| SATURDAY |
| 1:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Engineered-ECM Cues for Stem Cell Differentiation and Survival |
| Discussion Leaders: Jason Burdick (University of Pennsylvania) and Brandon Blakely (National Institute of Standards and Technology) |
| 3:45 pm - 4:00 pm | Simone Allazetta (École Polytechnique Fédérale de Lausanne)
"Biomechanical and Biochemical Modulation of Cellular Microniches Using Droplet-Based Microfluidics" |
| 4:00 pm - 4:07 pm | Discussion |
| 4:07 pm - 4:22 pm | Chun Yang (University of Colorado Boulder)
"YAP Mediates Extracellular Mechanotransduction in Human Mesenchymal Stem Cells in 3D Thiol-ene Hydrogels" |
| 4:22 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I (Last Names Beginning A-M) |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | From Tissue Form to Cell Function |
| Discussion Leaders: Linda Griffith (Massachusetts Institute of Technology) and Julianne Holloway (University of Pennsylvania) |
| 7:30 pm - 7:50 pm | Lauren Barney (University of Massachusetts Amherst)
"Integrin Binding Uniquely Regulates Tropic Breast Cancer Cell Phenotypes In Vitro" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Jelena Rnjak (University of New South Wales)
"Engineering Biomimetic Materials by Utilizing the Multifaceted Role of Perlecan Domain V in the Vascular Niche" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Steven Caliari (University of Pennsylvania)
"Mechanically Dynamic Hydrogels for Probing Hepatic Stellate Cell Response in Fibrosis and Regression" |
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Brendon Baker (Boston University)
"Mesenchymal Stem Cell Mechanosensing in Engineered Fibrillar Microenvironments" |
| 9:20 pm - 9:30 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Molecular Mechanisms of Cell-ECM Signaling |
| Discussion Leaders: Jorge Valdez (Massachusetts Institute of Technology) and Colin Choi (Boston University) |
| 9:00 am - 9:20 am | Guanqing Ou (University of California Berkeley)
"Extracellular Matrix Stiffness Potentiates EGFR Activation and Endocytosis in Mammary Epithelial Cells" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Ruchi Malik (Fox Chase Cancer Center)
"Desmoplastic Stroma Affects Growth and Invasion of Progressively Mutated Human Pancreatic Cancer Cell In Vitro" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | De-Yao Wang (University of Manchester)
"The Role of Integrin Mediated Adhesions in Neuronal Mechanosensing" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 10:50 am | Karin Wang (Cornell University)
"Early Tumor-Associated Fibronectin Matrices Promote the Development of a Tumor Microenvironment" |
| 10:50 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II (Last Names Beginning N-Z) |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Mentor Roundtable Discussion |
| Discussion Leaders: Jason Burdick (University of Pennsylvania) and Linda Griffith (Massachusetts Institute of Technology) |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
