Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Pathogen-Derived Modulators and the Interaction with Host Immunity
Discussion Leader: Jesus Valenzuela (National Institute of Allergy and Infectious Diseases, NIH, United States)
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:30 pm
Henry McSorley (University of Dundee, UK, United Kingdom)
"Helminth-Derived Modulators of the IL-33 Pathway"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:00 pm
Patricia Aguilar (UTMB, United States)
"Immune Evasion Strategies of Emerging Tick-Borne Banyangvirus"
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:25 pm
David Corry (Baylor College of Medicine, United States)
"Immunologic Basis of Chronic Disease: Lessons from Fungi"
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Microbiota, Infection and Immune Regulation
Discussion Leader: Pedro Gazzinelli-Guimaraes (NIAID-NIH, United States)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:35 am
Stacey Burgess (UVA, United States)
"Gut Microbiome Communication with Bone Marrow and Regulation of Severity of Mucosal Infection"
9:35 am - 9:40 am
Discussion
9:40 am - 10:00 am
James Collins (University of Texas Southwestern Medical Center, United States)
"The Mechanism of Male-induced Female Sexual Development in Schistosomes"
10:00 am - 10:05 am
Discussion
10:05 am - 10:25 am
Ricardo Fujiwara (Universidade Federal de Minas Gerais, Brazil)
"Immunomodulation and Beyond: Impact of Ascariasis During Parasite Establishment and Host's Health"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Momar Ndao (McGill University, Canada)
"Prophylactic Activity of an Adenovirus Vectored Bicistronic Schistosoma mansoni Vaccine expressing Cathepsin B and Tetraspanin 2 in Mice"
11:20 am - 11:25 am
Discussion
11:25 am - 11:45 am
Elizabeth McGraw (Penn State University, United States)
"Thermal Adaptation in the Dengue Virus: Aedes Aegypti System"
11:45 am - 11:50 am
Discussion
11:50 am - 12:00 pm
Late-Breaking Topic
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:15 pm
Short Talk Selected from Poster Abstracts
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Sara Lustigman (New York Blood Center, United States) and Luis Martinez (University of Florida, United States)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Disrupting Transmission and Advances in Disease Control and Elimination
Discussion Leader: Fabiano Oliveira (National Institutes of Health, United States)
7:30 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:05 pm
Cheolho Sim (Baylor University, United States)
"Molecular Mechanism of Mosquito Diapause: Implications in Vector-borne Disease Dynamics"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
Rhoel Dinglasan (University of Florida Emerging Pathogens Institute, United States)
"Molecular Dissection of Vector-borne Pathogen Transmission Through a "Systems Lens": A Path Towards the Development of Novel Interventions for Disease Elimination"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
Jayhun Lee (The University of Texas Health Science Center at Houston, United States)
"The Very Hungry Parasite: Discovering the Mechanism of Schistosome Immune Evasion"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Sarah Fortune (Harvard T.H. Chan School of Public Health, United States)
"Building the Path to Tailored TB Treatment: Mycobacterial Determinants of Treatment Responses"
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
High-Throughput Approaches for the Understanding of Tropical Infections
Discussion Leader: Pei-Yong Shi (University of Texas Medical Branch, United States)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:35 am
Makedonka Mitreva (WUSTL, United States)
"Genomic Surveillance of Triclabendazole Resistant Fasciola Hepatica"
9:35 am - 9:40 am
Discussion
9:40 am - 10:00 am
Gustavo Fontecha (Universidad Nacional Autónoma de Honduras, Honduras)
"Strengthening of Epidemiological Surveillance for the Elimination of Malaria: The Contribution of the Academy"
10:00 am - 10:05 am
Discussion
10:05 am - 10:25 am
Sebastian Lourido (Whitehead Institute, Massachusetts Institute of Technology, United States)
"A Functional Genomics Guide to the Adaptations of Apicomplexan Parasites"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Laura-Isobel McCall (University of Oklahoma, United States)
"Metabolomics-Enabled Insights Into Antiparasitic Treatment Success and Failure"
11:20 am - 11:25 am
Discussion
11:25 am - 11:45 am
Philip Felgner (University of California Irvine, United States)
"Multiplex Lipid Nanoparticle Adjuvants: Vaccine Efficacy and Mechanisms"
11:45 am - 11:50 am
Discussion
11:50 am - 12:00 pm
Late-Breaking Topic
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:15 pm
Short Talk Selected from Poster Abstracts
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Systems Biology, Big Data and the Role of Artificial Intelligence
Discussion Leader: Joel Vega-Rodriguez (NIH, United States)
7:30 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:05 pm
Galit Alter (Ragon Institute, United States)
"Systems Serology to Define Correlates of Immunity Against Malaria"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
Kamal Rawal (Amity University, India)
"Building an Artificial Intelligence-based System for Tropical Infectious Disease Vaccine Development"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
Hayden Metsky (Broad Institute of MIT and Harvard, United States)
"Designing Sensitive Viral Diagnostics with Machine Learning"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Anne De Groot (EpiVax, Inc.)
