Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Establishing Vascular Heterogenity
7:40 pm - 8:00 pm
General Discussion
8:00 pm - 8:20 pm
"Contributions of Persistent Injury-Associated Endothelial Cell States to Tissue Regeneration"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Coronary Cell Heterogeneity in Disease"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Vascular Plasticity in Liver Growth and Regeneration"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Maintaining Vascular Heterogeneity: Resilience
9:00 am - 9:20 am
"Vascular Resilience and Cardiovascular Health: Adapting, Recovering, and Thriving Under Stress"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Insight into the Development of Intraosseous Vascular Malformations"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"CXCL12 Drives Natural Variation in Coronary Artery Anatomy Across Diverse Populations"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Dynamic Resilience of Cardiac Endothelial Cells during Myocardial Remodeling"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Group Photo / Coffee Break
11:00 am - 11:20 am
"Maintenance of Lymphatic Function by Cell-Cell Junctions"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Vascular Diversity in the Brain"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Regulation by Mechanical Forces
7:30 pm - 7:50 pm
"Exploring the Mechanics of the Zebrafish Anteroposterior Axis"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"How Fluid Shear Stress Determines Endothelial Cell Phenotype"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Flow Mediated Membrane Lipid Composition and Endothelial Cell Homeostasis"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Novel Players in Lymphatic Valve Formation"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Vascular Differentiation and Morphogenesis"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Epigenetic Regulation and Epitranscriptomics
9:00 am - 9:20 am
"Leveraging Chromatin-Remodeling Enzymes To Study Vascular Development and Maintenance"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Decoding mRNA Translation Control During Angiogenesis"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"An Epigenetic Link Between Metabolism and Smooth Muscle Cell Differentiation in Acta2 p.R179 Cells"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"MicroRNA Regulation in Brain Vascular Development and Disease"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Epigenetic Regulation of Vascular Smooth Muscle Cell Function in Disease"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Breaking the Pause: Signal-Dependent Transcription Control in Vascular Growth and Function"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Sex-Related Differences in Vascular Biology
7:30 pm - 7:50 pm
"Reproductive Hormone Effects on Endothelial Function in Humans"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Systems Genetics of Sex Differences in Vascular Cell Gene Regulation"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Short Talk Selected from Poster Abstracts
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Kdm5c, an X-Linked Epigenetic Modifier, Protects Females Against Aortic Pathology"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Sex Differences in Atherosclerosis"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Imaging and Genomic Approaches
9:00 am - 9:20 am
"Artificial Intelligence and the Human Genome"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Whole Animal 3D Vascular Imaging"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Integrated Multiomic Analysis Identifies a Role for NF-KB Pathway in Coronary Microvascular Disease (CMVD)"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"The Villus Stroma in Lymphatic-muscle Development and Stem Cell Homeostasis"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Identification and Function of Endothelial Cell Microproteins: Challenges and Opportunities"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Computational Analysis of EC Transcriptomics Reveals Cell Cycle as a Key Regulator of Flow-Dependent Artery Remodeling"
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Investigating Vascular Dynamics via 4D Imaging of Live Mouse Skin"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Cellular Damage, Repair and Regeneration
7:30 pm - 7:50 pm
"Mechanisms Underlying Vascular Repair in Hindlimb Ischemia"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Stomal Plasticity from Development to Decline"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Understanding How Structural Components Shape Tissue and Cellular Dynamics by Imaging Live Mice"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Cellular and Molecular Mechanisms of Lung Artery Growth"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"LINCing the Nucleus to Endothelial Cell Function in Blood Vessels"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Sphingolipid Metabolism and Signaling in the Vascular System"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"The Effect of Shear Stress on Endothelial Lipid Droplet Metabolism"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Investigating the Role of Endothelial Dysfunction in Driving Diastolic Dysfunction in Mice with Inflammatory Arthritis"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Impaired Insulin Signaling in Smooth Muscle Cells Reduces Smooth Muscle Cell Contribution to Atherosclerotic Lesion Development"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Metabolic Mechanisms Controlling Lymphatic Vascular Development"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Loss of Endothelial PGC1α Causes Metabolic Dysfunction-Associated Fatty Liver Disease"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Vascular Malformations in the Gastrointestinal Tract: A Novel VWF-Angiopoietin-Tie2 Organotypic Pathway"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Defining the Vascular Niche of Human Adipose Tissue Across Metabolic Conditions"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Congenital Vascular Disorders and Therapy
7:30 pm - 7:50 pm
"How Hereditary Hemorrhagic Telangiectasia Prevents Hemorrhages?"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"GI Angiodysplasia: Vascular Malformations in Search of a Mechanism"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Short Talk Selected from Poster Abstracts
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"RNA Binding Protein Regulatory Networks in Cardiovascular Development and Disease"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Unraveling Mechanisms and Therapeutic Targets for HHT through Endothelial Cells Derived from Mutant iPSCs"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure