Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: The Dynamic Life of Synapses
Discussion Leader: Chiara Cirelli (University of Wisconsin - Madison School of Medicine and Public Health, United States)
7:40 pm - 7:55 pm
Introduction by Discussion Leader
7:55 pm - 8:45 pm
Seth Grant (University of Edinburgh, United Kingdom)
"The Role of Sleep and Experience in Shaping the Synaptome Architecture"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
Marie-Eve Tremblay (University of Victoria, Canada)
"Microglial Response to Sleep Deprivation Depends on the Hippocampal Region and the Paradigm Used in Adult Male Mice"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
REM Sleep Dynamics, Models and Dreams
Discussion Leader: Hiroki Ueda (The University of Tokyo/RIKEN Center for Biosystems Dynamics Research (BDR) , Japan)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:40 am
Giulio Bernardi (IMT School for Advanced Studies Lucca, Italy)
"Global and Local Brain Activity Patterns in Human REM Sleep and Their Relationship with Dream Experiences"
9:40 am - 9:50 am
Discussion
9:50 am - 10:20 am
Carolina Gutierrez Herrera (University of Bern, Switzerland)
"Unlocking the Enigma of REM Onset: Neuro-Astrocyte Circuits in Sleep Regulation"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:25 am
Yanhua Huang (University of Pittsburgh, United States)
"A Sleep EEG Signature of MCH Neuron Activities Predicts Cocaine Seeking in Rats"
11:25 am - 11:35 am
Discussion
11:35 am - 12:05 pm
Franz Weber (University of Pennsylvania, United States)
"Brainstem Dynamics Regulating REM Sleep"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Simone Bellini (Zentrum für Experimentelle Neurologie (ZEN), Inselspital, Universität Bern, Bern, Switzerland)
"Context-Specific Hypothalamic Regulation of REM Sleep"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizer: Valerie Mongrain (Université de Montréal, Canada)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Quantifying EEG Oscillations, Dynamics and Their Functional and Physiological Correlates
Discussion Leader: Ines Violante (University of Surrey, United Kingdom)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
Alpar Lazar (University of East Anglia, United Kingdom)
"The Circadian and Sleep-Wake History Dependent Regulation of Brain Oscillatory Activity and Connectivity: Associations with Cognition"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
Niels Niethard (Universtity of Tuebingen, Germany)
"Sleep Oscillations and Synaptic Plasticity: A Circuit Perspective"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
Róbert Bódizs (Semmelweis University, Hungary)
"On the Power Law Scaling of the Electroencephalogram and its Relevance in Understanding Sleep Regulation"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:25 pm
Angela D'Rozario (Macquarie University, Australia)
"Regional Patterns of Brain Activity and Memory Consolidation in Older Adults at Risk for Dementia"
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Molecular and Functional Correlates of Sleep and Sleep Loss in Rodents and Flies
Discussion Leader: Vladyslav Vyazovskiy (University of Oxford, United Kingdom)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:40 am
Aarti Jagannath (University of Oxford, United Kingdom)
"A Multiomics Approach to Understanding the Molecular Landscape of Sleep and Circadian Rhythm Regulation"
9:40 am - 9:50 am
Discussion
9:50 am - 10:20 am
Iris Titos (University of Utah, United States)
"A Gut-Secreted Neuropeptide Regulates Arousal"
10:20 am - 10:30 am
Discussion
10:30 am - 11:05 am
Coffee Break
11:05 am - 11:35 am
Chunghun Lim (KAIST, South Korea)
"Lessons from Comparative Analyses of Ancestral Sleep Mechanisms"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
Leandro Fosque (Washington University in St Louis, United States)
"Sleep Restores an Optimal Computational Regime in Cortical Networks"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Jeff Donlea (UCLA, United States)
"Sleep Deprivation Drives Brain-Wide Changes in Cholinergic Pre-Synapse Abundance in Drosophila Melanogaster"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Nicolette Ognjanovski (University of Michigan, United States)
"Stable Excitatory Neuron Activity Persists in a Dynamic Hippocampus Across the Circadian Day"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Activation, Reactivation and the Role of Sleep and Sleep Circuits in Motor Learning
Discussion Leader: Alejandro Osorio-Forero (Netherlands Institute of Neuroscience, The Netherlands)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
James Dooley (Purdue University, United States)
"In Weanling Rats: Neural Interactions Between M1 and the Red Nucleus (A Brainstem Motor Nucleus) are Exclusive to Periods of REM Sleep"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:35 pm
Genevieve Albouy (University of Utah, United States)
"Role of the Hippocampus in Wake- and Sleep-Related Motor Memory Consolidation"
8:35 pm - 8:40 pm
Discussion
8:40 pm - 9:05 pm
Karunesh Ganguly (UCSF, United States)
"Dynamics of Cross-Area Coupling During Motor Memory Consolidation"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Andrew Varga (Icahn School of Medicine at Mount Sinai, United States)
"Unique Roles for REM Sleep and Slow Wave Sleep in the Sleep-Dependent Evolution of Brain Circuits Supporting Spatial Navigational Memory"
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Extracting Sleep and Circadian Parameters From Big and Longitudinal Data
Discussion Leader: Jelena Tadic (University of Graz, Austria)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:45 am
Shaun Purcell (Brigham & Women's Hospital, Harvard Medical School, United States)
"Quantifying Sleep Architecture in Large-Scale Datasets: Tools, Opportunities and Challenges"
9:45 am - 9:55 am
Discussion
9:55 am - 10:25 am
Janet Mullington (Beth Israel Deaconess Medical Center, United States) and Haoqi Sun (Beth Israel Deaconess Medical Center, United States)
"Sleep and Long-Term Covid"
10:25 am - 10:35 am
Discussion
10:35 am - 11:10 am
Coffee Break
11:10 am - 11:40 am
Andrew Phillips (Monash University, Australia)
"How Sleep Regularity and Light Exposure Patterns Influence Health in >85,000 Participants"
11:40 am - 11:50 am
Discussion
11:50 am - 12:20 pm
Anne Skeldon (University of Surrey, United Kingdom)
"Determining Whether Sleep Phenotypes are Driven by Endogenous Circadian Rhythms of Environmental Light by Combining Longitudinal Data and Personalized Mathematical Models"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Modulating Remembering and Forgetting by Sleep and Neuromodulation
Discussion Leader: Reto Huber (University Children's Hospital Zurich, Switzerland)
7:30 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:10 pm
Steffen Gais (University of Tübingen, Germany)
"Getting Declarative Memory into the Neocortex: What Is the Function of Sleep?"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
Lisa Genzel (Donders Institute for Brain, Cognition and Behavior, Radboud University, The Netherlands)
"Semantic-Like Memories in Rodents"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
Yuval Nir (Tel Aviv University, Israel)
"Intracranial Closed-Loop Stimulation in Human Sleep Boosts Hippocampal–Prefrontal Synchrony and Memory"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Dynamics and Contribution of Glia to Sleep Regulation
Discussion Leader: Peter Meerlo (University of Groningen, The Netherlands)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:40 am
Don van Meyel (McGill University, Canada)
"Regulation of Drosophila Sleep Through Transport and Metabolism of Neuromodulators by Distinct Glial Cell Types"
9:40 am - 9:50 am
Discussion
9:50 am - 10:20 am
Michael Lazarus (WPI-International Institute for Integrative Sleep Medicine, Japan)
"The Teleological Mystery of Sleep - Glioneuronal Mechanisms Integrating Sleep Homeostasis and Motivation"
10:20 am - 10:30 am
Discussion
10:30 am - 11:05 am
Coffee Break
11:05 am - 11:35 am
Kazue Semba (Dalhousie University, Canada)
"Sleep History-Dependent Astrocytic Structural Remodeling at Synapses to Orexin Neurons in the Lateral Hypothalamus"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
Sha Liu (VIB-KU Leuven, Belgium)
"Single-Cell Transcriptomics Reveals that Glial Cells Integrate Homeostatic and Circadian Processes to Drive Sleep-Wake Cycles"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Annika Barber (Rutgers, the State University of New Jersey, United States)
"Glial Contributions to Sleep and Circadian Disorders After Traumatic Brain Injury in Drosophila"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Aurélie Brécier (CRNL, Université Claude Bernard Lyon 1, France)
"Activity of Layer-1 Neurogliaform Neurons Across Sleep Stages and in Relation with Sleep Oscillations"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Locus Coeruleus, Sleep and Attention
Discussion Leader: Dara Manoach (Massachusetts General Hospital and Harvard Medical School, United States)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
Anita Luthi (University of Lausanne, Switzerland)
"Locus coeruleus Activity Fluctuations in Mouse Non-REM Sleep: Coordinators of Brain and Peripheral Rhythms, Gatekeepers of the Non-REM-REM Sleep Cycle"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:35 pm
Celia Kjaerby (University of Copenhagen, Denmark)
"The Role of Locus Coeruleus Activity During Sleep in Age-Related Cognitive Decline"
8:35 pm - 8:40 pm
Discussion
8:40 pm - 9:00 pm
Gilles Vandewalle (GIGA-Cyclotron Research Centre-In Vivo Imaging, Belgium)
"In vivo Imaging of Locus Coeruleus and Hypothalamus Contributions to Sleep Regulation in Humans"
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:25 pm
Bruno van Swinderen (Queensland Brain Institute, Australia)
"A Role for Sleep in Regulating Predictions in Drosophila"
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure