Sunday
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4:00 pm - 8:00 pm |
Arrival and Check-in
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6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 7:40 pm |
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
|
7:40 pm - 9:30 pm |
Microbial Molecular Machines
Discussion Leader: Kelly Hughes (University of Utah, USA)
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7:40 pm - 7:45 pm |
Introduction by Discussion Leader
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7:45 pm - 8:05 pm |
Ariane Briegel (Leiden University, The Netherlands)
"Insights into Chemotaxis of Non-Model Organisms by Cryo-Electron Tomography"
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8:05 pm - 8:10 pm |
Discussion
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8:10 pm - 8:30 pm |
Edward Egelman (University of Virginia, USA)
"Cryo-EM of Bacterial and Archaeal Polymers at Near-Atomic Resolution Yields Many Surprises"
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8:30 pm - 8:35 pm |
Discussion
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8:35 pm - 8:55 pm |
Katsumi Imada (Osaka University, Japan)
"Structure of the Growing Tip of the Flagellar Filament Using Cryo-EM and X-Ray Crystallography"
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8:55 pm - 9:00 pm |
Discussion
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9:00 pm - 9:20 pm |
Lotte Sogaard-Andersen (Max Planck Institute for Terrestrial Microbiology, Germany)
"Regulation of Type IV Pili-Dependent Motility in Myxococcus xanthus"
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9:20 pm - 9:25 pm |
Discussion
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9:25 pm - 9:30 pm |
General Discussion
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Monday
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7:30 am - 8:30 am |
Breakfast
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9:00 am - 12:30 pm |
Nucleotide-Mediated Signaling
Discussion Leader: Michael Laub (Massachusetts Institute of Technology / Howard Hughes Medical Institute, USA)
|
9:00 am - 9:05 am |
Introduction by Discussion Leader
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9:05 am - 9:25 am |
Ming Hammond (University of Utah, USA)
"Evolution of Divergent Cyclic Dinucleotide Signaling Pathways"
|
9:25 am - 9:30 am |
Discussion
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9:30 am - 9:50 am |
Urs Jenal (Biozentrum, University of Basel, Switzerland)
"Second Messenger-Based Signalling in Bacterial Growth and Behavior"
|
9:50 am - 9:55 am |
Discussion
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9:55 am - 10:15 am |
John Mekalanos (Harvard Medical School, USA)
"Diverse Nucleotide Signals in Bacteria"
|
10:15 am - 10:20 am |
Discussion
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10:20 am - 10:50 am |
Coffee Break
|
10:50 am - 11:00 am |
Rebecca Lau (University of California, San Diego, USA)
"A Novel Cyclic Trinucleotide Signaling Pathway Provides Bacteriophage Immunity in Bacteria"
|
11:00 am - 11:05 am |
Discussion
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11:05 am - 11:25 am |
Chris Waters (Michigan State University, USA)
"A Symphony of Cyclic Di-Nucleotides"
|
11:25 am - 11:30 am |
Discussion
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11:30 am - 11:50 am |
Emily Weinert (The Pennsylvania State University, USA)
"Investigating 2',3'-cNMPs in Bacteria: From Metabolism to Cellular Roles"
|
11:50 am - 11:55 am |
Discussion
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11:55 am - 12:05 pm |
Daisuke Nakane (Gakushuin University, Japan)
"Second Messengers Mediate Directional Switching of Phototaxis in Rod-Shaped Cyanobacteria"
|
12:05 pm - 12:10 pm |
Discussion
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12:10 pm - 12:20 pm |
Mark Aronson (Boston University, USA)
"Identifying Biofilm Formation Decision Algorithms: Deciphering the Role of Cyclic di-GMP in the B. subtilis Motility Switch"
|
12:20 pm - 12:25 pm |
Discussion
|
12:25 pm - 12:30 pm |
General Discussion
|
12:30 pm - 1:30 pm |
Lunch
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1:30 pm - 4:00 pm |
Free Time
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3:00 pm - 4:00 pm |
The GRC Power Hour™
The GRC Power Hour™ is designed to address challenges women face in science and issues of diversity and inclusion. The program supports the professional growth of all members of our communities by providing an open forum for discussion and mentoring.
