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Angiogenesis and Microcirculation

Gordon Research Conference

August 17 - 22, 1997
Chair Harold F. Dvorak
Vice Chair Patricia A. D'Amore
Salve Regina University
100 Ochre Point Avenue
Newport, RI, United States
 Venue and Travel Information

Conference Program

Sunday PM

Vascular Development

Chair: Werner Risau
  • Peter Carmeliet - "Analysis of PIGF and VEGF Mutant Mice"
  • Kari Alitalo - "A Family of VEGF's and Receptors Involved in Angiogenesis and Lymphangiogenesis"
  • George Yancopoulos - "The Angiopoietin Family"

Monday AM

Matrix and Angiogenesis

Chair: Helene Sage
  • Roberto Nicosia - "Endothelial-Stromal Cell Interactions in Angiogenesis"
  • Donald R. Senger - "Regulation of VPF/VEGF Directed Angiogenesis by Extracellular Matrix"
  • Michael Pepper - "Context and Balance: Paradigms which Reveal Complexity in the Regulation of Angiogenesis"
  • David Cheresh - "Integrins, Proteases and Angiogenesis: Therapeutic Implications"
  • Marsha Moses - "The Regulation of Neurovascularization by Matrix Metalloproteinases and their Inhibitors"

Monday PM

Pathways of Microvascular Permeability

Chair: Harold F. Dvorak
  • Charles Michel - "How Does Microvascular Permeability Increase?"
  • Donald McDonald - "Endothelial Permeability and Angiogenesis in Chronic Inflammation"
  • Ann Dvorak - "Vesico-Vacuolar Organelles"

Tuesday AM

Growth Factor Regulation

Chair: Noel Bouck
  • Robert Kerbel - "Oncogenes and Proto-Oncogenes as Inducers of Tumor Angiogenesis: Biological and Therapeutic Implications"
  • Sabine Werner - "Regulation and Function of Growth Factors in Inflammation and Repair"
  • Rakesh Jain - "Role of VEGF in Vascular Permeability and Adhesion"
  • Werner Risau - "Initiation and Maintenance of Endothelial Phenotypes"

Tuesday PM

Endothelial Cell Signalling

Chair: Dieter Marme
  • Carl-Henrik Heldin - "Signaling through PDGF Receptors"
  • Martin Schwartz - "Signal Transduction by Integrins"
  • Jan Schnitzer - "Caveolae-Mediated Cell Surface Signaling and Transport: New Targets for Drug and Gene Therapy In Vivo"
  • Martyn Gabbinck (10 min) - "The Role of Receptor Tyrosine Phosphatase RPTP in Endothelial Cells"

Wednesday AM

Endothelial Cell Regulation

Chair: Jack Lawler
  • Luisa Iruela-Arispe - "Regulation of Endothelial Cell Function by Thrombospondin-1 and by Two Novel Members of the Thrombospondin Super-Family of Proteins"
  • Bjorn Olsen - "Endothelial Cell Signaling in Vasculogenesis"
  • Michael Gimbrone - "Vascular Endothelium, Biomechanical Forces and Gene Regulation"
  • Jeffrey Isner - "Therapeutic Angiogenic: Cytokine Enhancement and Stem Cell Grafts"
  • Joseph Madri - "ECM/Integrin Mediated Modulation of PECAM-1 Tyrosine Phosphorylation: Implications for Endothelial Migration and Vasculogenesis"

Wednesday PM

Endothelial Cell Interactions with Other Cells I

Chair: Patricia D'Amore
  • Patricia D'Amore - "Cell-cell Interactions in Vascular Development and Differentiation"
  • Monika Schmelz - "Complexus Adhaerentes, a Special Type of Adhering Junctions in Lymphatic Endothelial Cells"
  • David Paul - "Communication in the Cardiovascular System"

Thursday AM

Endothelial Cell Interactions with Other Cells II

Chair: Ramzi Cotran
  • Denisa Wagner - "Leucocyte Adhesion Receptors in Atherosclerosis and Obesity"
  • Gerd Schmid-Schoenbein - "The Response of Leucocytes to Shear Stress"
  • David Milstone - "Vascular Endothelial Differentiation and Functional Maturation during Normal Ontogeny and in Differentiated Emryonic Stem Cells"
  • Elisabetta Dejana - "Molecular Organization of Endothelial Cell to Cell Junctions and Leucocyte Transmigration"

Thursday PM

Angiogenesis Inhibition

Chair: Judah Folkman
  • Napoleane Ferrara - "Regulation of Angiogenesis by VEGF"
  • Kenneth Thomas - "Therapeutic Control of Angiogenesis"
  • Judah Folkman - "Anti-angiogenic Therapy"

Contributors

We are grateful for financial support from the following:

Biochem-Pharma
Hybridon, Inc.
Abbot Labs
BASF Bioresearch Corp.
Biogen
Bristol-Meyers Squibb
Entremed, Inc.
Merck Darmstadt
Merck & Company
Proctor & Gamble
Scios, Inc.
Searle
Smith Kline Beacham

Conference Links

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