aishwarya Swaminathan (University of Massachusetts Medical School, USA) and Elina Ovchynnikova (Sanquin Research, The Netherlands)|
|9:00 am - 9:15 am||Yang Mei (Northwestern University, USA)|
"Mice with Hematopoietic Specific mDia2 Deficiency Develop Ineffective Erythropoiesis Closely Mimicking Congenital Dyserythropoietic Anemia"
|9:15 am - 9:20 am||Discussion|
|9:20 am - 9:35 am||Elizabeth Macari (Boston Children's Hospital, USA)|
"Calmodulin Inhibition Rescues the Effects of Ribosomal Protein Deficiency in Diamond Blackfan Anemia Models"
|9:35 am - 9:40 am||Discussion|
|9:40 am - 9:55 am||Brian Dulmovits (Feinstein Institute for Medical Research, Hofstra North Shore-LIJ School of Medicine, USA)|
"Loss of RASA3 Results in Defective Terminal Erythroid Differentiation"
|9:55 am - 10:00 am||Discussion|
|10:00 am - 10:15 am||Satheesh Chonat (Cincinnati Children's Hospital Medical Center, USA)|
"The Spectrum of Alpha-Spectrin Associated Hereditary Spherocytosis"
|10:15 am - 10:20 am||Discussion|
|10:20 am - 10:35 am||Novalia Pishesha (Whitehead Institute for Biomedical Research / Massachusetts Institute of Technology, USA)|
"Antigen-Decorated Engineered Red Blood Cells as a Novel Immune Tolerance-Inducing Agent"
|10:35 am - 10:40 am||Discussion|
|10:40 am - 10:55 am||Nai-Jia Huang (Whitehead Institute, USA)|
"Engineering Red Cells for Anti-Botulinum Toxin"
|10:55 am - 11:00 am||Discussion|
|11:00 am - 12:30 pm||Poster Session|
|Coffee will be served in the poster area from 11:00 am - 11:30 am|
|1:30 pm - 2:30 pm||Mentorship Component: Career Development|
|Discussion Leader: Bryony Graham (Weatherall Institute of Molecular Medicine, United Kingdom)|
|1:30 pm - 2:05 pm||Gerd Blobel (University of Pennsylvania, USA)|
"Developing a Career as a Scientist"
|2:05 pm - 2:10 pm||Discussion|
|2:10 pm - 2:25 pm||Terry Bishop (National Institute of Diabetes and Digestive and Kidney Diseases, NIH, USA)|
"How to Get an NIH Grant"
|2:25 pm - 2:30 pm||Discussion|
|2:30 pm - 3:00 pm||Evaluation Period|
|Fill in GRS Evaluation Forms|
|3:00 pm||Seminar Concludes|