Organizer: Karen Ottemann (University of California, Santa Cruz, USA)
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4:00 pm - 6:00 pm |
Poster Session
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6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 9:30 pm |
Metabolic Control of Physiological Processes
Discussion Leader: Monica Gerth (Victoria University of Wellington, New Zealand)
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7:30 pm - 7:35 pm |
Introduction by Discussion Leader
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7:35 pm - 7:55 pm |
Susan Golden (University of California, San Diego, USA)
"Circadian Control of Gene Expression In Vivo and In Vitro"
|
7:55 pm - 8:00 pm |
Discussion
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8:00 pm - 8:20 pm |
Petra Levin (Washington University in St. Louis, USA)
"Shaping the Cell from the Outside In"
|
8:20 pm - 8:25 pm |
Discussion
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8:25 pm - 8:45 pm |
Gisela Storz (National Institute of Child Health and Human Development, NIH, USA)
"Complexity and Redundancy in Regulatory RNA Networks"
|
8:45 pm - 8:50 pm |
Discussion
|
8:50 pm - 9:10 pm |
Alan Wolfe (Loyola University Chicago, USA)
"Signals from Central Metabolism: Bacterial Protein Acetylation"
|
9:10 pm - 9:15 pm |
Discussion
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9:15 pm - 9:25 pm |
Kelsey Barrasso (Tufts University School of Medicine, USA)
"Ethanolamine Modulates the Quorum Sensing Response of V. cholerae as a Source of Signal Interference to CqsR Receptor Kinase Activity"
|
9:25 pm - 9:30 pm |
Discussion
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Tuesday
|
7:30 am - 8:30 am |
Breakfast
|
8:30 am - 9:00 am |
Group Photo
|
9:00 am - 12:30 pm |
Modeling and Motility
Discussion Leader: Thierry Emonet (Yale University, USA)
|
9:00 am - 9:05 am |
Introduction by Discussion Leader
|
9:05 am - 9:25 am |
Judith Armitage (University of Oxford, United Kingdom)
"Dynamics of Rhodobacter Motor Proteins"
|
9:25 am - 9:30 am |
Discussion
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9:30 am - 9:50 am |
Akihiko Ishijima (Graduate School of Frontier Biosciences, Osaka University, Japan)
"The Chemotactic Response and Motor Function of a Bacterial Flagellar Motor in a Single Cell"
|
9:50 am - 9:55 am |
Discussion
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9:55 am - 10:15 am |
Tino Krell (Estación Experimental del Zaidín, CSIC, Spain)
"Differential Recognition of CheR and CheB by C-Terminal Pentapeptides of Chemoreceptors"
|
10:15 am - 10:20 am |
Discussion
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10:20 am - 10:50 am |
Coffee Break
|
10:50 am - 11:00 am |
Matthias Koch (Princeton University, USA)
"Competitive Substrate Binding Coordinates the Two Antagonistic Motors of the Type IV Pilus in P. aeruginosa"
|
11:00 am - 11:05 am |
Discussion
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11:05 am - 11:25 am |
Victor Sourjik (Max Planck Institute for Terrestrial Microbiology, Germany)
"Physiological Importance and Optimal Regulation of Bacterial Chemotaxis"
|
11:25 am - 11:30 am |
Discussion
|
11:30 am - 11:40 am |
Beile Gao (South China Sea Institute of Oceanology, Chinese Academy of Sciences, China)
"A Novel Chemotaxis Signaling Protein in Campylobacter jejuni that Responds to Oxygen Level"
|
11:40 am - 11:45 am |
Discussion
|
11:45 am - 12:05 pm |
Katja Taute (Rowland Institute at Harvard, USA)
"More Is Different: Lessons from High-Throughput 3D Bacterial Tracking"
|
12:05 pm - 12:10 pm |
Discussion
|
12:10 pm - 12:20 pm |
Hannah Walters-Morgan (University of Birmingham, United Kingdom)
"The Sweet Smell of Death"
|
12:20 pm - 12:25 pm |
Discussion
|
12:25 pm - 12:30 pm |
General Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 9:30 pm |
Sensing the Environment
Discussion Leader: Michael Manson (Texas A&M University, USA)
|
7:30 pm - 7:35 pm |
Introduction by Discussion Leader
|
7:35 pm - 7:55 pm |
Igor Jouline (The Ohio State University, USA)
"How Do Novel Bacterial Sensors Emerge?"
|
7:55 pm - 8:00 pm |
Discussion
|
8:00 pm - 8:20 pm |
Michelle Reniere (University of Washington, USA)
"How an Intracellular Bacterial Pathogen Recognizes the Host Cytosol"
|
8:20 pm - 8:25 pm |
Discussion
|
8:25 pm - 8:45 pm |
Kylie Watts (Loma Linda University, USA)
"When One PAS Domain Isn't Enough: Oxygen Sensing by Aer2 Receptors with 1, 2 or 3 PAS-Heme Domains"
|
8:45 pm - 8:50 pm |
Discussion
|
8:50 pm - 9:00 pm |
Rebecca Schomer (University of California, Davis, USA)
"Hybrid Two-Component Systems to Identify Chemoreceptor Function in Pseudomonas putida"
|
9:00 pm - 9:05 pm |
Discussion
|
9:05 pm - 9:25 pm |
Birgit Scharf (Virginia Tech, USA)
"Receptor Repertoire of the Plant Symbiont Sinorhizobium meliloti"
|
9:25 pm - 9:30 pm |
Discussion
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Wednesday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am - 12:30 pm |
Two-Component Signaling Mechanisms
Discussion Leader: Karen Ottemann (University of California, Santa Cruz, USA)
|
9:00 am - 9:05 am |
Introduction by Discussion Leader
|
9:05 am - 9:25 am |
Brian Crane (Cornell University, USA)
"Engineered Two-Component Core Signaling Units Indicate a Constrained Off-State for the CheA Kinase"
|
9:25 am - 9:30 am |
Discussion
|
9:30 am - 9:50 am |
Kevin Gardner (CUNY Advanced Science Research Center, USA)
"Comparative Studies of LOV Signaling Mechanisms and Regulation"
|
9:50 am - 9:55 am |
Discussion
|
9:55 am - 10:05 am |
Felipe Trajtenberg (Institut Pasteur de Montevideo, Uruguay)
"Mechanistic Insights of Phosphoryl-Transfer Reactions in Two-Component Systems"
|
10:05 am - 10:10 am |
Discussion
|
10:10 am - 10:20 am |
Helen Miller (University of Oxford, United Kingdom)
"Tracking Proteins in 3D Within Bacteria"
|
10:20 am - 10:25 am |
Discussion
|
10:25 am - 10:55 am |
Coffee Break
|
10:55 am - 11:15 am |
Linda Kenney (University of Texas Medical Branch, USA)
"Non-Canonical Activation in Two-Component Systems"
|
11:15 am - 11:20 am |
Discussion
|
11:20 am - 11:40 am |
W. Seth Childers (University of Pittsburgh, USA)
"Strategies to Synthetic Regulate and Monitor Bacterial Signaling Networks"
|
11:40 am - 11:45 am |
Discussion
|
11:45 am - 12:05 pm |
Ann Stock (Robert Wood Johnson Medical School, Rutgers University, USA)
"Design Principles in Two-Component Systems"
|
12:05 pm - 12:10 pm |
Discussion
|
12:10 pm - 12:20 pm |
Saumya Saurabh (Stanford University, USA)
"Robust Kinase Regulation by Phase Separation: Implications for Bacterial Signaling in the Wild"
|
12:20 pm - 12:25 pm |
Discussion
|
12:25 pm - 12:30 pm |
General Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:00 pm - 7:30 pm |
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
|
7:30 pm - 9:30 pm |
Growth Control and Antimicrobial Resistance
Discussion Leader: Lynn Connolly (Vir Biotechnology, USA)
|
7:30 pm - 7:35 pm |
Introduction by Discussion Leader
|
7:35 pm - 7:55 pm |
Robert Abramovitch (Michigan State University, USA)
"Small Molecules Targeting Two-Component Regulatory Systems"
|
7:55 pm - 8:00 pm |
Discussion
|
8:00 pm - 8:20 pm |
Erin Carlson (University of Minnesota, USA)
"Global Histidine Kinase Inhibition to Tackle Bacterial Virulence"
|
8:20 pm - 8:25 pm |
Discussion
|
8:25 pm - 8:45 pm |
Dianne Newman (California Institute of Technology, USA)
"Collateral Benefits of Slaying Your Own Demons"
|
8:45 pm - 8:50 pm |
Discussion
|
8:50 pm - 9:10 pm |
Scott Stibitz (Center for Biologics Evaluation and Research, FDA, USA)
"Mechanisms of Regulation of the Bvg-Repressed Genes of Bordetella pertussis"
|
9:10 pm - 9:15 pm |
Discussion
|
9:15 pm - 9:25 pm |
Giancarlo Bruni (University of Colorado Boulder, USA)
"Bactericidal Action of Aminoglycosides Arises from ATPase Induced Dysregulated Membrane Voltage"
|
9:25 pm - 9:30 pm |
Discussion
|
Thursday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am - 12:30 pm |
The Bacterial Cell Envelope
Discussion Leader: Lori Burrows (McMaster University, Canada)
|
9:00 am - 9:05 am |
Introduction by Discussion Leader
|
9:05 am - 9:25 am |
Jean-Francois Collet (UCLouvain, Belgium)
"Unlocking Envelope Mysteries with RcsF, an Outer Membrane Stress Sensor"
|
9:25 am - 9:30 am |
Discussion
|
9:30 am - 9:50 am |
Anna Konovalova (University of Texas Health Science Center at Houston, USA)
"Mechanism of Signal Transduction Across the Bacterial Cell Envelope"
|
9:50 am - 9:55 am |
Discussion
|
9:55 am - 10:15 am |
Susan Lea (University of Oxford, United Kingdom)
"The Structural Biology of Bacterial Secretion Systems"
|
10:15 am - 10:20 am |
Discussion
|
10:20 am - 10:55 am |
Coffee Break
|
10:55 am - 11:05 am |
Hiroyuki Terashima (Nagoya University, Japan)
"Assembly Mechanism of the MS-Ring to Initiate Bacterial Flagellar Biogenesis in Vibrio"
|
11:05 am - 11:10 am |
Discussion
|
11:10 am - 11:30 am |
Jun Liu (Yale School of Medicine, USA)
"High Resolution Visualization of Bacterial Flagella Reveal Novel Insights into Their Assembly and Function"
|
11:30 am - 11:35 am |
Discussion
|
11:35 am - 11:55 am |
Joanne Engel (University of California, San Francisco, USA)
"A Chp off the Old Block: Pseudomonas aeruginosa Uses Mechanochemical Signaling to Activate a Surface-Dependent Virulence Program"
|
11:55 am - 12:00 pm |
Discussion
|
12:00 pm - 12:10 pm |
Shanice Webster (Geisel School of Medicine, Dartmouth College, USA)
"Novel Role for the Type IV Pili Alignment Complex in Cyclic-di-GMP Signaling and Biofilm Formation by Pseudomonas aeruginosa"
|
12:10 pm - 12:15 pm |
Discussion
|
12:15 pm - 12:25 pm |
Lisa Kahl (Columbia University, USA)
"Light and Temperature Cycling Elicits Metabolic Patterns in Pseudomonas aeruginosa Biofilms"
|
12:25 pm - 12:30 pm |
Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 9:30 pm |
Microbial Communities and Communication
Discussion Leader: Marie Elliot (McMaster University, Canada)
|
7:30 pm - 7:35 pm |
Introduction by Discussion Leader
|
7:35 pm - 7:55 pm |
Lars Dietrich (Columbia University, USA)
"The Interplay of Metabolism and Structure in Bacterial Biofilms"
|
7:55 pm - 8:00 pm |
Discussion
|
8:00 pm - 8:20 pm |
Knut Drescher (Max Planck Institute for Terrestrial Microbiology, Germany)
"Unicellular and Multicellular Processes in Biofilm Responses to Stress"
|
8:20 pm - 8:25 pm |
Discussion
|
8:25 pm - 8:35 pm |
Julie Valastyan (Princeton University, USA)
"S. cerevisiae Produce MHF, a Mimic of Bacterial Autoinducer-2"
|
8:35 pm - 8:40 pm |
Discussion
|
8:40 pm - 9:00 pm |
Karine Gibbs (Harvard University, USA)
"Identity, Development and Collective Motility in Proteus mirabilis"
|
9:00 pm - 9:05 pm |
Discussion
|
9:05 pm - 9:25 pm |
Mark Mandel (University of Wisconsin-Madison, USA)
"Biofilm Regulatory Evolution in Squid-Colonizing Vibrio fischeri"
|
9:25 pm - 9:30 pm |
Discussion
|
Friday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am |
Departure
|