Sunday
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2:00 pm - 9:00 pm |
Arrival and Check-in
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6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 7:40 pm |
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
|
7:40 pm - 9:30 pm |
Keynote Session: Venom to Drugs
Discussion Leader: Yvonne Angell (ChemPartner, USA)
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7:40 pm - 7:45 pm |
Opening Remarks
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7:45 pm - 7:50 pm |
Introduction by Discussion Leader
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7:50 pm - 8:20 pm |
Baldomero Olivera (University of Utah, USA)
"Venom Discovery and Function from Pain to Diabetes"
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8:20 pm - 8:30 pm |
Discussion
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8:30 pm - 8:45 pm |
Bin Wu (Amgen Inc., USA)
"Discovery of Tarantula Venom-Derived NaV1.7-Inhibitory Peptide"
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8:45 pm - 8:50 pm |
Discussion
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8:50 pm - 9:20 pm |
Richard Lewis (The University of Queensland, Australia)
"Therapeutic Applications of Nature's Venom Arsenal"
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9:20 pm - 9:30 pm |
Discussion
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Monday
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7:30 am - 8:30 am |
Breakfast
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9:00 am - 12:30 pm |
Venom Evolution
Discussion Leader: Ronald Jenner (The Natural History Museum, United Kingdom)
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9:00 am - 9:05 am |
Introduction by Discussion Leader
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9:05 am - 9:35 am |
Nicholas Casewell (Liverpool School of Tropical Medicine, United Kingdom)
"Convergent Evolution and Neglected Vertebrate Venom Systems"
|
9:35 am - 9:45 am |
Discussion
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9:45 am - 10:15 am |
Greta Binford (Lewis & Clark College, USA)
"How the Brown Recluse Got Its Bite: Evolutionary Dynamics of Venom Toxins Across a Novel Toxin Recruitment"
|
10:15 am - 10:25 am |
Discussion
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10:25 am - 10:55 am |
Coffee Break
|
10:55 am - 11:25 am |
Ashlee Rowe (The University of Oklahoma, USA)
"Coevolution Between Bark Scorpion Neurotoxins and Voltage-Gated Sodium Ion Channels"
|
11:25 am - 11:35 am |
Discussion
|
11:35 am - 11:50 am |
Gregor Anderluh (National Institute of Chemistry, Slovenia)
"Molecular Evolution of Actinoporin-Like Proteins"
|
11:50 am - 11:55 am |
Discussion
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11:55 am - 12:10 pm |
Stephen Mackessy (University of Northern Colorado, USA)
"Taxon-Specific Toxins in Colubrid Snake Venoms: New Toxins with a Familiar Motif"
|
12:10 pm - 12:15 pm |
Discussion
|
12:15 pm - 12:30 pm |
Poster Previews
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 9:30 pm |
Next Generation Methods for Investigating Venom Components
Discussion Leader: Juan Calvete (Instituto de Biomedicina de Valencia, CSIC, Spain)
|
7:30 pm - 7:35 pm |
Introduction by Discussion Leader
|
7:35 pm - 8:05 pm |
Adam Claridge-Chang (Duke-NUS Medical School, Singapore)
"Genetically Encoded Compounds in a Genetic Model Animal: Towards Peptogenetics"
|
8:05 pm - 8:15 pm |
Discussion
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8:15 pm - 8:45 pm |
Beatrix Ueberheide (New York University, USA)
"NextGen Top-Down Proteomics of Crude Venom Mixtures"
|
8:45 pm - 8:55 pm |
Discussion
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8:55 pm - 9:05 pm |
Joachim Surm (Queensland University of Technology, Australia)
"Convergent Amplification and Functional Specialisation of Toxin and Toxin-Like Genes in Cnidarians"
|
9:05 pm - 9:10 pm |
Discussion
|
9:10 pm - 9:25 pm |
Somasekar Seshagiri (Genentech Inc, USA)
"The Genome and Transcriptome of the Indian Cobra"
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9:25 pm - 9:30 pm |
Discussion
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Tuesday
|
7:30 am - 8:30 am |
Breakfast
|
8:30 am - 9:00 am |
Group Photo
|
9:00 am - 12:30 pm |
Venom and Channels
Discussion Leader: Mandë Holford (Hunter College, City University of New York / American Museum of Natural History, USA)
|
9:00 am - 9:05 am |
Introduction by Discussion Leader
|
9:05 am - 9:35 am |
David Julius (University of California, San Francisco, USA)
"TRP Channel Structure and Function"
|
9:35 am - 9:45 am |
Discussion
|
9:45 am - 10:15 am |
Jan Tytgat (KU Leuven, Belgium)
"Venom Components with Insecticidal Activity in Major Animal Phyla"
|
10:15 am - 10:25 am |
Discussion
|
10:25 am - 10:55 am |
Coffee Break
|
10:55 am - 11:15 am |
Alexander Vassilevski (Institute of Bioorganic Chemistry, Russian Academy of Sciences, Russia)
"Gating Modifier Toxins Target Mutant Ion Channels Characteristic of Channelopathies"
|
11:15 am - 11:20 am |
Discussion
|
11:20 am - 11:40 am |
Yvonne Angell (ChemPartner, USA)
"Peptides 2020: A Clear Therapeutic Vision"
|
11:40 am - 11:45 am |
Discussion
|
11:45 am - 11:55 am |
Daniela Rojas (University of Costa Rica, Costa Rica)
"Biochemical Characterization of the Red Venom of the Neotropical Scorpion Didymocentrus krausi"
|
11:55 am - 12:00 pm |
Discussion
|
12:00 pm - 12:10 pm |
Kim Kirchhoff (Fraunhofer Institute for Molecular Biology and Applied Ecology, Germany)
"Harm and Heal? Pharmacological Potential of Stingray Venom"
|
12:10 pm - 12:15 pm |
Discussion
|
12:15 pm - 12:30 pm |
Poster Previews
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 9:30 pm |
Late-Breaking Topics
Discussion Leader: Lauren Esposito (California Academy of Sciences, USA)
|
7:30 pm - 7:35 pm |
Introduction by Discussion Leader
|
7:35 pm - 7:50 pm |
Cassandra Modahl (National University of Singapore, Singapore)
"Advantages of Venom Gland Transcriptomes for Venom Characterization"
|
7:50 pm - 7:55 pm |
Discussion
|
7:55 pm - 8:10 pm |
Lars Ellgaard (University of Copenhagen, Denmark)
"The First 3D Structure of an H-Superfamily Conotoxin: An Unexpected Fold from a Common Cysteine Framework"
|
8:10 pm - 8:15 pm |
Discussion
|
8:15 pm - 8:30 pm |
Angel Yanagihara (University of Hawaii, USA)
"Dendritic Cell Maturation Factor from Alatina alata Venom"
|
8:30 pm - 8:35 pm |
Discussion
|
8:35 pm - 8:50 pm |
Francis Markland (Keck School of Medicine, University of Southern California, USA)
"Preclinical Delivery Modalities for a Recombinant Disintegrin in Treating Different Types of Cancer"
|
8:50 pm - 8:55 pm |
Discussion
|
8:55 pm - 9:05 pm |
Micaiah Ward (Florida State University, USA)
"Experimental Evolution of Resistance: A New Paradigm for Venom Target Identification"
|
9:05 pm - 9:10 pm |
Discussion
|
9:10 pm - 9:25 pm |
Christina Schroeder (Institute for Molecular Bioscience, University of Queensland, Australia)
"The Use of Peptide-Membrane Interactions in the Design of Selective and Potent Sodium Channel Inhibitors"
|
9:25 pm - 9:30 pm |
Discussion
|
Wednesday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am - 12:30 pm |
Characterizing Venom Compounds
Discussion Leader: Ray Norton (Monash University, Australia)
|
9:00 am - 9:05 am |
Introduction by Discussion Leader
|
9:05 am - 9:35 am |
Irina Vetter (University of Queensland, Australia)
"Investigating Pain Pathways Using Venom Peptides"
|
9:35 am - 9:45 am |
Discussion
|
9:45 am - 10:15 am |
Yehu Moran (Alexander Silberman Institute of Life Sciences, Hebrew University of Jerusalem, Israel)
"Applying CRISPR to Modulate Venom Function"
|
10:15 am - 10:25 am |
Discussion
|
10:25 am - 10:55 am |
Coffee Break
|
10:55 am - 11:15 am |
Andrew Walker (The University of Queensland, Australia)
"Exploring the Diversity of Insect Venom Systems"
|
11:15 am - 11:20 am |
Discussion
|
11:20 am - 11:40 am |
Nicolas Gilles (CEA, France)
"Animal Toxins and GPCRs, a Promising Combination for Science and Medicine"
|
11:40 am - 11:45 am |
Discussion
|
11:45 am - 11:55 am |
Maria Sachkova (The Hebrew University of Jerusalem, Israel)
"The First Evidence for a Neuropeptide Recruited as a Neurotoxin"
|
11:55 am - 12:00 pm |
Discussion
|
12:00 pm - 12:10 pm |
Samantha Nixon (Institute for Molecular Bioscience, The University of Queensland / CSIRO Agriculture and Food, Australia)
"Arthropod Venoms for Next-Generation Antiparasitic Drug Discovery"
|
12:10 pm - 12:15 pm |
Discussion
|
12:15 pm - 12:30 pm |
Poster Previews
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:00 pm - 7:30 pm |
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
|
7:30 pm - 9:30 pm |
Molecular Basis for Venom Peptide Action
Discussion Leader: Denise Tambourgi (Instituto Butantan, Brazil)
|
7:30 pm - 7:35 pm |
Introduction by Discussion Leader
|
7:35 pm - 8:05 pm |
Gaurav Bhardwaj (University of Washington, USA)
"Accurate Computational Design of Hyperstable Constrained Peptides"
|
8:05 pm - 8:15 pm |
Discussion
|
8:15 pm - 8:25 pm |
Joseph Romano (Columbia University, USA)
"Engineering Innovative Informatics Solutions to Support Venom-Based Drug Discovery"
|
8:25 pm - 8:30 pm |
Discussion
|
8:30 pm - 9:00 pm |
Changlin Tian (University of Science and Technology of China, China)
"A Rugged Route from Venom Toxin to Peptide Drugs: Chemical Synthesis and Modification Leading to High Specificity and Potency"
|
9:00 pm - 9:10 pm |
Discussion
|
9:10 pm - 9:25 pm |
Abba Leffler (Schrödinger, USA)
"Is It Possible to Accurately Dock Toxin Peptides to Ion Channel Homology Models? Development, Testing and Experimental Validation of Toxdock"
|
9:25 pm - 9:30 pm |
Discussion
|
Thursday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am - 12:30 pm |
Venom and Toxin Diversity
Discussion Leader: Maria Vittoria Modica (Stazione Zoologica Anton Dohrn, Italy)
|
9:00 am - 9:05 am |
Introduction by Discussion Leader
|
9:05 am - 9:35 am |
Ricardo Rodriguez de la Vega (Université Paris-Sud, CNRS, France)
"Parallel Innovations Underlie Venom Evolution"
|
9:35 am - 9:45 am |
Discussion
|
9:45 am - 10:15 am |
Adam Reitzel (University of North Carolina at Charlotte, USA)
"Ecological Influences on Venom Expression in an Estuarine Cnidarian"
|
10:15 am - 10:25 am |
Discussion
|
10:25 am - 10:55 am |
Coffee Break
|
10:55 am - 11:05 am |
Michela Mitchell (Monash Institute of Pharmaceutical Sciences, Monash University, Australia)
"Endemic Australian Sea Anemone Venom: Evolution and Biology"
|
11:05 am - 11:10 am |
Discussion
|
11:10 am - 11:25 am |
Todd Castoe (University of Texas at Arlington, USA)
"Genome-Scale Perspectives on the Mechanisms Regulating Snake Venom Gene Specificity"
|
11:25 am - 11:30 am |
Discussion
|
11:30 am - 11:45 am |
Gisela Concepcion (The Marine Science Institute, Philippines)
"Turripeptides from Turrid Snails: Extending the Search for Neuroactive Peptide Drug Candidates to an Untapped Megadiverse Group of Conoideans"
|
11:45 am - 11:50 am |
Discussion
|
11:50 am - 12:05 pm |
Christian Gruber (Medical University of Vienna, Austria)
"Discovery, Biodiversity and Pharmacology of Circular Plant Peptide Toxins"
|
12:05 pm - 12:10 pm |
Discussion
|
12:10 pm - 12:25 pm |
Aida Verdes (Universidad Autónoma de Madrid, Spain)
"A Transcriptomic Approach to Explore the Diversity and Evolution of Annelid Venom Systems"
|
12:25 pm - 12:30 pm |
Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 9:30 pm |
Keynote Session: New Ground in Venom Research
Discussion Leader: R. Manjunatha Kini (National University of Singapore, Singapore)
|
7:30 pm - 7:35 pm |
Introduction by Discussion Leader
|
7:35 pm - 8:05 pm |
Denise Tambourgi (Instituto Butantan, Brazil)
"Venom Toxins, Cell Signaling and Immune Response"
|
8:05 pm - 8:15 pm |
Discussion
|
8:15 pm - 8:30 pm |
Fernanda Cardoso (The University of Queensland, Australia)
"Counter Screen of Spider Venoms Reveals Novel Sodium and Calcium Channel Inhibitors of Chronic Pain Targets"
|
8:30 pm - 8:35 pm |
Discussion
|
8:35 pm - 9:05 pm |
Glenn King (University of Queensland, Australia)
"The Future of Venom-Derived Drugs: Fake News Versus Real-World Solutions"
|
9:05 pm - 9:15 pm |
Discussion
|
9:15 pm - 9:30 pm |
Closing Remarks
|
Friday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am |
Departure
|