"Computational Vaccinology to Advance Vaccines Against Emerging and Tropical Diseases"
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Technology Innovations for the Detection, Prevention and Treatment of Tropical Infections
Discussion Leader: Serap Aksoy (Yale University School of Medicine, United States)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:35 am
Mattie Pawlowic (University of Dundee, United Kingdom)
"Creating a Comprehensive Mode-Of-Action Toolkit to Enable Cryptosporidium Drug Discovery"
9:35 am - 9:40 am
Discussion
9:40 am - 10:00 am
Paul Brindley (George Washington University, United States)
"Knockout of Liver Fluke Granulin Impedes Malignant Transformation During Infection with Opisthorchis Viverrini "
10:00 am - 10:05 am
Discussion
10:05 am - 10:25 am
Kelli Barr (University of South Florida, United States)
"Stem Cell-Based Models for Chikungunya Pathogenesis"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Cristina Poveda (Baylor College of Medicine, United States)
"mRNA-based Vaccine Development against Tropical Infectious Diseases"
11:20 am - 11:25 am
Discussion
11:25 am - 11:45 am
Timothy Anderson (Texas Biomedical Research Institute, United States)
"Powerful New Approaches utilizing Parasite Genetic Crosses"
11:45 am - 11:50 am
Discussion
11:50 am - 12:00 pm
Late-Breaking Topic
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:15 pm
Short Talk Selected from Poster Abstracts
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Ecology and Field-Based Epidemiology
Discussion Leader: Ana Sanchez (Brock University, Canada)
7:30 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:05 pm
Eric Dumonteil (Tulane University, United States)
"From the Ecology of Trypanosoma cruz i Transmission to the Molecular Pathogenesis of Chagas Disease"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
Andrea Graham (Princeton University, United States)
"Where the Wild Things Are: How Environment Hones Mammal-Worm-Germ Symbioses and Immune Phenotypes"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
Tamar Carter (Baylor University, United States)
"Genomic Approaches for Tracking the Spread and Evolution of Invasive Anopheles stephensi "
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Sarah Gunter (Baylor College of Medicine)
"Investigation of Chagas Disease Transmission in Northern Belize"
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Tropical Disease Interactions, Synergy and Interference
Discussion Leader: Julie Gutman (Centers for Disease Control and Prevention)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:35 am
Antonio Marcilla (Universitat de València, Spain)
"Extracellular Vesicles From Helminths: New Control Tools for Neglected Diseases"
9:35 am - 9:40 am
Discussion
9:40 am - 10:00 am
Alfredo Torres (University of Texas Medical Branch, United States)
"Burkholderia pseudomallei as an Enteric Pathogen: Defining the Bacterial and Host Factors Associated with Gastrointestinal Infection."
10:00 am - 10:05 am
Discussion
10:05 am - 10:25 am
Vanessa Ezenwa (Yale University, United States)
"Helminth-Tuberculosis Interactions: An Ecological Perspective"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Carmenza Spadafora (Instituto de Investigaciones Científicas y Servicios de Alta Tecnología (INDICASAT AIP), Panama)
"A Novel Alternative for the Treatment of Malaria: Electromagnetism?"
11:20 am - 11:25 am
Discussion
11:25 am - 11:45 am
Melissa Lodoen (University of California, Irvine, United States)
"Innate immune Responses to Toxoplasma gondii Infection"
11:45 am - 11:50 am
Discussion
11:50 am - 12:00 pm
Late-Breaking Topic
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:15 pm
Short Talk Selected from Poster Abstracts
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Keynote Session: Pathogen Modulators and Host Immunity
Discussion Leader: Fabian Gusovsky (Eisai Inc, United States)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:10 pm
Igor Almeida (University of Texas at El Paso, United States)
"High Prevalence of Trypanosoma Cruzi Infections in Hospitalized Parturient Women in the US-Mexico Border"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:45 pm
R. Kip Guy (University of Kentucky, United States)
"The Development of SJ733 as a Rapidly Acting Drug for Treatment of Malaria"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
Bruce Y. Lee (City University of New York)
"Systems Modeling, AI, Big Data, and Technology: Bringing it All Together for Tropical Infectious Disease Decision-Making and Communication"
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
Closing Remarks
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure