1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Functional Nucleic Acid Nanoparticles
Nestor Sampedro (Aarhus University, Denmark)
3:45 pm - 4:10 pm
Jaimie Stewart (California Institute of Technology, United States) "Functional Nucleic Acid Nanoparticles"
4:10 pm - 4:15 pm
4:15 pm - 4:25 pm
Samuel Schaffter (National Institute of Standards and Technology, United States) "Cotranscriptionally Encoded RNA Strand Displacement Circuits for Engineering Biology"
4:25 pm - 4:30 pm
4:30 pm - 6:00 pm
6:00 pm - 7:00 pm
7:30 pm - 9:30 pm
Computational, Structural, and Mechanistic Studies of Nucleic Acids
Marco Todisco (HHMI/University of Chicago, United States)
7:30 pm - 7:40 pm
Emanuela Torelli (Newcastle University, United Kingdom) "Co-transcriptionally Folded RNA Origami and DNA Stack Memory as Potential Interfaces Able to Operate
7:40 pm - 7:45 pm
7:45 pm - 7:55 pm
Lewis Rolband (University of North Carolina at Charlotte, United States) "SAXS for NANPs: Advancing the Structural Characterization of Nucleic Acid Nanoparticles Through Small-angle X-ray Scattering"
7:55 pm - 8:00 pm
8:00 pm - 8:10 pm
Byunghwa Kang (Pohang University of Science and Technology (POSTECH), South Korea) "In Vitro Evolution with Rationally-Designed RNA Library: Generation of Smallest Trans-Acting Ligase Ribozyme that Enables RNA Concatenation"
8:10 pm - 8:15 pm
8:15 pm - 8:25 pm
Kai Sheng (The Scripps Research Institute, United States) "Unsupervised Voxel-based Segmentation reveals a Landscape of Bacterial Ribosome Large Subunit Early Assembly"
8:25 pm - 8:30 pm
8:30 pm - 8:40 pm
Olivia Zou (California Institute of Technology, United States) "Engineering DNA Liquids for Macroscopic Separation of Biomolecules"
8:40 pm - 8:45 pm
8:45 pm - 8:55 pm
David Bushhouse (Northwestern University, United States) "Expression Platform Features Tune Functional Characteristics of the
Clostridium beijerinckii ZTP Riboswitch"
8:55 pm - 9:00 pm
9:00 pm - 9:10 pm
Edric Choi (Northwestern University, United States) "Deducing RNA Structure and Dynamics from Quantitative Analysis of Chemical Probing Reactivities"
9:10 pm - 9:15 pm
9:15 pm - 9:25 pm
Everett Kengmana (Johns Hopkins University, United States) "Engineering DNA Droplet-Droplet Signaling via Transcription"
9:25 pm - 9:30 pm
7:30 am - 8:30 am
9:00 am - 11:00 am
RNA Nanomaterials in Therapy and Medicine
Aleksandar Radakovic (Harvard University, United States)
9:00 am - 9:10 am
Michael Dore (Northwestern University, United States) "mRNA and Peptide Amphiphile Nanofibers"
9:10 am - 9:15 am
9:15 am - 9:25 am
Grant Knappe (Massachusetts Institute of Technology, United States) "Functionalizing Nucleic Acid Nanoparticles for the Delivery of Nucleic Acid Therapeutics"
9:25 am - 9:30 am
9:30 am - 9:40 am
Vincent Clark (Johns Hopkins University, United States) "Development of an Aptamer Based Sensor for Point of Care Monitoring of Antiretroviral Therapy"
9:40 am - 9:45 am
9:45 am - 9:55 am
B.J. (Byungji) Kim (MIT, United States) "Role of the Type 1 Interferon Response in Humoral Immunity Elicited by Self-Replicating RNA Vaccines"
9:55 am - 10:00 am
10:00 am - 10:10 am
Anna Romanov (MIT Biological Engineering, United States) "A DNA-scaffolded Vaccine Platform for Programmable Presentation of Engineered HIV Immunogens"
10:10 am - 10:15 am
10:15 am - 10:25 am
Emily Helm (Johns Hopkins University, United States) "Engineering Reusable Synthetic RNA Strand Displacement Circuits"
10:25 am - 10:30 am
10:30 am - 10:40 am
Matthew Allan (Massachusetts Institute of Technology, United States) "3D RNA-Scaffolded Wireframe Origami"
10:40 am - 10:45 am
10:45 am - 10:55 am
Lan Mi (University of Massachusetts, Amherst, United States) "Genetically Encoded Fluorogenic RNA-based Bioluminescence Resonance Energy Transfer (BRET) Sensors for Cellular Imaging and Target Detection"
10:55 am - 11:00 am
11:00 am - 12:30 pm
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
1:30 pm - 2:30 pm
Mentorship Component: The Next Generation of RNA Therapeutics
Laura Hertz (Northwestern University, United States)
1:30 pm - 2:30 pm
The Next Generation of RNA Therapeutics
Emil Khisamutdinov (Ball State University, United States)
Scott Tenenbaum (SUNY Polytechnic Institute, United States)
Mira Moufarrej (The Column Group, United States)
Lorena Parlea (GSK VACCINES, United States)
2:30 pm - 3:00 pm
Complete the GRS Evaluation Forms; Election of Future Chair(s)