Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
ECM and Stem Cell Fate Regulation
Discussion Leader: Kris Kilian (University of New South Wales, Australia)
7:40 pm - 8:20 pm
Samira Musah (Duke University, United States)
"Human Disease Models for Uncovering Novel Therapeutic Targets"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 9:10 pm
Randolph Ashton (University of Wisconsin, United States)
"Bioengineering CNS Morphogenesis for Scalable Application in Regulatory Science and Regenerative Medicine"
9:10 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Organoids
Discussion Leader: Alex Hughes (University of Pennsylvania, United States)
9:00 am - 9:40 am
Jianping Fu (University of Michigan, Ann Arbor, United States)
"Bottom-up Synthetic Embryology for Understanding Early Human Development"
9:40 am - 9:50 am
Discussion
9:50 am - 10:00 am
Short Talk Selected from Poster Abstracts
10:00 am - 10:05 am
Discussion
10:05 am - 10:35 am
Coffee Break
10:35 am - 11:15 am
Nuria Montserrat (Institute for Bioengineering of Catalonia (IBEC), Spain)
"Engineering Organoids from Human Pluripotent Stem Cells to Understand Human Development and Disease"
11:15 am - 11:25 am
Discussion
11:25 am - 12:05 pm
Kelly Stevens (University of Washington, United States)
"Multi-dimensional Assembly of Human Organoids to Organs to Societies"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizer: Sarah Heilshorn (Stanford University, United States)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Organs-on-a-Chip
Discussion Leader: Peter Loskill (University of Tübingen, Germany)
7:30 pm - 8:10 pm
Nancy Allbritton (University of Washington, Seattle, United States)
"Development of Novel Intestine-on-Chip Models"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:30 pm
Short Talk Selected from Poster Abstracts
8:30 pm - 8:35 pm
Discussion
8:35 pm - 9:15 pm
Roger Kamm (Massachusetts Institute of Technology, United States)
"Matrix Remodeling During Vasculogenesis in Microphysiological Systems"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Advanced Engineered ECMs
Discussion Leader: Shyni Varghese (Duke University, United States)
9:00 am - 9:40 am
Sarah Heilshorn (Stanford University, United States)
"Bespoke Biopolymeric Matrices: Towards Personalized Tissue Mimics"
9:40 am - 9:50 am
Discussion
9:50 am - 10:00 am
Short Talk Selected from Poster Abstracts
10:00 am - 10:05 am
Discussion
10:05 am - 10:35 am
Coffee Break
10:35 am - 11:15 am
Cole DeForest (University of Washington, United States)
"Digital Dynamic Customization of the Cellular Niche"
11:15 am - 11:25 am
Discussion
11:25 am - 12:05 pm
Jason Burdick (University of Colorado Boulder, United States)
"Biofabrication Approaches to Engineer 3D ECM Structure and Organization"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Single Cell Biology and Development
Discussion Leader: Karthik Shekhar (Broad Institute of MIT and Harvard, United States)
7:30 pm - 8:10 pm
Siddharth Dey (University of California, Santa Barbara, United States)
"Integrated Single-cell Sequencing Reveals Principles of Epigenetic Regulation of Early Mouse and Human Development"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:30 pm
Short Talk Selected from Poster Abstracts
8:30 pm - 8:35 pm
Discussion
8:35 pm - 9:15 pm
Tom Nowakowski (University of California, San Francisco, United States)
"Establishing Tools to Study the Emergence of Cellular Diversity in the Human Brain"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
ECM Mechanobiology
Discussion Leader: Catherine Kuo (University of Maryland, United States)
9:00 am - 9:40 am
Xavier Trepat (Institute for Bioengineering of Catalonia (IBEC), Spain)
"Engineering Epithelial Shape and Mechanics from the Bottom Up"
9:40 am - 9:50 am
Discussion
9:50 am - 10:00 am
Short Talk Selected from Poster Abstracts
10:00 am - 10:05 am
Discussion
10:05 am - 10:35 am
Coffee Break
10:35 am - 11:15 am
Ovijit Chaudhuri (Stanford University, United States)
"Cell Migration and Morphogenesis in Viscoelastic Extracellular Matrices"
11:15 am - 11:25 am
Discussion
11:25 am - 12:05 pm
Celeste Nelson (Princeton University, United States)
"The Coupling Between Matrix Dynamics, Cell Fate, and Tissue Form"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Engineering and Application of Immunomodulatory Materials
Discussion Leader: Katharina Maisel (University of Maryland, United States)
7:30 pm - 8:10 pm
Kei Kishimoto (Selecta Biosciences, United States)
"Preclinical and Clinical Development of Tolerogenic Nanoparticles to Induce Antigen-specific Immune Tolerance"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:30 pm
Short Talk Selected from Poster Abstracts
8:30 pm - 8:35 pm
Discussion
8:35 pm - 9:15 pm
Ankur Singh (Georgia Institute of Technology, United States)
"Materials and Interfaces for Engineering B and T Cell Lymphocytes"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Bioinspired Fabrication
Discussion Leader: Fabien Guillemot (Poietis, France)
9:00 am - 9:40 am
Jordan Miller (3D Systems, United States)
"Expanding the Design Space of Engineered Tissues"
9:40 am - 9:50 am
Discussion
9:50 am - 10:00 am
Short Talk Selected from Poster Abstracts
10:00 am - 10:05 am
Discussion
10:05 am - 10:35 am
Coffee Break
10:35 am - 11:15 am
Tatiana Segura (Duke University, United States)
"Design and Function of Granular Materials"
11:15 am - 11:25 am
Discussion
11:25 am - 12:05 pm
Akhilesh Gaharwar (Texas A&M University, United States)
"Mineralomics: Designing Mineral-based Biomaterials for in situ Tissue Regeneration"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Keynote Session: Exploring and Manipulating the Cell-Matrix Interface in Health and Disease
Discussion Leader: Adam Engler (University of California, San Diego, United States)
7:30 pm - 8:20 pm
Valerie Weaver (University of California, San Francisco, United States)
"Keynote Address: Tension-dependent Metabolic Reprogramming and Anti-tumor Immunity"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 9:20 pm
Juergen Knoblich (Institute of Molecular Biotechnology (IMBA), Austria)
"Keynote Address: Cerebral Organoids: Modeling Human Brain Development and Neurological Disorders in 3D Cell Culture"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure