Sunday 
 
 
2:00 pm - 9:00 pm 
	
Arrival and Check-in
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 7:40 pm 
	
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
 
 
						
7:40 pm - 9:30 pm 
	
Establishing Vascular Heterogenity 
 
 
 
						
7:40 pm - 8:00 pm 
	
General Discussion
 
 
						
8:00 pm - 8:20 pm 
	
"Contributions of Persistent Injury-Associated Endothelial Cell States to Tissue Regeneration" 
 
 
 
						
8:20 pm - 8:30 pm 
	
Discussion
 
 
						
8:30 pm - 8:50 pm 
	
"Coronary Cell Heterogeneity in Disease" 
 
 
 
						
8:50 pm - 9:00 pm 
	
Discussion
 
 
						
9:00 pm - 9:20 pm 
	
"Stromal Plasticity from Development to Decline" 
 
 
 
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						
	Monday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am - 12:30 pm 
	
Maintaining Vascular Heterogeneity: Resilience 
 
 
 
						
9:00 am - 9:20 am 
	
"Vascular Resilience and Cardiovascular Health: Adapting, Recovering, and Thriving Under Stress" 
 
 
 
						
9:20 am - 9:30 am 
	
Discussion
 
 
						
9:30 am - 9:50 am 
	
"Insight Into the Development of Intraosseous Vascular Malformations" 
 
 
 
						
9:50 am - 10:00 am 
	
Discussion
 
 
						
10:00 am - 10:10 am 
	
"CXCL12 Drives Natural Variation in Coronary Artery Anatomy Across Diverse Populations" 
 
 
 
						
10:10 am - 10:15 am 
	
Discussion
 
 
						
10:15 am - 10:25 am 
	
"Dynamic Resilience of Cardiac Endothelial Cells During Myocardial Remodeling" 
 
 
 
						
10:25 am - 10:30 am 
	
Discussion
 
 
						
10:30 am - 11:00 am 
	
Group Photo / Coffee Break
 
 
						
11:00 am - 11:20 am 
	
"Maintenance of Lymphatic Function by Cell-Cell Junctions" 
 
 
 
						
11:20 am - 11:30 am 
	
Discussion
 
 
						
11:30 am - 11:40 am 
	
"Phenotyping 'Fibrosis-Associated' EC Subtypes In Progressive Liver Disease" 
 
 
 
						
11:40 am - 11:45 am 
	
Discussion
 
 
						
11:45 am - 12:05 pm 
	
"Vascular Diversity in the Brain" 
 
 
 
						
12:05 pm - 12:15 pm 
	
Discussion
 
 
						
12:15 pm - 12:30 pm 
	
Poster Previews
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 9:30 pm 
	
Regulation by Mechanical Forces 
 
 
 
						
7:30 pm - 7:50 pm 
	
"Exploring the Mechanics of the Zebrafish Anteroposterior Axis" 
 
 
 
						
7:50 pm - 8:00 pm 
	
Discussion
 
 
						
8:00 pm - 8:20 pm 
	
"How Fluid Shear Stress Determines Endothelial Cell Phenotype" 
 
 
 
						
8:20 pm - 8:30 pm 
	
Discussion
 
 
						
8:30 pm - 8:40 pm 
	
"Flow Mediated Membrane Lipid Composition and Endothelial Cell Homeostasis" 
 
 
 
						
8:40 pm - 8:45 pm 
	
Discussion
 
 
						
8:45 pm - 8:55 pm 
	
"Novel Players in Lymphatic Valve Formation" 
 
 
 
						
8:55 pm - 9:00 pm 
	
Discussion
 
 
						
9:00 pm - 9:20 pm 
	
"Vascular Differentiation and Morphogenesis" 
 
 
 
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						
	Tuesday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am - 12:30 pm 
	
Epigenetic Regulation and Epitranscriptomics 
 
 
 
						
9:00 am - 9:20 am 
	
"Leveraging Chromatin-Remodeling Enzymes To Study Vascular Development and Maintenance" 
 
 
 
						
9:20 am - 9:30 am 
	
Discussion
 
 
						
9:30 am - 9:50 am 
	
"Decoding mRNA Translation Control During Angiogenesis" 
 
 
 
						
9:50 am - 10:00 am 
	
Discussion
 
 
						
10:00 am - 10:10 am 
	
"An Epigenetic Link Between Metabolism and Smooth Muscle Cell Differentiation in Acta2  p.R179 Cells" 
 
 
 
						
10:10 am - 10:15 am 
	
Discussion
 
 
						
10:15 am - 10:25 am 
	
"MicroRNA Regulation in Brain Vascular Development and Disease" 
 
 
 
						
10:25 am - 10:30 am 
	
Discussion
 
 
						
10:30 am - 11:00 am 
	
Coffee Break
 
 
						
11:00 am - 11:20 am 
	
"Epigenetic Regulation of Vascular Smooth Muscle Cell Function in Disease" 
 
 
 
						
11:20 am - 11:30 am 
	
Discussion
 
 
						
11:30 am - 11:40 am 
	
"Post-Transcriptional Regulation of Vascular Homeostasis by the RNA-Binding Protein PABPC1" 
 
 
 
						
11:40 am - 11:45 am 
	
Discussion
 
 
						
11:45 am - 12:05 pm 
	
"Breaking the Pause: Signal-Dependent Transcription Control in Vascular Growth and Function" 
 
 
 
						
12:05 pm - 12:15 pm 
	
Discussion
 
 
						
12:15 pm - 12:30 pm 
	
Poster Previews
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 9:30 pm 
	
Sex-Related Differences in Vascular Biology 
 
 
 
						
7:30 pm - 7:50 pm 
	
"Reproductive Hormone Effects on Endothelial Function in Humans" 
 
 
 
						
7:50 pm - 8:00 pm 
	
Discussion
 
 
						
8:00 pm - 8:20 pm 
	
"Systems Genetics of Sex Differences in Vascular Cell Gene Regulation" 
 
 
 
						
8:20 pm - 8:30 pm 
	
Discussion
 
 
						
8:30 pm - 8:40 pm 
	
"Transcriptomic Profiling of the Sex-linked Biological Pathways of Severe Pulmonary Arterial Hypertension Associated with Endothelial Cell Caveolin-1 Depletion and Chronic Hypoxia" 
 
 
 
						
8:40 pm - 8:45 pm 
	
Discussion
 
 
						
8:45 pm - 8:55 pm 
	
"Kdm5c, an X-Linked Epigenetic Modifier, Protects Females Against Aortic Pathology" 
 
 
 
						
8:55 pm - 9:00 pm 
	
Discussion
 
 
						
9:00 pm - 9:20 pm 
	
"Sex Differences in Atherosclerosis" 
 
 
 
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						
	Wednesday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am - 12:30 pm 
	
Imaging and Genomic Approaches 
 
 
 
						
9:00 am - 9:20 am 
	
"Sequencing-Free Whole Genome Spatial Transcriptomics at Molecular Resolution in Intact Tissue" 
 
 
 
						
9:20 am - 9:30 am 
	
Discussion
 
 
						
9:30 am - 9:50 am 
	
"Whole Animal 3D Vascular Imaging" 
 
 
 
						
9:50 am - 10:00 am 
	
Discussion
 
 
						
10:00 am - 10:10 am 
	
"Integrated Multiomic Analysis Identifies a Role for NF-KB Pathway in Coronary Microvascular Disease (CMVD)" 
 
 
 
						
10:10 am - 10:15 am 
	
Discussion
 
 
						
10:15 am - 10:25 am 
	
"The Villus Stroma in Lymphatic-Muscle Development and Stem Cell Homeostasis" 
 
 
 
						
10:25 am - 10:30 am 
	
Discussion
 
 
						
10:30 am - 11:00 am 
	
Coffee Break
 
 
						
11:00 am - 11:20 am 
	
"Identification and Function of Endothelial Cell Microproteins: Challenges and Opportunities" 
 
 
 
						
11:20 am - 11:30 am 
	
Discussion
 
 
						
11:30 am - 11:40 am 
	
"Computational Analysis of EC Transcriptomics Reveals Cell Cycle as a Key Regulator of Flow-Dependent Artery Remodeling" 
 
 
 
						
11:40 am - 11:45 am 
	
Discussion
 
 
						
11:45 am - 12:05 pm 
	
"Investigating Vascular Dynamics via 4D Imaging of Live Mouse Skin" 
 
 
 
						
12:05 pm - 12:15 pm 
	
Discussion
 
 
						
12:15 pm - 12:30 pm 
	
Poster Previews
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 9:30 pm 
	
Cellular Damage, Repair and Regeneration 
 
 
 
						
7:30 pm - 7:50 pm 
	
"Mechanisms Underlying Vascular Repair in Hindlimb Ischemia" 
 
 
 
						
7:50 pm - 8:00 pm 
	
Discussion
 
 
						
8:00 pm - 8:20 pm 
	
"Stomal Plasticity from Development to Decline" 
 
 
 
						
8:20 pm - 8:30 pm 
	
Discussion
 
 
						
8:30 pm - 8:40 pm 
	
"Understanding How Structural Components Shape Tissue and Cellular Dynamics by Imaging Live Mice" 
 
 
 
						
8:40 pm - 8:45 pm 
	
Discussion
 
 
						
8:45 pm - 8:55 pm 
	
"Cellular and Molecular Mechanisms of Lung Artery Growth" 
 
 
 
						
8:55 pm - 9:00 pm 
	
Discussion
 
 
						
9:00 pm - 9:20 pm 
	
"LINCing the Nucleus to Endothelial Cell Function in Blood Vessels" 
 
 
 
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						
	Thursday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
8:30 am - 9:00 am 
	
Business Meeting 
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s) 
 
 
						
9:00 am - 12:30 pm 
	
 
 
						
9:00 am - 9:20 am 
	
"Sphingolipid Metabolism and Signaling in the Vascular System" 
 
 
 
						
9:20 am - 9:30 am 
	
Discussion
 
 
						
9:30 am - 9:50 am 
	
"The Effect of Shear Stress on Endothelial Lipid Droplet Metabolism" 
 
 
 
						
9:50 am - 10:00 am 
	
Discussion
 
 
						
10:00 am - 10:10 am 
	
"Investigating the Role of Endothelial Dysfunction in Driving Diastolic Dysfunction in Mice with Inflammatory Arthritis" 
 
 
 
						
10:10 am - 10:15 am 
	
Discussion
 
 
						
10:15 am - 10:25 am 
	
"Impaired Insulin Signaling in Smooth Muscle Cells Reduces Smooth Muscle Cell Contribution to Atherosclerotic Lesion Development" 
 
 
 
						
10:25 am - 10:30 am 
	
Discussion
 
 
						
10:30 am - 11:00 am 
	
Coffee Break
 
 
						
11:00 am - 11:20 am 
	
"Metabolic Mechanisms Controlling Lymphatic Vascular Development" 
 
 
 
						
11:20 am - 11:30 am 
	
Discussion
 
 
						
11:30 am - 11:40 am 
	
"Loss of Endothelial PGC1α Causes Metabolic Dysfunction-Associated Fatty Liver Disease" 
 
 
 
						
11:40 am - 11:45 am 
	
Discussion
 
 
						
11:45 am - 11:55 am 
	
"Vascular Malformations in the Gastrointestinal Tract: A Novel VWF-Angiopoietin-Tie2 Organotypic Pathway" 
 
 
 
						
11:55 am - 12:00 pm 
	
Discussion
 
 
						
12:00 pm - 12:20 pm 
	
"Defining the Vascular Niche of Human Adipose Tissue Across Metabolic Conditions" 
 
 
 
						
12:20 pm - 12:30 pm 
	
Discussion
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 9:30 pm 
	
Congenital Vascular Disorders and Therapy 
 
 
 
						
7:30 pm - 7:50 pm 
	
"How Hereditary Hemorrhagic Telangiectasia  Prevents Hemorrhages?" 
 
 
 
						
7:50 pm - 8:00 pm 
	
Discussion
 
 
						
8:00 pm - 8:20 pm 
	
"GI Angiodysplasia: Vascular Malformations in Search of a Mechanism" 
 
 
 
						
8:20 pm - 8:30 pm 
	
Discussion
 
 
						
8:30 pm - 8:40 pm 
	
"Cerebral Cavernous Malformation 2 Loss-of-Function Suppresses Endothelial Inflammation and Reduces Murine Atherosclerosis" 
 
 
 
						
8:40 pm - 8:45 pm 
	
Discussion
 
 
						
8:45 pm - 8:55 pm 
	
"RNA Binding Protein Regulatory Networks in Cardiovascular Development and Disease" 
 
 
 
						
8:55 pm - 9:00 pm 
	
Discussion
 
 
						
9:00 pm - 9:20 pm 
	
"Unraveling Mechanisms and Therapeutic Targets for HHT through Endothelial Cells Derived from Mutant iPSCs" 
 
 
 
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						
	Friday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am 
	
Departure