Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Establishing Vascular Heterogenity
Discussion Leader: Ralf Adams (Max Planck Institute for Molecular Biomedicine, Germany)
7:40 pm - 7:45 pm
General Discussion
7:45 pm - 8:00 pm
Introduction by Discussion Leader
8:00 pm - 8:20 pm
Kristy Red-Horse (HHMI/Stanford University, United States)
"Establishing Endothelial Arterial-Venous Identity"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Brant Weinstein (National Institute of Child Health and Human Development, United States)
"Vascular Diversity in the Brain"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Lisandra Vila Ellis (Northwestern University, United States)
"Vascular Cells in the Lung"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Maintaining Vascular Heterogeneity: Resilience
Discussion Leader: Luisa Iruela-Arispe (Northwestern University, United States)
9:00 am - 9:15 am
General Discussion
9:15 am - 9:35 am
Zorina Galis (National Institutes of Health, United States)
"Importance of Vascular Resilience in Disease Prevention"
9:35 am - 9:45 am
Discussion
9:45 am - 10:05 am
Stefanie Dimmeler (Goethe-University Frankfurt, Germany)
"Regulation of Cardiovascular Resilience"
10:05 am - 10:15 am
Discussion
10:15 am - 10:25 am
Short Talk Selected from Poster Abstracts
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Joshua Scallan (University of South Florida, United States)
"Maintenance of Lymphatic Vascular"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
Joseph Miano (Augusta University, United States)
"Emerging VSMC Phenotypes from a More Restrictive Cre Driver"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Victoria Bautch (University of North Carolina at Chapel Hill, United States) and Mara Pitulescu (Max Planck Institute for Molecular Biomedicine Münster, Germany)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Regulation by Mechanical Forces
Discussion Leader: Ellie Tzima (University of Oxford, United Kingdom)
7:30 pm - 7:50 pm
Michel Bagnat (Duke University, United States)
"Mechanical Inputs Patterning the Vertebrate AP Axis"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Martin Schwartz (Yale School of Medicine, United States)
"How Fluid Shear Stress Determines Endothelial Cell Phenotype"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Short Talk Selected from Poster Abstracts
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Short Talk Selected from Poster Abstracts
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Rashmi Priya (The Francis Crick Institute, London, United Kingdom)
"Living Machines: How to Build a Functional Heart"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Metabolic Regulation
Discussion Leader: Michael Potente (Berlin Institute of Health at Charité & Max Delbrück Center for Molecular Medicine, Germany)
9:00 am - 9:20 am
Olivier Pourquie (Harvard Medical School / Brigham and Women's Hospital, United States)
"Reconstructing the Human Musculo-Skeletal System in vitro"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Zoltan Arany (University of Pennsylvania, United States)
"NAD in the Endothelium"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
Short Talk Selected from Poster Abstracts
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Short Talk Selected from Poster Abstracts
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Mariona Graupera (Josep Carreras Leukaemia Research Institute, Spain)
"Understanding Endothelial Cell Behaviors in Adipose Tissue"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
Timothy Hla (Boston Children's Hospital and Harvard Medical School, United States)
"Sphingolipid Metabolism and Signaling in the Vascular System"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Sex-Related Differences in Vascular Biology
Discussion Leader: Mark Kahn (University of Pennsylvania, United States)
7:30 pm - 7:50 pm
Nina Stachenfeld (John B. Pierce Lab/Yale School of Medicine, United States)
"Reproductive Hormone Effects on Endothelial Function in Humans"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Mete Civelek (University of Virginia, United States)
"Systems Genetics of Sex Differences in Vascular Cell Gene Regulation"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Short Talk Selected from Poster Abstracts
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Short Talk Selected from Poster Abstracts
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Hester Den Ruijter (UMC Utrecht, The Netherlands)
"Sex Differences in Atherosclerosis"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Imaging and Genomic Approaches
Discussion Leader: Rui Benedito (Centro Nacional de Investigaciones Cardiovasculares (CNIC), Spain)
9:00 am - 9:20 am
Mary Dickinson (Baylor College of Medicine, United States)
"Establishing and Maintaining Research Infrastructure"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Joshua Wythe (University of Virginia School of Medicine, United States)
"Whole Animal 3D Vascular Imaging"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
Short Talk Selected from Poster Abstracts
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Short Talk Selected from Poster Abstracts
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Mauro Siragusa (Institute for Vascular Signalling, Goethe University Frankfurt, Germany, Germany)
"Identification and Function of Endothelial Cell Microproteins: Challenges and Opportunities"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
Joanna Kalucka (Aarhus University, Denmark)
"Defining the Vascular Niche of Human Adipose Tissue Across Metabolic Conditions"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Cellular Damage, Repair and Regeneration
Discussion Leader: Christiana Ruhrberg (University College London, United Kingdom)
7:30 pm - 7:50 pm
Maria Barna (Stanford University, United States)
"Regulation of Regeneration in Amphibians"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Mark Majesky (Seattle Children's Research Institute, University of Washington, United States)
"Mammalian Organ Regeneration in Spiny Mice"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Short Talk Selected from Poster Abstracts
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Short Talk Selected from Poster Abstracts
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Sharon Gerecht (Duke University, United States)
"Vascular Differentiation and Morphogenesis"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Epigenetic Regulation and Epitranscriptomics
Discussion Leader: Anna Randi (Imperial College London, United Kingdom)
9:00 am - 9:20 am
Siyuan Wang (Yale University, United States)
"Image-Based 3D Genomics and Epigenomics"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Courtney Griffin (Oklahoma Medical Research Foundation, United States)
"Leveraging Chromatin-Remodeling Enzymes To Study Vascular Development and Maintenance"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
Short Talk Selected from Poster Abstracts
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Short Talk Selected from Poster Abstracts
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Delphine Gomez (University of Pittsburgh, United States)
"Epigenetic Control of SMC Contractility and Adaptive Remodeling"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
Kaska Koltowska (Uppsala University, Sweden)
"Mapping Chromatin Landscape and Regulatory Logic behind Lymphatic Endothelial Cell Differentiation"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Congenital Vascular Disorders and Therapy
Discussion Leader: Joyce Bischoff (Boston Children's Hospital and Harvard Medical School, United States)
7:30 pm - 7:50 pm
Miikka Vikkula (Institute de Duve / UCLouvain, Belgium)
"Vascular Malformations: Genetic Causes, Preclinical Models and Clinical Trials."
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Taija Makinen (University of Helsinki, Wihuri Research Institute / Uppsala University, Finland)
"Pathogenic Mechanisms of PIK3CA-Driven Vascular Malformations"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Short Talk Selected from Poster Abstracts
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Short Talk Selected from Poster Abstracts
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
S. Paul Oh (Barrow Neurological Institute, United States)
"Unraveling Mechanisms and Therapeutic Targets for HHT through Endothelial Cells Derived from Mutant iPSCs"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure