Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Enzymes and Biocatalysis
Discussion Leader: Alexandra Paton (University of Michigan, United States)
3:45 pm - 4:15 pm
Alison Narayan (University of Michigan, United States)
"Making Connections between Protein Sequences and Chemical Space to Enable Biocatalytic Synthesis"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Light and Chirality
Discussion Leader: Gino Occhialini (Massachusetts Institute of Technology, United States)
7:30 pm - 7:50 pm
Niklas Pflaum (Technical University of Munich (TUM), Germany)
"At the Edge of Photochemical Deracemization: Cleavage Pathways of Chiral Spirocyclic Oxetane Indolones"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Diego Granados (Princeton University, United States)
"Abstraction of Strong C–H Bonds Enabled by a Brønsted Basic Ir Photocatalyst"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Sojung Kim (University of California, Berkeley, United States)
"Mechanistic Elucidation and Interrogation of Enantioselectivity of Photomediated Ring Contractions of Saturated Heterocycles"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Nelson Lam (University of Cambridge, United Kingdom)
"Light-Driven Catalytic Enantioselective Oxidation of Meso Diols"
9:20 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Transition Metals and Enzymes in Stereochemistry
Discussion Leader: Mingkai Zhang (boston college, United States)
9:00 am - 9:25 am
Dennis Kutateladze (MIT, United States)
"Automated Flow Synthesis of Artificial Heme Enzymes for Enantioselective Biocatalysis"
9:25 am - 9:40 am
Discussion
9:40 am - 10:05 am
Mingxin Liu (Purdue University, United States)
"Catalytic Stereocontrolled Carbene and Vinylidene Transfer Reactions"
10:05 am - 10:20 am
Discussion
10:20 am - 10:45 am
Kyan D'Angelo (University of California, Berkeley, United States)
"Borylation of Alkyl C–H Bonds Enables the Generation of Molecular Complexity in Three Dimensions"
10:45 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Synthetic Methods
Discussion Leader: Sara Alektiar (University of Wisconsin-Madison, United States)
1:30 pm - 1:50 pm
Sean Treacy (University of California, Berkeley, United States)
"Data Science Abstracts Reactivity of Ternary Supramolecular Adducts"
1:50 pm - 2:00 pm
Discussion
2:00 pm - 2:20 pm
Marissa Lavagnino (Massachusetts Institute of Technology, United States)
"Stereoinvertive Deoxyfluorination of Alcohols by Nonbasic Activation and Fluoride Shuttling"
2:20 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes